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Journal Abstract Search

412 related items for PubMed ID: 34871841

  • 1. Design and synthesis of ciprofloxacin-sulfonamide hybrids to manipulate ciprofloxacin pharmacological qualities: Potency and side effects.
    Ibrahim NM, Fahim SH, Hassan M, Farag AE, Georgey HH.
    Eur J Med Chem; 2022 Jan 15; 228():114021. PubMed ID: 34871841
    [Abstract] [Full Text] [Related]

  • 2. Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study.
    Ibrahim TS, Almalki AJ, Moustafa AH, Allam RM, Abuo-Rahma GEA, El Subbagh HI, Mohamed MFA.
    Bioorg Chem; 2021 Jun 15; 111():104885. PubMed ID: 33838559
    [Abstract] [Full Text] [Related]

  • 3. Design, green one-pot synthesis and molecular docking study of novel N,N-bis(cyanoacetyl)hydrazines and bis-coumarins as effective inhibitors of DNA gyrase and topoisomerase IV.
    Metwally NH, Abdallah SO, Mohsen MMA.
    Bioorg Chem; 2020 Apr 15; 97():103672. PubMed ID: 32145481
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV.
    Hofny HA, Mohamed MFA, Gomaa HAM, Abdel-Aziz SA, Youssif BGM, El-Koussi NA, Aboraia AS.
    Bioorg Chem; 2021 Jul 15; 112():104920. PubMed ID: 33910078
    [Abstract] [Full Text] [Related]

  • 5. One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor.
    Salem MA, Ragab A, Askar AA, El-Khalafawy A, Makhlouf AH.
    Eur J Med Chem; 2020 Feb 15; 188():111977. PubMed ID: 31927313
    [Abstract] [Full Text] [Related]

  • 6. Thiazolidine-2,4-dione-linked ciprofloxacin derivatives with broad-spectrum antibacterial, MRSA and topoisomerase inhibitory activities.
    Aziz HA, El-Saghier AMM, Badr M, Abuo-Rahma GEA, Shoman ME.
    Mol Divers; 2022 Jun 15; 26(3):1743-1759. PubMed ID: 34455532
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis, molecular docking study, and antibacterial evaluation of some new fluoroquinolone analogues bearing a quinazolinone moiety.
    Norouzbahari M, Salarinejad S, Güran M, Şanlıtürk G, Emamgholipour Z, Bijanzadeh HR, Toolabi M, Foroumadi A.
    Daru; 2020 Dec 15; 28(2):661-672. PubMed ID: 33030668
    [Abstract] [Full Text] [Related]

  • 8. Synthesis of novel 2-aminobenzothiazole derivatives as potential antimicrobial agents with dual DNA gyrase/topoisomerase IV inhibition.
    Ismail MMF, Abdulwahab HG, Nossier ES, El Menofy NG, Abdelkhalek BA.
    Bioorg Chem; 2020 Jan 15; 94():103437. PubMed ID: 31812260
    [Abstract] [Full Text] [Related]

