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1495 related items for PubMed ID: 34655668

  • 1. A new discovery: Total Bupleurum saponin extracts can inhibit the proliferation and induce apoptosis of colon cancer cells by regulating the PI3K/Akt/mTOR pathway.
    Zhang X, Liu Z, Chen S, Li H, Dong L, Fu X.
    J Ethnopharmacol; 2022 Jan 30; 283():114742. PubMed ID: 34655668
    [Abstract] [Full Text] [Related]

  • 2. Saikosaponin B4 Suppression Cancer Progression by Inhibiting SW480 and SW620 Cells Proliferation via the PI3K/AKT/mTOR Pathway in Colon Cancer.
    Zhang Y, Lin L, Wang Y, Liu Z, Xia W, Sui H, Fu X.
    Curr Cancer Drug Targets; 2022 Jan 30; 22(11):889-903. PubMed ID: 35762543
    [Abstract] [Full Text] [Related]

  • 3. Anti-breast cancer and toxicity studies of total secondary saponin from Anemone raddeana Rhizome on MCF-7 cells via ROS generation and PI3K/AKT/mTOR inactivation.
    Zhang D, Zhang Q, Zheng Y, Lu J.
    J Ethnopharmacol; 2020 Sep 15; 259():112984. PubMed ID: 32446927
    [Abstract] [Full Text] [Related]

  • 4. Anti-proliferative effect of RCE-4 from Reineckia carnea on human cervical cancer HeLa cells by inhibiting the PI3K/Akt/mTOR signaling pathway and NF-κB activation.
    Bai C, Yang X, Zou K, He H, Wang J, Qin H, Yu X, Liu C, Zheng J, Cheng F, Chen J.
    Naunyn Schmiedebergs Arch Pharmacol; 2016 Jun 15; 389(6):573-84. PubMed ID: 26935715
    [Abstract] [Full Text] [Related]

  • 5. [Inhibition effect of active fraction from clove on PI3K/Akt/mTOR signaling pathway to induce apoptosis of human colon cancer HCT116 cells].
    Zhao G, Zhang D, Yang XH, Li XF, Liu MH.
    Zhongguo Zhong Yao Za Zhi; 2021 Mar 15; 46(5):1197-1204. PubMed ID: 33787115
    [Abstract] [Full Text] [Related]

  • 6. A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K/AKT signaling pathway.
    Lin F, Zhang G, Yang X, Wang M, Wang R, Wan M, Wang J, Wu B, Yan T, Jia Y.
    J Ethnopharmacol; 2023 Mar 01; 303():115933. PubMed ID: 36403742
    [Abstract] [Full Text] [Related]

  • 7. Mechanism of gypenosides of Gynostemma pentaphyllum inducing apoptosis of renal cell carcinoma by PI3K/AKT/mTOR pathway.
    Liu H, Li X, Duan Y, Xie JB, Piao XL.
    J Ethnopharmacol; 2021 May 10; 271():113907. PubMed ID: 33556477
    [Abstract] [Full Text] [Related]

  • 8. [Effect of total saponins from Panacis Majoris Rhizoma on proliferation, apoptosis and autophagy of human cervical carcinoma HeLa cells].
    Pang XY, Zhou R, Song RT, Li N, Wang YQ, Song ZX, Liu YR, Tang ZS.
    Zhongguo Zhong Yao Za Zhi; 2024 Jul 10; 49(14):3848-3856. PubMed ID: 39099358
    [Abstract] [Full Text] [Related]

  • 9. Total saponins of Bolbostemma paniculatum (maxim.) Franquet exert antitumor activity against MDA-MB-231 human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway.
    Dou JW, Shang RG, Lei XQ, Li KL, Guo ZZ, Ye K, Yang XJ, Li YW, Zhou YY, Yao J, Huang Q.
    BMC Complement Altern Med; 2019 Nov 08; 19(1):304. PubMed ID: 31703679
    [Abstract] [Full Text] [Related]

  • 10. PDB-1 from Potentilla discolor Bunge induces apoptosis and autophagy by downregulating the PI3K/Akt/mTOR signaling pathway in A549 cells.
    Zhang RR, Meng NN, Liu C, Li KL, Wang MX, Lv ZB, Chen SY, Guo X, Wang XK, Wang Q, Sun JY.
    Biomed Pharmacother; 2020 Sep 08; 129():110378. PubMed ID: 32544818
    [Abstract] [Full Text] [Related]

