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Journal Abstract Search

116 related items for PubMed ID: 34542380

  • 1. Molecular modeling and dynamics studies of the synthetic small molecule agonists with GPR17 and P2Y1 receptor.
    Murugesan A, Nguyen P, Ramesh T, Yli-Harja O, Kandhavelu M, Saravanan KM.
    J Biomol Struct Dyn; 2022; 40(23):12908-12916. PubMed ID: 34542380
    [Abstract] [Full Text] [Related]

  • 2. Identification of novel GPR17-agonists by structural bioinformatics and signaling activation.
    Saravanan KM, Palanivel S, Yli-Harja O, Kandhavelu M.
    Int J Biol Macromol; 2018 Jan; 106():901-907. PubMed ID: 28827203
    [Abstract] [Full Text] [Related]

  • 3. Structural analysis of human G-protein-coupled receptor 17 ligand binding sites.
    Konda Mani S, Thiyagarajan R, Yli-Harja O, Kandhavelu M, Murugesan A.
    J Cell Biochem; 2023 Apr; 124(4):533-544. PubMed ID: 36791278
    [Abstract] [Full Text] [Related]

  • 4. Agonist-induced desensitization/resensitization of human G protein-coupled receptor 17: a functional cross-talk between purinergic and cysteinyl-leukotriene ligands.
    Daniele S, Trincavelli ML, Gabelloni P, Lecca D, Rosa P, Abbracchio MP, Martini C.
    J Pharmacol Exp Ther; 2011 Aug; 338(2):559-67. PubMed ID: 21531793
    [Abstract] [Full Text] [Related]

  • 5. GPR17: molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors.
    Parravicini C, Ranghino G, Abbracchio MP, Fantucci P.
    BMC Bioinformatics; 2008 Jun 04; 9():263. PubMed ID: 18533035
    [Abstract] [Full Text] [Related]

  • 6. The Orphan Receptor GPR17 Is Unresponsive to Uracil Nucleotides and Cysteinyl Leukotrienes.
    Simon K, Merten N, Schröder R, Hennen S, Preis P, Schmitt NK, Peters L, Schrage R, Vermeiren C, Gillard M, Mohr K, Gomeza J, Kostenis E.
    Mol Pharmacol; 2017 May 04; 91(5):518-532. PubMed ID: 28254957
    [Abstract] [Full Text] [Related]

  • 7. The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor.
    Ciana P, Fumagalli M, Trincavelli ML, Verderio C, Rosa P, Lecca D, Ferrario S, Parravicini C, Capra V, Gelosa P, Guerrini U, Belcredito S, Cimino M, Sironi L, Tremoli E, Rovati GE, Martini C, Abbracchio MP.
    EMBO J; 2006 Oct 04; 25(19):4615-27. PubMed ID: 16990797
    [Abstract] [Full Text] [Related]

  • 8. Is GPR17 a P2Y/leukotriene receptor? examination of uracil nucleotides, nucleotide sugars, and cysteinyl leukotrienes as agonists of GPR17.
    Qi AD, Harden TK, Nicholas RA.
    J Pharmacol Exp Ther; 2013 Oct 04; 347(1):38-46. PubMed ID: 23908386
    [Abstract] [Full Text] [Related]

  • 9. Distinct expression and ligand-binding profiles of two constitutively active GPR17 splice variants.
    Benned-Jensen T, Rosenkilde MM.
    Br J Pharmacol; 2010 Mar 04; 159(5):1092-105. PubMed ID: 20148890
    [Abstract] [Full Text] [Related]

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  • 11. Transcriptomic analysis of glioblastoma multiforme providing new insights into GPR17 signaling communication.
    Mutharasu G, Murugesan A, Konda Mani S, Yli-Harja O, Kandhavelu M.
    J Biomol Struct Dyn; 2022 Apr 04; 40(6):2586-2599. PubMed ID: 33140689
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  • 14. A promiscuous recognition mechanism between GPR17 and SDF-1: Molecular insights.
    Parravicini C, Daniele S, Palazzolo L, Trincavelli ML, Martini C, Zaratin P, Primi R, Coppolino G, Gianazza E, Abbracchio MP, Eberini I.
    Cell Signal; 2016 Jun 04; 28(6):631-42. PubMed ID: 26971834
    [Abstract] [Full Text] [Related]

  • 15. In silico identification of new ligands for GPR17: a promising therapeutic target for neurodegenerative diseases.
    Eberini I, Daniele S, Parravicini C, Sensi C, Trincavelli ML, Martini C, Abbracchio MP.
    J Comput Aided Mol Des; 2011 Aug 04; 25(8):743-52. PubMed ID: 21744154
    [Abstract] [Full Text] [Related]

  • 16. Frontal affinity chromatography-mass spectrometry useful for characterization of new ligands for GPR17 receptor.
    Calleri E, Ceruti S, Cristalli G, Martini C, Temporini C, Parravicini C, Volpini R, Daniele S, Caccialanza G, Lecca D, Lambertucci C, Trincavelli ML, Marucci G, Wainer IW, Ranghino G, Fantucci P, Abbracchio MP, Massolini G.
    J Med Chem; 2010 May 13; 53(9):3489-501. PubMed ID: 20394377
    [Abstract] [Full Text] [Related]

  • 17. Enigmatic GPCR finds a stimulating drug.
    Harden TK.
    Sci Signal; 2013 Oct 22; 6(298):pe34. PubMed ID: 24150253
    [Abstract] [Full Text] [Related]

  • 18. The Orphan G Protein-coupled Receptor GPR17 Negatively Regulates Oligodendrocyte Differentiation via Gαi/o and Its Downstream Effector Molecules.
    Simon K, Hennen S, Merten N, Blättermann S, Gillard M, Kostenis E, Gomeza J.
    J Biol Chem; 2016 Jan 08; 291(2):705-18. PubMed ID: 26620557
    [Abstract] [Full Text] [Related]

  • 19. Expression of dual nucleotides/cysteinyl-leukotrienes receptor GPR17 in early trafficking of cardiac stromal cells after myocardial infarction.
    Cosentino S, Castiglioni L, Colazzo F, Nobili E, Tremoli E, Rosa P, Abbracchio MP, Sironi L, Pesce M.
    J Cell Mol Med; 2014 Sep 08; 18(9):1785-96. PubMed ID: 24909956
    [Abstract] [Full Text] [Related]

  • 20. The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair.
    Lecca D, Trincavelli ML, Gelosa P, Sironi L, Ciana P, Fumagalli M, Villa G, Verderio C, Grumelli C, Guerrini U, Tremoli E, Rosa P, Cuboni S, Martini C, Buffo A, Cimino M, Abbracchio MP.
    PLoS One; 2008 Sep 08; 3(10):e3579. PubMed ID: 18974869
    [Abstract] [Full Text] [Related]

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