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123 related items for PubMed ID: 34624316

  • 1. Identification of Rac guanine nucleotide exchange factors promoting Lgl1 phosphorylation in glioblastoma.
    Lavictoire SJ, Jomaa D, Gont A, Jardine K, Cook DP, Lorimer IAJ.
    J Biol Chem; 2021 Nov; 297(5):101172. PubMed ID: 34624316
    [Abstract] [Full Text] [Related]

  • 2. PREX1 integrates G protein-coupled receptor and phosphoinositide 3-kinase signaling to promote glioblastoma invasion.
    Gont A, Daneshmand M, Woulfe J, Lavictoire SJ, Lorimer IA.
    Oncotarget; 2017 Jan 31; 8(5):8559-8573. PubMed ID: 28051998
    [Abstract] [Full Text] [Related]

  • 3. PREX1 Protein Function Is Negatively Regulated Downstream of Receptor Tyrosine Kinase Activation by p21-activated Kinases (PAKs).
    Barrows D, He JZ, Parsons R.
    J Biol Chem; 2016 Sep 16; 291(38):20042-54. PubMed ID: 27481946
    [Abstract] [Full Text] [Related]

  • 4. PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling.
    Liu HJ, Ooms LM, Srijakotre N, Man J, Vieusseux J, Waters JE, Feng Y, Bailey CG, Rasko JE, Price JT, Mitchell CA.
    J Biol Chem; 2016 Aug 12; 291(33):17258-70. PubMed ID: 27358402
    [Abstract] [Full Text] [Related]

  • 5. Regulation of breast cancer cell motility by T-cell lymphoma invasion and metastasis-inducing protein.
    Adams HC, Chen R, Liu Z, Whitehead IP.
    Breast Cancer Res; 2010 Aug 12; 12(5):R69. PubMed ID: 20819206
    [Abstract] [Full Text] [Related]

  • 6. Aberrant Rac pathway signalling in glioblastoma.
    Lorimer IA.
    Small GTPases; 2021 Mar 12; 12(2):81-95. PubMed ID: 31032735
    [Abstract] [Full Text] [Related]

  • 7. Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin.
    Buchsbaum RJ, Connolly BA, Feig LA.
    J Biol Chem; 2003 May 23; 278(21):18833-41. PubMed ID: 12531897
    [Abstract] [Full Text] [Related]

  • 8. Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1.
    Van Leeuwen FN, Olivo C, Grivell S, Giepmans BN, Collard JG, Moolenaar WH.
    J Biol Chem; 2003 Jan 03; 278(1):400-6. PubMed ID: 12393875
    [Abstract] [Full Text] [Related]

  • 9. Hepatocyte growth factor triggers distinct mechanisms of Asef and Tiam1 activation to induce endothelial barrier enhancement.
    Higginbotham K, Tian Y, Gawlak G, Moldobaeva N, Shah A, Birukova AA.
    Cell Signal; 2014 Nov 03; 26(11):2306-16. PubMed ID: 25101856
    [Abstract] [Full Text] [Related]

  • 10. The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.
    Malliri A, Rygiel TP, van der Kammen RA, Song JY, Engers R, Hurlstone AF, Clevers H, Collard JG.
    J Biol Chem; 2006 Jan 06; 281(1):543-8. PubMed ID: 16249175
    [Abstract] [Full Text] [Related]

  • 11. The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration.
    Saxena M, Dykes SS, Malyarchuk S, Wang AE, Cardelli JA, Pruitt K.
    Oncogene; 2015 Jan 08; 34(2):188-98. PubMed ID: 24362520
    [Abstract] [Full Text] [Related]

  • 12. Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation.
    Barrio-Real L, Benedetti LG, Engel N, Tu Y, Cho S, Sukumar S, Kazanietz MG.
    Breast Cancer Res; 2014 Sep 24; 16(5):441. PubMed ID: 25248717
    [Abstract] [Full Text] [Related]

  • 13. The Rac-GAP Bcr is a novel regulator of the Par complex that controls cell polarity.
    Narayanan AS, Reyes SB, Um K, McCarty JH, Tolias KF.
    Mol Biol Cell; 2013 Dec 24; 24(24):3857-68. PubMed ID: 24152735
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of glioblastoma malignancy by Lgl1.
    Gont A, Hanson JE, Lavictoire SJ, Daneshmand M, Nicholas G, Woulfe J, Kassam A, Da Silva VF, Lorimer IA.
    Oncotarget; 2014 Nov 30; 5(22):11541-51. PubMed ID: 25426552
    [Abstract] [Full Text] [Related]

  • 15. Translocation of the Rac1 guanine nucleotide exchange factor Tiam1 induced by platelet-derived growth factor and lysophosphatidic acid.
    Buchanan FG, Elliot CM, Gibbs M, Exton JH.
    J Biol Chem; 2000 Mar 31; 275(13):9742-8. PubMed ID: 10734127
    [Abstract] [Full Text] [Related]

  • 16. The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.
    Boissier P, Huynh-Do U.
    Cell Signal; 2014 Mar 31; 26(3):483-91. PubMed ID: 24308970
    [Abstract] [Full Text] [Related]

  • 17. Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration.
    Wang S, Watanabe T, Matsuzawa K, Katsumi A, Kakeno M, Matsui T, Ye F, Sato K, Murase K, Sugiyama I, Kimura K, Mizoguchi A, Ginsberg MH, Collard JG, Kaibuchi K.
    J Cell Biol; 2012 Oct 15; 199(2):331-45. PubMed ID: 23071154
    [Abstract] [Full Text] [Related]

  • 18. The role of the guanine nucleotide exchange factor Tiam1 in cellular migration, invasion, adhesion and tumor progression.
    Minard ME, Kim LS, Price JE, Gallick GE.
    Breast Cancer Res Treat; 2004 Mar 15; 84(1):21-32. PubMed ID: 14999151
    [Abstract] [Full Text] [Related]

  • 19. The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.
    Leeuwen FN, Kain HE, Kammen RA, Michiels F, Kranenburg OW, Collard JG.
    J Cell Biol; 1997 Nov 03; 139(3):797-807. PubMed ID: 9348295
    [Abstract] [Full Text] [Related]

  • 20. Rac-1 superactivation triggers insulin-independent glucose transporter 4 (GLUT4) translocation that bypasses signaling defects exerted by c-Jun N-terminal kinase (JNK)- and ceramide-induced insulin resistance.
    Chiu TT, Sun Y, Koshkina A, Klip A.
    J Biol Chem; 2013 Jun 14; 288(24):17520-31. PubMed ID: 23640896
    [Abstract] [Full Text] [Related]

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