  • 9. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
    Kassab AE, Gedawy EM.
    Eur J Med Chem; 2018 Apr 25; 150():403-418. PubMed ID: 29547830
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, and characterization of novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram-positive activity.
    Surivet JP, Zumbrunn C, Rueedi G, Hubschwerlen C, Bur D, Bruyère T, Locher H, Ritz D, Keck W, Seiler P, Kohl C, Gauvin JC, Mirre A, Kaegi V, Dos Santos M, Gaertner M, Delers J, Enderlin-Paput M, Boehme M.
    J Med Chem; 2013 Sep 26; 56(18):7396-415. PubMed ID: 23968485
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents.
    Fedorowicz J, Sączewski J, Konopacka A, Waleron K, Lejnowski D, Ciura K, Tomašič T, Skok Ž, Savijoki K, Morawska M, Gilbert-Girard S, Fallarero A.
    Eur J Med Chem; 2019 Oct 01; 179():576-590. PubMed ID: 31279292
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, Antimicrobial Activity and Molecular Docking of Novel Thiourea Derivatives Tagged with Thiadiazole, Imidazole and Triazine Moieties as Potential DNA Gyrase and Topoisomerase IV Inhibitors.
    Hashem HE, Amr AEE, Nossier ES, Elsayed EA, Azmy EM.
    Molecules; 2020 Jun 15; 25(12):. PubMed ID: 32549386
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and structure-activity relationship studies of 4-arylthiosemicarbazides as topoisomerase IV inhibitors with Gram-positive antibacterial activity. Search for molecular basis of antibacterial activity of thiosemicarbazides.
    Siwek A, Stączek P, Stefańska J.
    Eur J Med Chem; 2011 Nov 15; 46(11):5717-26. PubMed ID: 21978836
    [Abstract] [Full Text] [Related]

  • 14. New potent ciprofloxacin-uracil conjugates as DNA gyrase and topoisomerase IV inhibitors against methicillin-resistant Staphylococcus aureus.
    Samir M, Ramadan M, Abdelrahman MH, Elbastawesy MAI, Halby HM, Abdel-Aziz M, Abuo-Rahma GEA.
    Bioorg Med Chem; 2022 Nov 01; 73():117004. PubMed ID: 36148773
    [Abstract] [Full Text] [Related]

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  • 16. Synthesis and molecular docking of new N4-piperazinyl ciprofloxacin hybrids as antimicrobial DNA gyrase inhibitors.
    Mohammed HHH, Ali DME, Badr M, Habib AGK, Mahmoud AM, Farhan SM, Gany SSHAE, Mohamad SA, Hayallah AM, Abbas SH, Abuo-Rahma GEA.
    Mol Divers; 2023 Aug 01; 27(4):1751-1765. PubMed ID: 36152132
    [Abstract] [Full Text] [Related]

  • 17. Novel Bacterial Topoisomerase Inhibitors with Potent Broad-Spectrum Activity against Drug-Resistant Bacteria.
    Charrier C, Salisbury AM, Savage VJ, Duffy T, Moyo E, Chaffer-Malam N, Ooi N, Newman R, Cheung J, Metzger R, McGarry D, Pichowicz M, Sigerson R, Cooper IR, Nelson G, Butler HS, Craighead M, Ratcliffe AJ, Best SA, Stokes NR.
    Antimicrob Agents Chemother; 2017 May 01; 61(5):. PubMed ID: 28223393
    [Abstract] [Full Text] [Related]

  • 18. An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors.
    Tiz DB, Skok Ž, Durcik M, Tomašič T, Mašič LP, Ilaš J, Zega A, Draskovits G, Révész T, Nyerges Á, Pál C, Cruz CD, Tammela P, Žigon D, Kikelj D, Zidar N.
    Eur J Med Chem; 2019 Apr 01; 167():269-290. PubMed ID: 30776691
    [Abstract] [Full Text] [Related]

  • 19. Quercetin diacylglycoside analogues showing dual inhibition of DNA gyrase and topoisomerase IV as novel antibacterial agents.
    Hossion AM, Zamami Y, Kandahary RK, Tsuchiya T, Ogawa W, Iwado A, Sasaki K.
    J Med Chem; 2011 Jun 09; 54(11):3686-703. PubMed ID: 21534606
    [Abstract] [Full Text] [Related]

  • 20. Search for factors affecting antibacterial activity and toxicity of 1,2,4-triazole-ciprofloxacin hybrids.
    Plech T, Kaproń B, Paneth A, Kosikowska U, Malm A, Strzelczyk A, Stączek P, Świątek Ł, Rajtar B, Polz-Dacewicz M.
    Eur J Med Chem; 2015 Jun 05; 97():94-103. PubMed ID: 25951434
    [Abstract] [Full Text] [Related]

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