  • 11. Chloroform extract from Sophora Tonkinensis Gagnep. inhibit proliferation, migration, invasion and promote apoptosis of nasopharyngeal carcinoma cells by silencing the PI3K/AKT/mTOR signaling pathway.
    ShuoWang, Song Z, Gong X, Ou C, Zhang W, Wang J, Yao C, Qin S, Yan B, Li Q, Wei K, Hou X, Zhou X, Miao J.
    J Ethnopharmacol; 2021 May 10; 271():113879. PubMed ID: 33524509
    [Abstract] [Full Text] [Related]

  • 12. Deoxyshikonin isolated from Arnebia euchroma inhibits colorectal cancer by down-regulating the PI3K/Akt/mTOR pathway.
    Zhu Y, Zhong Y, Long X, Zhu Z, Zhou Y, Ye H, Zeng X, Zheng X.
    Pharm Biol; 2019 Dec 10; 57(1):412-423. PubMed ID: 31230505
    [Abstract] [Full Text] [Related]

  • 13. The role of c2orf68 and PI3K/Akt/mTOR pathway in human colorectal cancer.
    Wen X, Zhu J, Dong L, Chen Y.
    Med Oncol; 2014 Aug 10; 31(8):92. PubMed ID: 25023051
    [Abstract] [Full Text] [Related]

  • 14. Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K-AKT signaling pathway as revealed by network pharmacology and in vitro experimental verification.
    Wang Y, Chu F, Lin J, Li Y, Johnson N, Zhang J, Gai C, Su Z, Cheng H, Wang L, Ding X.
    J Ethnopharmacol; 2021 Oct 28; 279():114399. PubMed ID: 34246740
    [Abstract] [Full Text] [Related]

  • 15. PI3K/AKT/mTOR signaling is involved in (-)-epigallocatechin-3-gallate-induced apoptosis of human pancreatic carcinoma cells.
    Liu S, Wang XJ, Liu Y, Cui YF.
    Am J Chin Med; 2013 Oct 28; 41(3):629-42. PubMed ID: 23711146
    [Abstract] [Full Text] [Related]

  • 16. Effects of Glut1 gene silencing on proliferation, differentiation, and apoptosis of colorectal cancer cells by targeting the TGF-β/PI3K-AKT-mTOR signaling pathway.
    Wu XL, Wang LK, Yang DD, Qu M, Yang YJ, Guo F, Han L, Xue J.
    J Cell Biochem; 2018 Feb 28; 119(2):2356-2367. PubMed ID: 28884839
    [Abstract] [Full Text] [Related]

  • 17. Study on the molecular mechanism of nightshade in the treatment of colon cancer.
    Na S, Ying L, Jun C, Ya X, Suifeng Z, Yuxi H, Jing W, Zonglang L, Xiaojun Y, Yue W.
    Bioengineered; 2022 Jan 28; 13(1):1575-1589. PubMed ID: 35012428
    [Abstract] [Full Text] [Related]

  • 18. Long noncoding RNA-JPX predicts the poor prognosis of ovarian cancer patients and promotes tumor cell proliferation, invasion and migration by the PI3K/Akt/mTOR signaling pathway.
    Li J, Feng L, Tian C, Tang YL, Tang Y, Hu FQ.
    Eur Rev Med Pharmacol Sci; 2018 Dec 28; 22(23):8135-8144. PubMed ID: 30556851
    [Abstract] [Full Text] [Related]

  • 19. Naringin inhibits thyroid cancer cell proliferation and induces cell apoptosis through repressing PI3K/AKT pathway.
    Zhou J, Xia L, Zhang Y.
    Pathol Res Pract; 2019 Dec 28; 215(12):152707. PubMed ID: 31727500
    [Abstract] [Full Text] [Related]

  • 20. Erianin induces triple-negative breast cancer cells apoptosis by activating PI3K/Akt pathway.
    Xu Y, Fang R, Shao J, Cai Z.
    Biosci Rep; 2021 Jun 25; 41(6):. PubMed ID: 34036307
    [Abstract] [Full Text] [Related]

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