These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

1455 related items for PubMed ID: 34505574

  • 1. End-of-life targeted degradation of DAF-2 insulin/IGF-1 receptor promotes longevity free from growth-related pathologies.
    Venz R, Pekec T, Katic I, Ciosk R, Ewald CY.
    Elife; 2021 Sep 10; 10():. PubMed ID: 34505574
    [Abstract] [Full Text] [Related]

  • 2. Untangling Longevity, Dauer, and Healthspan in Caenorhabditis elegans Insulin/IGF-1-Signalling.
    Ewald CY, Castillo-Quan JI, Blackwell TK.
    Gerontology; 2018 Sep 10; 64(1):96-104. PubMed ID: 28934747
    [Abstract] [Full Text] [Related]

  • 3. Mutation of daf-2 extends lifespan via tissue-specific effectors that suppress distinct life-limiting pathologies.
    Zhao Y, Zhang B, Marcu I, Athar F, Wang H, Galimov ER, Chapman H, Gems D.
    Aging Cell; 2021 Mar 10; 20(3):e13324. PubMed ID: 33609424
    [Abstract] [Full Text] [Related]

  • 4. DAF-2/insulin IGF-1 receptor regulates motility during aging by integrating opposite signaling from muscle and neuronal tissues.
    Roy C, Molin L, Alcolei A, Solyga M, Bonneau B, Vachon C, Bessereau JL, Solari F.
    Aging Cell; 2022 Aug 10; 21(8):e13660. PubMed ID: 35808897
    [Abstract] [Full Text] [Related]

  • 5. A PTEN variant uncouples longevity from impaired fitness in Caenorhabditis elegans with reduced insulin/IGF-1 signaling.
    Park HH, Hwang W, Ham S, Kim E, Altintas O, Park S, Son HG, Lee Y, Lee D, Heo WD, Lee SV.
    Nat Commun; 2021 Sep 24; 12(1):5631. PubMed ID: 34561453
    [Abstract] [Full Text] [Related]

  • 6. Intestine-specific removal of DAF-2 nearly doubles lifespan in Caenorhabditis elegans with little fitness cost.
    Zhang YP, Zhang WH, Zhang P, Li Q, Sun Y, Wang JW, Zhang SO, Cai T, Zhan C, Dong MQ.
    Nat Commun; 2022 Oct 25; 13(1):6339. PubMed ID: 36284093
    [Abstract] [Full Text] [Related]

  • 7. Insulin/IGF-1-mediated longevity is marked by reduced protein metabolism.
    Stout GJ, Stigter EC, Essers PB, Mulder KW, Kolkman A, Snijders DS, van den Broek NJ, Betist MC, Korswagen HC, Macinnes AW, Brenkman AB.
    Mol Syst Biol; 2013 Jul 02; 9():679. PubMed ID: 23820781
    [Abstract] [Full Text] [Related]

  • 8. The protein kinase MBK-1 contributes to lifespan extension in daf-2 mutant and germline-deficient Caenorhabditis elegans.
    Mack HID, Zhang P, Fonslow BR, Yates JR.
    Aging (Albany NY); 2017 May 25; 9(5):1414-1432. PubMed ID: 28562327
    [Abstract] [Full Text] [Related]

  • 9. PDP-1 links the TGF-β and IIS pathways to regulate longevity, development, and metabolism.
    Narasimhan SD, Yen K, Bansal A, Kwon ES, Padmanabhan S, Tissenbaum HA.
    PLoS Genet; 2011 Apr 25; 7(4):e1001377. PubMed ID: 21533078
    [Abstract] [Full Text] [Related]

  • 10. Insulin and IGF-1 extend the lifespan of Caenorhabditis elegans by inhibiting insulin/insulin-like signaling and mTOR signaling pathways: C. elegans - Focused cancer research.
    Berk Ş.
    Biochem Biophys Res Commun; 2024 Oct 15; 729():150347. PubMed ID: 38976945
    [Abstract] [Full Text] [Related]

  • 11. Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C. elegans.
    Sun Y, Li M, Zhao D, Li X, Yang C, Wang X.
    Elife; 2020 Jun 02; 9():. PubMed ID: 32482227
    [Abstract] [Full Text] [Related]

  • 12. Activated AKT/PKB signaling in C. elegans uncouples temporally distinct outputs of DAF-2/insulin-like signaling.
    Gami MS, Iser WB, Hanselman KB, Wolkow CA.
    BMC Dev Biol; 2006 Oct 04; 6():45. PubMed ID: 17020605
    [Abstract] [Full Text] [Related]

  • 13. pkc-1 regulates daf-2 insulin/IGF signalling-dependent control of dauer formation in Caenorhabditis elegans.
    Monje JM, Brokate-Llanos AM, Pérez-Jiménez MM, Fidalgo MA, Muñoz MJ.
    Aging Cell; 2011 Dec 04; 10(6):1021-31. PubMed ID: 21933341
    [Abstract] [Full Text] [Related]

  • 14. Germline signaling mediates the synergistically prolonged longevity produced by double mutations in daf-2 and rsks-1 in C. elegans.
    Chen D, Li PW, Goldstein BA, Cai W, Thomas EL, Chen F, Hubbard AE, Melov S, Kapahi P.
    Cell Rep; 2013 Dec 26; 5(6):1600-10. PubMed ID: 24332851
    [Abstract] [Full Text] [Related]

  • 15. RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling in Caenorhabditis elegans.
    Seo M, Seo K, Hwang W, Koo HJ, Hahm JH, Yang JS, Han SK, Hwang D, Kim S, Jang SK, Lee Y, Nam HG, Lee SJ.
    Proc Natl Acad Sci U S A; 2015 Aug 04; 112(31):E4246-55. PubMed ID: 26195740
    [Abstract] [Full Text] [Related]

  • 16. Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling.
    Lin K, Hsin H, Libina N, Kenyon C.
    Nat Genet; 2001 Jun 04; 28(2):139-45. PubMed ID: 11381260
    [Abstract] [Full Text] [Related]

  • 17. Cholesterol regulates DAF-16 nuclear localization and fasting-induced longevity in C. elegans.
    Ihara A, Uno M, Miyatake K, Honjoh S, Nishida E.
    Exp Gerontol; 2017 Jan 04; 87(Pt A):40-47. PubMed ID: 27989925
    [Abstract] [Full Text] [Related]

  • 18. TATN-1 mutations reveal a novel role for tyrosine as a metabolic signal that influences developmental decisions and longevity in Caenorhabditis elegans.
    Ferguson AA, Roy S, Kormanik KN, Kim Y, Dumas KJ, Ritov VB, Matern D, Hu PJ, Fisher AL.
    PLoS Genet; 2013 Jan 04; 9(12):e1004020. PubMed ID: 24385923
    [Abstract] [Full Text] [Related]

  • 19. C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation.
    Hahm JH, Kim S, DiLoreto R, Shi C, Lee SJ, Murphy CT, Nam HG.
    Nat Commun; 2015 Nov 20; 6():8919. PubMed ID: 26586186
    [Abstract] [Full Text] [Related]

  • 20. RNA helicase SACY-1 is required for longevity caused by various genetic perturbations in Caenorhabditis elegans.
    Seo M, Park S, Nam HG, Lee SJ.
    Cell Cycle; 2016 Jul 17; 15(14):1821-9. PubMed ID: 27153157
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 73.