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167 related items for PubMed ID: 3488484

  • 1. Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP.
    Ramsay RR, Dadgar J, Trevor A, Singer TP.
    Life Sci; 1986 Aug 18; 39(7):581-8. PubMed ID: 3488484
    [Abstract] [Full Text] [Related]

  • 2. Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, by mitochondria.
    Ramsay RR, Singer TP.
    J Biol Chem; 1986 Jun 15; 261(17):7585-7. PubMed ID: 3486869
    [Abstract] [Full Text] [Related]

  • 3. Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium.
    Vyas I, Heikkila RE, Nicklas WJ.
    J Neurochem; 1986 May 15; 46(5):1501-7. PubMed ID: 3485701
    [Abstract] [Full Text] [Related]

  • 4. Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+.
    Ramsay RR, Salach JI, Singer TP.
    Biochem Biophys Res Commun; 1986 Jan 29; 134(2):743-8. PubMed ID: 2868716
    [Abstract] [Full Text] [Related]

  • 5. N-methyl-4-phenylpyridine (MMP+) together with 6-hydroxydopamine or dopamine stimulates Ca2+ release from mitochondria.
    Frei B, Richter C.
    FEBS Lett; 1986 Mar 17; 198(1):99-102. PubMed ID: 3082673
    [Abstract] [Full Text] [Related]

  • 6. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), its metabolite cyperquat (MPP+) and energy transduction in mitochondria from rat striatum and liver.
    Thakar JH, Hassan MN, Grimes JD.
    Prog Neuropsychopharmacol Biol Psychiatry; 1988 Mar 17; 12(2-3):355-62. PubMed ID: 3260387
    [Abstract] [Full Text] [Related]

  • 7. Dopamine-releasing action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridine (MPP+) in the neostriatum of the rat as demonstrated in vivo by the push-pull perfusion technique: dependence on sodium but not calcium ions.
    Sirinathsinghji DJ, Heavens RP, McBride CS.
    Brain Res; 1988 Mar 08; 443(1-2):101-16. PubMed ID: 3258784
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism.
    Ramsay RR, Salach JI, Dadgar J, Singer TP.
    Biochem Biophys Res Commun; 1986 Feb 26; 135(1):269-75. PubMed ID: 3485428
    [Abstract] [Full Text] [Related]

  • 9. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine inhibits proton motive force in energized liver mitochondria.
    Singh Y, Bhatnagar R, Sidhu GS, Batra JK, Krishna G.
    Arch Biochem Biophys; 1989 May 15; 271(1):217-22. PubMed ID: 2540715
    [Abstract] [Full Text] [Related]

  • 10. Bioactivation of MPTP: reactive metabolites and possible biochemical sequelae.
    Trevor AJ, Castagnoli N, Caldera P, Ramsay RR, Singer TP.
    Life Sci; 1987 Feb 23; 40(8):713-9. PubMed ID: 3492651
    [Abstract] [Full Text] [Related]

  • 11. Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes.
    Chiba K, Trevor AJ, Castagnoli N.
    Biochem Biophys Res Commun; 1985 May 16; 128(3):1228-32. PubMed ID: 3873939
    [Abstract] [Full Text] [Related]

  • 12. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain.
    Mizuno Y, Sone N, Saitoh T.
    J Neurochem; 1987 Jun 16; 48(6):1787-93. PubMed ID: 3106573
    [Abstract] [Full Text] [Related]

  • 13. MPTP, MPP+ and mitochondrial function.
    Nicklas WJ, Youngster SK, Kindt MV, Heikkila RE.
    Life Sci; 1987 Feb 23; 40(8):721-9. PubMed ID: 3100899
    [Abstract] [Full Text] [Related]

  • 14. Mechanism of the neurotoxicity of 1-methyl-4-phenylpyridinium (MPP+), the toxic bioactivation product of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Singer TP, Ramsay RR, McKeown K, Trevor A, Castagnoli NE.
    Toxicology; 1988 Apr 23; 49(1):17-23. PubMed ID: 3287690
    [Abstract] [Full Text] [Related]

  • 15. Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.
    Heikkila RE, Nicklas WJ, Vyas I, Duvoisin RC.
    Neurosci Lett; 1985 Dec 18; 62(3):389-94. PubMed ID: 3912685
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.
    Nicklas WJ, Vyas I, Heikkila RE.
    Life Sci; 1985 Jul 01; 36(26):2503-8. PubMed ID: 2861548
    [Abstract] [Full Text] [Related]

  • 17. MPP+-induced increases in extracellular potassium ion activity in rat striatal slices suggest that consequences of MPP+ neurotoxicity are spread beyond dopaminergic terminals.
    Hollinden GE, Sanchez-Ramos JR, Sick TJ, Rosenthal M.
    Brain Res; 1988 Dec 20; 475(2):283-90. PubMed ID: 3265070
    [Abstract] [Full Text] [Related]

  • 18. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), cyperquat (MPP+) and paraquat on isolated mitochondria from rat striatum, cortex and liver.
    Thakar JH, Hassan MN.
    Life Sci; 1988 Dec 20; 43(2):143-9. PubMed ID: 3260653
    [Abstract] [Full Text] [Related]

  • 19. Mitochondrial and metabolic toxicity of 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine.
    Kindt MV, Heikkila RE, Nicklas WJ.
    J Pharmacol Exp Ther; 1987 Sep 20; 242(3):858-63. PubMed ID: 3498818
    [Abstract] [Full Text] [Related]

  • 20. The neurotoxins 1-methyl-4-phenylpyridinium and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine are substrates for the organic cation transporter in renal brush border membrane vesicles.
    Sokol PP, Holohan PD, Ross CR.
    J Pharmacol Exp Ther; 1987 Jul 20; 242(1):152-7. PubMed ID: 2956410
    [Abstract] [Full Text] [Related]


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