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Journal Abstract Search


127 related items for PubMed ID: 3491879

  • 1. Characterization of the binding of N-methyl-4-phenylpyridine, the toxic metabolite of the parkinsonian neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, to neuromelanin.
    D'Amato RJ, Benham DF, Snyder SH.
    J Neurochem; 1987 Feb; 48(2):653-8. PubMed ID: 3491879
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  • 2. Selectivity of the parkinsonian neurotoxin MPTP: toxic metabolite MPP+ binds to neuromelanin.
    D'Amato RJ, Lipman ZP, Snyder SH.
    Science; 1986 Feb 28; 231(4741):987-9. PubMed ID: 3080808
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  • 3. Neuromelanin: a role in MPTP-induced neurotoxicity.
    D'Amato RJ, Alexander GM, Schwartzman RJ, Kitt CA, Price DL, Snyder SH.
    Life Sci; 1987 Feb 23; 40(8):705-12. PubMed ID: 2880274
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  • 4. 1-Methyl-4-phenylpyridinium ion (MPP+): identification of a metabolite of MPTP, a toxin selective to the substantia nigra.
    Langston JW, Irwin I, Langston EB, Forno LS.
    Neurosci Lett; 1984 Jul 13; 48(1):87-92. PubMed ID: 6332288
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  • 6. Selective accumulation of MPP+ in the substantia nigra: a key to neurotoxicity?
    Irwin I, Langston JW.
    Life Sci; 1985 Jan 21; 36(3):207-12. PubMed ID: 3871240
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  • 10. Oxygen activation during the interaction between MPTP metabolites and synthetic neuromelanin--an ESR-spin trapping, optical, and oxidase electrode study.
    Korytowski W, Felix CC, Kalyanaraman B.
    Biochem Biophys Res Commun; 1988 Jul 29; 154(2):781-8. PubMed ID: 2840906
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  • 11. Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease.
    Hirsch E, Graybiel AM, Agid YA.
    Nature; 1988 Jul 28; 334(6180):345-8. PubMed ID: 2899295
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  • 12. The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety.
    Bradbury AJ, Costall B, Domeney AM, Testa B, Jenner PG, Marsden CD, Naylor RJ.
    Neurosci Lett; 1985 Oct 24; 61(1-2):121-6. PubMed ID: 2417166
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  • 13. Astrocytes convert the parkinsonism inducing neurotoxin, MPTP, to its active metabolite, MPP+.
    Ransom BR, Kunis DM, Irwin I, Langston JW.
    Neurosci Lett; 1987 Apr 10; 75(3):323-8. PubMed ID: 3495754
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  • 14. Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes.
    Chiba K, Trevor AJ, Castagnoli N.
    Biochem Biophys Res Commun; 1985 May 16; 128(3):1228-32. PubMed ID: 3873939
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  • 15. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on ultrastructure of nigral neuromelanin in Macaca fascicularis.
    Levi AC, DeMattei M, Ravazzani R, Corvetti G, Golden GT, Fariello RG.
    Neurosci Lett; 1989 Jan 30; 96(3):271-6. PubMed ID: 2785665
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  • 16. Neuromelanin synthesis in rat and human substantia nigra.
    Rabey JM, Hefti F.
    J Neural Transm Park Dis Dement Sect; 1990 Jan 30; 2(1):1-14. PubMed ID: 2357268
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  • 17. Pargyline prevents MPTP-induced parkinsonism in primates.
    Langston JW, Irwin I, Langston EB, Forno LS.
    Science; 1984 Sep 28; 225(4669):1480-2. PubMed ID: 6332378
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  • 18. The importance of the '4-5' double bond for neurotoxicity in primates of the pyridine derivative MPTP.
    Langston JW, Irwin I, Langston EB, Forno LS.
    Neurosci Lett; 1984 Sep 07; 50(1-3):289-94. PubMed ID: 6333656
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  • 19. Quantification of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion in brain tissue by gas chromatography/mass spectrometry.
    Shih MC, Markey SP.
    Biomed Environ Mass Spectrom; 1986 Feb 07; 13(2):85-9. PubMed ID: 2937483
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  • 20. 1-methyl-4-phenylpyridine is neurotoxic to the nigrostriatal dopamine pathway.
    Bradbury AJ, Costall B, Domeney AM, Jenner P, Kelly ME, Marsden CD, Naylor RJ.
    Nature; 1986 Feb 07; 319(6048):56-7. PubMed ID: 3484542
    [Abstract] [Full Text] [Related]


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