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Journal Abstract Search


215 related items for PubMed ID: 34762139

  • 1. DMSO-free highly differentiated HepaRG spheroids for chronic toxicity, liver functions and genotoxicity studies.
    Rose S, Cuvellier M, Ezan F, Carteret J, Bruyère A, Legagneux V, Nesslany F, Baffet G, Langouët S.
    Arch Toxicol; 2022 Jan; 96(1):243-258. PubMed ID: 34762139
    [Abstract] [Full Text] [Related]

  • 2. A DMSO-free hepatocyte maturation medium accelerates hepatic differentiation of HepaRG cells in vitro.
    Wang ZY, Li WJ, Li QG, Jing HS, Yuan TJ, Fu GB, Tang D, Zhang HD, Yan HX, Zhai B.
    Biomed Pharmacother; 2019 Aug; 116():109010. PubMed ID: 31136950
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  • 3. Adaptation of the in vitro micronucleus assay for genotoxicity testing using 3D liver models supporting longer-term exposure durations.
    Conway GE, Shah UK, Llewellyn S, Cervena T, Evans SJ, Al Ali AS, Jenkins GJ, Clift MJD, Doak SH.
    Mutagenesis; 2020 Sep 12; 35(4):319-330. PubMed ID: 32780103
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  • 4. HepaRG microencapsulated spheroids in DMSO-free culture: novel culturing approaches for enhanced xenobiotic and biosynthetic metabolism.
    Rebelo SP, Costa R, Estrada M, Shevchenko V, Brito C, Alves PM.
    Arch Toxicol; 2015 Aug 12; 89(8):1347-58. PubMed ID: 25107451
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  • 5. Assessment of the genotoxic potential of indirect chemical mutagens in HepaRG cells by the comet and the cytokinesis-block micronucleus assays.
    Le Hegarat L, Dumont J, Josse R, Huet S, Lanceleur R, Mourot A, Poul JM, Guguen-Guillouzo C, Guillouzo A, Fessard V.
    Mutagenesis; 2010 Nov 12; 25(6):555-60. PubMed ID: 20675360
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  • 6. Three-dimensional HepaRG spheroids as a liver model to study human genotoxicity in vitro with the single cell gel electrophoresis assay.
    Mandon M, Huet S, Dubreil E, Fessard V, Le Hégarat L.
    Sci Rep; 2019 Jul 22; 9(1):10548. PubMed ID: 31332230
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  • 7. Towards better prediction of xenobiotic genotoxicity: CometChip technology coupled with a 3D model of HepaRG human liver cells.
    Barranger A, Le Hégarat L.
    Arch Toxicol; 2022 Jul 22; 96(7):2087-2095. PubMed ID: 35419617
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  • 8. Comparison of Drug Metabolism and Its Related Hepatotoxic Effects in HepaRG, Cryopreserved Human Hepatocytes, and HepG2 Cell Cultures.
    Yokoyama Y, Sasaki Y, Terasaki N, Kawataki T, Takekawa K, Iwase Y, Shimizu T, Sanoh S, Ohta S.
    Biol Pharm Bull; 2018 May 01; 41(5):722-732. PubMed ID: 29445054
    [Abstract] [Full Text] [Related]

  • 9. An adaptation of the human HepaRG cells to the in vitro micronucleus assay.
    Jossé R, Rogue A, Lorge E, Guillouzo A.
    Mutagenesis; 2012 May 01; 27(3):295-304. PubMed ID: 22058015
    [Abstract] [Full Text] [Related]

  • 10. Liver-on-chip model and application in predictive genotoxicity and mutagenicity of drugs.
    Kopp B, Khawam A, Di Perna K, Lenart D, Vinette M, Silva R, Zanoni TB, Rore C, Guenigault G, Richardson E, Kostrzewski T, Boswell A, Van P, Valentine Iii C, Salk J, Hamel A.
    Mutat Res Genet Toxicol Environ Mutagen; 2024 May 01; 896():503762. PubMed ID: 38821675
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  • 12. High-throughput micronucleus assay using three-dimensional HepaRG spheroids for in vitro genotoxicity testing.
    Seo JE, Li X, Le Y, Mei N, Zhou T, Guo X.
    Arch Toxicol; 2023 Apr 01; 97(4):1163-1175. PubMed ID: 36847820
    [Abstract] [Full Text] [Related]

  • 13. Long-term functional stability of human HepaRG hepatocytes and use for chronic toxicity and genotoxicity studies.
    Jossé R, Aninat C, Glaise D, Dumont J, Fessard V, Morel F, Poul JM, Guguen-Guillouzo C, Guillouzo A.
    Drug Metab Dispos; 2008 Jun 01; 36(6):1111-8. PubMed ID: 18347083
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  • 16. Differentiation of the human liver progenitor cell line (HepaRG) on a microfluidic-based biochip.
    Jang M, Kleber A, Ruckelshausen T, Betzholz R, Manz A.
    J Tissue Eng Regen Med; 2019 Mar 01; 13(3):482-494. PubMed ID: 30746894
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  • 17. Evaluation of HepaRG cells as an in vitro model for human drug metabolism studies.
    Kanebratt KP, Andersson TB.
    Drug Metab Dispos; 2008 Jul 01; 36(7):1444-52. PubMed ID: 18385292
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