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258 related items for PubMed ID: 34815345

  • 1. Molecular structure of an open human KATP channel.
    Zhao C, MacKinnon R.
    Proc Natl Acad Sci U S A; 2021 Nov 30; 118(48):. PubMed ID: 34815345
    [Abstract] [Full Text] [Related]

  • 2. Molecular structure of human KATP in complex with ATP and ADP.
    Lee KPK, Chen J, MacKinnon R.
    Elife; 2017 Dec 29; 6():. PubMed ID: 29286281
    [Abstract] [Full Text] [Related]

  • 3. ATP binding without hydrolysis switches sulfonylurea receptor 1 (SUR1) to outward-facing conformations that activate KATP channels.
    Sikimic J, McMillen TS, Bleile C, Dastvan F, Quast U, Krippeit-Drews P, Drews G, Bryan J.
    J Biol Chem; 2019 Mar 08; 294(10):3707-3719. PubMed ID: 30587573
    [Abstract] [Full Text] [Related]

  • 4. Cryo-electron microscopy structures and progress toward a dynamic understanding of KATP channels.
    Puljung MC.
    J Gen Physiol; 2018 May 07; 150(5):653-669. PubMed ID: 29685928
    [Abstract] [Full Text] [Related]

  • 5. Dynamic duo: Kir6 and SUR in KATP channel structure and function.
    Patton BL, Zhu P, ElSheikh A, Driggers CM, Shyng SL.
    Channels (Austin); 2024 Dec 07; 18(1):2327708. PubMed ID: 38489043
    [Abstract] [Full Text] [Related]

  • 6. Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
    Wu JX, Ding D, Wang M, Kang Y, Zeng X, Chen L.
    Protein Cell; 2018 Jun 07; 9(6):553-567. PubMed ID: 29594720
    [Abstract] [Full Text] [Related]

  • 7. The Structural Basis for the Binding of Repaglinide to the Pancreatic KATP Channel.
    Ding D, Wang M, Wu JX, Kang Y, Chen L.
    Cell Rep; 2019 May 07; 27(6):1848-1857.e4. PubMed ID: 31067468
    [Abstract] [Full Text] [Related]

  • 8. Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating.
    Martin GM, Yoshioka C, Rex EA, Fay JF, Xie Q, Whorton MR, Chen JZ, Shyng SL.
    Elife; 2017 Jan 16; 6():. PubMed ID: 28092267
    [Abstract] [Full Text] [Related]

  • 9. Production and purification of ATP-sensitive potassium channel particles for cryo-electron microscopy.
    Driggers CM, Shyng SL.
    Methods Enzymol; 2021 Jan 16; 653():121-150. PubMed ID: 34099169
    [Abstract] [Full Text] [Related]

  • 10. Structure of an open KATP channel reveals tandem PIP2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.
    Driggers CM, Kuo YY, Zhu P, ElSheikh A, Shyng SL.
    Nat Commun; 2024 Mar 20; 15(1):2502. PubMed ID: 38509107
    [Abstract] [Full Text] [Related]

  • 11. Remodelling of the SUR-Kir6.2 interface of the KATP channel upon ATP binding revealed by the conformational blocker rhodamine 123.
    Hosy E, Dérand R, Revilloud J, Vivaudou M.
    J Physiol; 2007 Jul 01; 582(Pt 1):27-39. PubMed ID: 17510180
    [Abstract] [Full Text] [Related]

  • 12. Structure of a Pancreatic ATP-Sensitive Potassium Channel.
    Li N, Wu JX, Ding D, Cheng J, Gao N, Chen L.
    Cell; 2017 Jan 12; 168(1-2):101-110.e10. PubMed ID: 28086082
    [Abstract] [Full Text] [Related]

  • 13. Palmitoylation of the KATP channel Kir6.2 subunit promotes channel opening by regulating PIP2 sensitivity.
    Yang HQ, Martinez-Ortiz W, Hwang J, Fan X, Cardozo TJ, Coetzee WA.
    Proc Natl Acad Sci U S A; 2020 May 12; 117(19):10593-10602. PubMed ID: 32332165
    [Abstract] [Full Text] [Related]

  • 14. Two regions of sulfonylurea receptor specify the spontaneous bursting and ATP inhibition of KATP channel isoforms.
    Babenko AP, Gonzalez G, Bryan J.
    J Biol Chem; 1999 Apr 23; 274(17):11587-92. PubMed ID: 10206966
    [Abstract] [Full Text] [Related]

  • 15. Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM.
    Martin GM, Kandasamy B, DiMaio F, Yoshioka C, Shyng SL.
    Elife; 2017 Oct 24; 6():. PubMed ID: 29035201
    [Abstract] [Full Text] [Related]

  • 16. Conformational changes at cytoplasmic intersubunit interactions control Kir channel gating.
    Wang S, Borschel WF, Heyman S, Hsu P, Nichols CG.
    J Biol Chem; 2017 Jun 16; 292(24):10087-10096. PubMed ID: 28446610
    [Abstract] [Full Text] [Related]

  • 17. Syntaxin-1A inhibits cardiac KATP channels by its actions on nucleotide binding folds 1 and 2 of sulfonylurea receptor 2A.
    Kang Y, Leung YM, Manning-Fox JE, Xia F, Xie H, Sheu L, Tsushima RG, Light PE, Gaisano HY.
    J Biol Chem; 2004 Nov 05; 279(45):47125-31. PubMed ID: 15339904
    [Abstract] [Full Text] [Related]

  • 18. Vascular KATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides.
    Sung MW, Yang Z, Driggers CM, Patton BL, Mostofian B, Russo JD, Zuckerman DM, Shyng SL.
    Proc Natl Acad Sci U S A; 2021 Nov 02; 118(44):. PubMed ID: 34711681
    [Abstract] [Full Text] [Related]

  • 19. Proximal C-terminal domain of sulphonylurea receptor 2A interacts with pore-forming Kir6 subunits in KATP channels.
    Rainbow RD, James M, Hudman D, Al Johi M, Singh H, Watson PJ, Ashmole I, Davies NW, Lodwick D, Norman RI.
    Biochem J; 2004 Apr 01; 379(Pt 1):173-81. PubMed ID: 14672537
    [Abstract] [Full Text] [Related]

  • 20. Mechanistic insights on KATP channel regulation from cryo-EM structures.
    Driggers CM, Shyng SL.
    J Gen Physiol; 2023 Jan 02; 155(1):. PubMed ID: 36441147
    [Abstract] [Full Text] [Related]

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