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PUBMED FOR HANDHELDS

Journal Abstract Search


191 related items for PubMed ID: 34826216

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  • 2. Aberrant Sodium Channel Currents and Hyperexcitability of Medial Entorhinal Cortex Neurons in a Mouse Model of SCN8A Encephalopathy.
    Ottolini M, Barker BS, Gaykema RP, Meisler MH, Patel MK.
    J Neurosci; 2017 Aug 09; 37(32):7643-7655. PubMed ID: 28676574
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  • 3. The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy.
    Baker EM, Thompson CH, Hawkins NA, Wagnon JL, Wengert ER, Patel MK, George AL, Meisler MH, Kearney JA.
    Epilepsia; 2018 Jun 09; 59(6):1166-1176. PubMed ID: 29782051
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  • 7. Neuronal hyperexcitability in a mouse model of SCN8A epileptic encephalopathy.
    Lopez-Santiago LF, Yuan Y, Wagnon JL, Hull JM, Frasier CR, O'Malley HA, Meisler MH, Isom LL.
    Proc Natl Acad Sci U S A; 2017 Feb 28; 114(9):2383-2388. PubMed ID: 28193882
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  • 12. NBI-921352, a first-in-class, NaV1.6 selective, sodium channel inhibitor that prevents seizures in Scn8a gain-of-function mice, and wild-type mice and rats.
    Johnson JP, Focken T, Khakh K, Tari PK, Dube C, Goodchild SJ, Andrez JC, Bankar G, Bogucki D, Burford K, Chang E, Chowdhury S, Dean R, de Boer G, Decker S, Dehnhardt C, Feng M, Gong W, Grimwood M, Hasan A, Hussainkhel A, Jia Q, Lee S, Li J, Lin S, Lindgren A, Lofstrand V, Mezeyova J, Namdari R, Nelkenbrecher K, Shuart NG, Sojo L, Sun S, Taron M, Waldbrook M, Weeratunge D, Wesolowski S, Williams A, Wilson M, Xie Z, Yoo R, Young C, Zenova A, Zhang W, Cutts AJ, Sherrington RP, Pimstone SN, Winquist R, Cohen CJ, Empfield JR.
    Elife; 2022 Mar 02; 11():. PubMed ID: 35234610
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  • 13. The SCN8A encephalopathy mutation p.Ile1327Val displays elevated sensitivity to the anticonvulsant phenytoin.
    Barker BS, Ottolini M, Wagnon JL, Hollander RM, Meisler MH, Patel MK.
    Epilepsia; 2016 Sep 02; 57(9):1458-66. PubMed ID: 27375106
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  • 14. Clinical study of 19 patients with SCN8A-related epilepsy: Two modes of onset regarding EEG and seizures.
    Denis J, Villeneuve N, Cacciagli P, Mignon-Ravix C, Lacoste C, Lefranc J, Napuri S, Damaj L, Villega F, Pedespan JM, Moutton S, Mignot C, Doummar D, Lion-François L, Gataullina S, Dulac O, Martin M, Gueden S, Lesca G, Julia S, Cances C, Journel H, Altuzarra C, Ben Zeev B, Afenjar A, Barth M, Villard L, Milh M.
    Epilepsia; 2019 May 02; 60(5):845-856. PubMed ID: 31026061
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  • 15. Variant-specific changes in persistent or resurgent sodium current in SCN8A-related epilepsy patient-derived neurons.
    Tidball AM, Lopez-Santiago LF, Yuan Y, Glenn TW, Margolis JL, Clayton Walker J, Kilbane EG, Miller CA, Martina Bebin E, Scott Perry M, Isom LL, Parent JM.
    Brain; 2020 Oct 01; 143(10):3025-3040. PubMed ID: 32968789
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  • 19. Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.
    Makinson CD, Tanaka BS, Lamar T, Goldin AL, Escayg A.
    Neurobiol Dis; 2014 Aug 01; 68():16-25. PubMed ID: 24704313
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  • 20. Genotype-phenotype correlations in Polish patients with SCN8A-related epilepsy: A multicentre observational study.
    Paprocka J, Steinborn B, Krygier M, Winczewska-Wiktor A, Przyslo L, Hutny M, Hoffman-Zacharska D, Mazurkiewicz H, Kochanowska I, Zebrowska J, Zawadzka M, Piasecki L, Mazurkiewicz-Beldzinska M.
    Seizure; 2024 Aug 01; 120():201-209. PubMed ID: 39047613
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