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Journal Abstract Search

204 related items for PubMed ID: 34653770

  • 1. Design, synthesis, and mechanistic investigations of phenylalanine derivatives containing a benzothiazole moiety as HIV-1 capsid inhibitors with improved metabolic stability.
    Xu S, Sun L, Dick A, Zalloum WA, Huang T, Meuser ME, Zhang X, Tao Y, Cherukupalli S, Ding D, Ding X, Gao S, Jiang X, Kang D, De Clercq E, Pannecouque C, Cocklin S, Liu X, Zhan P.
    Eur J Med Chem; 2022 Jan 05; 227():113903. PubMed ID: 34653770
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  • 4. Design, Synthesis and Characterization of HIV-1 CA-Targeting Small Molecules: Conformational Restriction of PF74.
    Sahani RL, Diana-Rivero R, Vernekar SKV, Wang L, Du H, Zhang H, Castaner AE, Casey MC, Kirby KA, Tedbury PR, Xie J, Sarafianos SG, Wang Z.
    Viruses; 2021 Mar 15; 13(3):. PubMed ID: 33804121
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  • 5. Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities.
    Sun L, Dick A, Meuser ME, Huang T, Zalloum WA, Chen CH, Cherukupalli S, Xu S, Ding X, Gao P, Kang D, De Clercq E, Pannecouque C, Cocklin S, Lee KH, Liu X, Zhan P.
    J Med Chem; 2020 May 14; 63(9):4790-4810. PubMed ID: 32298111
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  • 6. Design, synthesis and structure-activity relationships of 4-phenyl-1H-1,2,3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral activities.
    Sun L, Huang T, Dick A, Meuser ME, Zalloum WA, Chen CH, Ding X, Gao P, Cocklin S, Lee KH, Zhan P, Liu X.
    Eur J Med Chem; 2020 Mar 15; 190():112085. PubMed ID: 32066010
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  • 7. Novel HIV-1 capsid-targeting small molecules of the PF74 binding site.
    Wang L, Casey MC, Vernekar SKV, Sahani RL, Kankanala J, Kirby KA, Du H, Hachiya A, Zhang H, Tedbury PR, Xie J, Sarafianos SG, Wang Z.
    Eur J Med Chem; 2020 Oct 15; 204():112626. PubMed ID: 32814250
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  • 8. Discovery and Mechanistic Investigation of Piperazinone Phenylalanine Derivatives with Terminal Indole or Benzene Ring as Novel HIV-1 Capsid Modulators.
    Xu S, Sun L, Zalloum WA, Huang T, Zhang X, Ding D, Shao X, Jiang X, Zhao F, Cocklin S, De Clercq E, Pannecouque C, Dick A, Liu X, Zhan P.
    Molecules; 2022 Dec 01; 27(23):. PubMed ID: 36500508
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  • 9. Design, synthesis, and antiviral activity of phenylalanine derivatives as HIV-1 capsid inhibitors.
    Li J, Jiang X, Dick A, Prakash Sharma P, Chen CH, Rathi B, Kang D, Wang Z, Ji X, Lee KH, Cocklin S, Liu X, Zhan P.
    Bioorg Med Chem; 2021 Oct 15; 48():116414. PubMed ID: 34562701
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  • 10. Toward Structurally Novel and Metabolically Stable HIV-1 Capsid-Targeting Small Molecules.
    Vernekar SKV, Sahani RL, Casey MC, Kankanala J, Wang L, Kirby KA, Du H, Zhang H, Tedbury PR, Xie J, Sarafianos SG, Wang Z.
    Viruses; 2020 Apr 16; 12(4):. PubMed ID: 32316297
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  • 11. Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74.
    Saito A, Ferhadian D, Sowd GA, Serrao E, Shi J, Halambage UD, Teng S, Soto J, Siddiqui MA, Engelman AN, Aiken C, Yamashita M.
    J Virol; 2016 Jun 15; 90(12):5808-5823. PubMed ID: 27076642
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  • 16. Synthesis, Enantiomeric Resolution and Biological Evaluation of HIV Capsid Inhibition Activity for Racemic, (S)- and (R)-PF74.
    Ruddell S, Sugrue E, Memarzadeh S, Hellam LM, Wilson SJ, France DJ.
    Molecules; 2021 Jun 26; 26(13):. PubMed ID: 34206893
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