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Journal Abstract Search


157 related items for PubMed ID: 3488406

  • 1. Characterization of the neurotoxic potential of m-methoxy-MPTP and the use of its N-ethyl analogue as a means of avoiding exposure to a possible Parkinsonism-causing agent.
    Zimmerman DM, Cantrell BE, Reel JK, Hemrick-Luecke SK, Fuller RW.
    J Med Chem; 1986 Aug; 29(8):1517-20. PubMed ID: 3488406
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  • 2. Synthesis and toxicity toward nigrostriatal dopamine neurons of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) analogues.
    Fries DS, de Vries J, Hazelhoff B, Horn AS.
    J Med Chem; 1986 Mar; 29(3):424-7. PubMed ID: 3485197
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  • 3. Persistent depletion of striatal dopamine and its metabolites in mice by TMMP, an analogue of MPTP.
    Fuller RW, Hemrick-Luecke SK.
    J Pharm Pharmacol; 1987 Aug; 39(8):667-9. PubMed ID: 2888865
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  • 4. Evaluation of the biological activity of several analogs of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Youngster SK, Sonsalla PK, Heikkila RE.
    J Neurochem; 1987 Mar; 48(3):929-34. PubMed ID: 3492590
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  • 5. Persistent depletion of striatal dopamine in mice by m-hydroxy-MPTP.
    Fuller RW, Hemrick-Luecke SK.
    Res Commun Chem Pathol Pharmacol; 1986 Aug; 53(2):167-72. PubMed ID: 3764080
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  • 6. Persistent depletion of striatal dopamine in mice by 1-methyl-4-(2-thienyl)-1,2,3,6-tetrahydropyridine (MTTP).
    Fuller RW, Robertson DW, Hemrick-Luecke SK.
    Biochem Pharmacol; 1986 Jan 15; 35(2):143-4. PubMed ID: 3484628
    [No Abstract] [Full Text] [Related]

  • 7. Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity in mouse brain by piroheptine and trihexyphenidyl.
    Saitoh T.
    J Neurol Sci; 1988 Feb 15; 83(2-3):161-6. PubMed ID: 3258627
    [Abstract] [Full Text] [Related]

  • 8. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration to C57-black mice leads to parallel decrements in neostriatal dopamine content and tyrosine hydroxylase activity.
    Mayer RA, Walters AS, Heikkila RE.
    Eur J Pharmacol; 1986 Jan 29; 120(3):375-7. PubMed ID: 2868908
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  • 9. Characterization of hepatic microsomal metabolism as an in vivo detoxication pathway of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
    Chiba K, Kubota E, Miyakawa T, Kato Y, Ishizaki T.
    J Pharmacol Exp Ther; 1988 Sep 29; 246(3):1108-15. PubMed ID: 3262153
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  • 10. A high dose of MPTP overcomes the protective effect of selegiline against dopaminergic neurotoxicity.
    Fuller RW, Hemrick-Luecke SK.
    J Pharm Pharmacol; 1989 Jul 29; 41(7):492-3. PubMed ID: 2570859
    [Abstract] [Full Text] [Related]

  • 11. Differential neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in Swiss-Webster mice from different sources.
    Heikkila RE.
    Eur J Pharmacol; 1985 Oct 29; 117(1):131-3. PubMed ID: 3878793
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  • 18. The development of amine substituted analogues of MPTP as unique tools for the study of MPTP toxicity and Parkinson's disease.
    Johannessen JN, Savitt JM, Markey CJ, Bacon JP, Weisz A, Hanselman DS, Markey SP.
    Life Sci; 1987 Feb 23; 40(8):697-704. PubMed ID: 2433563
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  • 19. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) does not destroy nigrostriatal neurons in the scorbutic guinea pig.
    Perry TL, Yong VW, Ito M, Jones K, Wall RA, Foulks JG, Wright JM, Kish SJ.
    Life Sci; 1985 Apr 01; 36(13):1233-8. PubMed ID: 2858797
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  • 20. Endogenous analogs of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: indoleamine derived tetrahydro-beta-carbolines as potential causative factors in Parkinson's disease.
    Collins MA, Neafsey EJ, Cheng BY, Hurley-Gius K, Ung-Chhun NA, Pronger DA, Christensen MA, Hurley-Gius D.
    Adv Neurol; 1987 Apr 01; 45():179-82. PubMed ID: 3493625
    [No Abstract] [Full Text] [Related]


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