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377 related items for PubMed ID: 3484542
1. 1-methyl-4-phenylpyridine is neurotoxic to the nigrostriatal dopamine pathway. Bradbury AJ, Costall B, Domeney AM, Jenner P, Kelly ME, Marsden CD, Naylor RJ. Nature; ; 319(6048):56-7. PubMed ID: 3484542 [Abstract] [Full Text] [Related]
3. The actions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in animals as a model of Parkinson's disease. Jenner P, Marsden CD. J Neural Transm Suppl; 1986; 20():11-39. PubMed ID: 3091760 [Abstract] [Full Text] [Related]
4. On the mechanisms underlying 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity: the effect of perinigral infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, its metabolite and their analogs in the rat. Harik SI, Schmidley JW, Iacofano LA, Blue P, Arora PK, Sayre LM. J Pharmacol Exp Ther; 1987 May; 241(2):669-76. PubMed ID: 2437293 [Abstract] [Full Text] [Related]
5. Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity. Heikkila RE, Nicklas WJ, Vyas I, Duvoisin RC. Neurosci Lett; 1985 Dec 18; 62(3):389-94. PubMed ID: 3912685 [Abstract] [Full Text] [Related]
9. Studies on the mechanism of the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Heikkila RE, Nicklas WJ, Duvoisin RC. Adv Neurol; 1987 Oct 18; 45():149-52. PubMed ID: 3103384 [No Abstract] [Full Text] [Related]
10. Effects of the parkinsonism-inducing neurotoxin MPTP and its metabolite MPP+ on sympathetic adrenergic nerves in mouse iris and atrium. Luthman J, Jonsson G. Med Biol; 1986 Oct 18; 64(2-3):95-102. PubMed ID: 3489145 [Abstract] [Full Text] [Related]
13. Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a radical scavenger, prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the substantia nigra but not the striatum. Kawasaki T, Ishihara K, Ago Y, Baba A, Matsuda T. J Pharmacol Exp Ther; 2007 Jul 18; 322(1):274-81. PubMed ID: 17429058 [Abstract] [Full Text] [Related]
14. Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. II. Evaluation of the biological activity of the pyridinium metabolites formed from the monoamine oxidase-catalyzed oxidation of MPTP analogs. Youngster SK, Nicklas WJ, Heikkila RE. J Pharmacol Exp Ther; 1989 Jun 18; 249(3):829-35. PubMed ID: 2786565 [Abstract] [Full Text] [Related]
16. Bioactivation of MPTP: reactive metabolites and possible biochemical sequelae. Trevor AJ, Castagnoli N, Caldera P, Ramsay RR, Singer TP. Life Sci; 1987 Feb 23; 40(8):713-9. PubMed ID: 3492651 [Abstract] [Full Text] [Related]
17. Development of fluorinated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs with potent nigrostriatal toxicity for potential use in positron emission tomography studies. Harik SI, Riachi NJ, Hritz MA, Berridge MS, Sayre LM. J Pharmacol Exp Ther; 1993 Aug 23; 266(2):790-5. PubMed ID: 8355208 [Abstract] [Full Text] [Related]
18. Effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its metabolite, N-methyl-4-phenylpyridinium ion, on dopaminergic nigrostriatal neurons in the mouse. Perry TL, Yong VW, Jones K, Wall RA, Clavier RM, Foulks JG, Wright JM. Neurosci Lett; 1985 Aug 05; 58(3):321-6. PubMed ID: 3876525 [Abstract] [Full Text] [Related]
19. In brown Norway rats, MPP+ is accumulated in the nigrostriatal dopaminergic terminals but it is not neurotoxic: a model of natural resistance to MPTP toxicity. Zuddas A, Fascetti F, Corsini GU, Piccardi MP. Exp Neurol; 1994 May 05; 127(1):54-61. PubMed ID: 8200437 [Abstract] [Full Text] [Related]
20. The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety. Bradbury AJ, Costall B, Domeney AM, Testa B, Jenner PG, Marsden CD, Naylor RJ. Neurosci Lett; 1985 Oct 24; 61(1-2):121-6. PubMed ID: 2417166 [Abstract] [Full Text] [Related] Page: [Next] [New Search]