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Journal Abstract Search

148 related items for PubMed ID: 34928138

  • 1. Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes.
    Ayoub A, Park SH, Lee YT, Cho US, Dou Y.
    Biochemistry; 2022 Jan 04; 61(1):1-9. PubMed ID: 34928138
    [Abstract] [Full Text] [Related]

  • 2. Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
    Park SH, Ayoub A, Lee YT, Xu J, Kim H, Zheng W, Zhang B, Sha L, An S, Zhang Y, Cianfrocco MA, Su M, Dou Y, Cho US.
    Nat Commun; 2019 Dec 05; 10(1):5540. PubMed ID: 31804488
    [Abstract] [Full Text] [Related]

  • 3. Structural basis of nucleosome recognition and modification by MLL methyltransferases.
    Xue H, Yao T, Cao M, Zhu G, Li Y, Yuan G, Chen Y, Lei M, Huang J.
    Nature; 2019 Sep 05; 573(7774):445-449. PubMed ID: 31485071
    [Abstract] [Full Text] [Related]

  • 4. Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.
    Patel A, Vought VE, Swatkoski S, Viggiano S, Howard B, Dharmarajan V, Monteith KE, Kupakuwana G, Namitz KE, Shinsky SA, Cotter RJ, Cosgrove MS.
    J Biol Chem; 2014 Jan 10; 289(2):868-84. PubMed ID: 24235145
    [Abstract] [Full Text] [Related]

  • 5. The internal interaction in RBBP5 regulates assembly and activity of MLL1 methyltransferase complex.
    Han J, Li T, Li Y, Li M, Wang X, Peng C, Su C, Li N, Li Y, Xu Y, Chen Y.
    Nucleic Acids Res; 2019 Nov 04; 47(19):10426-10438. PubMed ID: 31544921
    [Abstract] [Full Text] [Related]

  • 6. The Core Complex of Yeast COMPASS and Human Mixed-Lineage Leukemia (MLL), Structure, Function, and Recognition of the Nucleosome.
    Cho US.
    Subcell Biochem; 2024 Nov 04; 104():101-117. PubMed ID: 38963485
    [Abstract] [Full Text] [Related]

  • 7. On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.
    Patel A, Dharmarajan V, Vought VE, Cosgrove MS.
    J Biol Chem; 2009 Sep 04; 284(36):24242-56. PubMed ID: 19556245
    [Abstract] [Full Text] [Related]

  • 8. A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complex.
    Patel A, Vought VE, Dharmarajan V, Cosgrove MS.
    J Biol Chem; 2011 Feb 04; 286(5):3359-69. PubMed ID: 21106533
    [Abstract] [Full Text] [Related]

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  • 10. Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes.
    Wiersma M, Bussiere M, Halsall JA, Turan N, Slany R, Turner BM, Nightingale KP.
    Epigenetics Chromatin; 2016 Feb 04; 9():52. PubMed ID: 27895715
    [Abstract] [Full Text] [Related]

  • 11. Structural insights on the KMT2-NCP interaction.
    Yang Z, Zepeda R, Dou Y.
    Biochem Soc Trans; 2023 Feb 27; 51(1):427-434. PubMed ID: 36695549
    [Abstract] [Full Text] [Related]

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  • 13. Histone H3K18 & H3K23 acetylation directs establishment of MLL-mediated H3K4 methylation.
    Fox GC, Poncha KF, Smith BR, van der Maas LN, Robbins NN, Graham B, Dowen JM, Strahl BD, Young NL, Jain K.
    J Biol Chem; 2024 Aug 27; 300(8):107527. PubMed ID: 38960040
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  • 15. Regulation of MLL1 H3K4 methyltransferase activity by its core components.
    Dou Y, Milne TA, Ruthenburg AJ, Lee S, Lee JW, Verdine GL, Allis CD, Roeder RG.
    Nat Struct Mol Biol; 2006 Aug 27; 13(8):713-9. PubMed ID: 16878130
    [Abstract] [Full Text] [Related]

  • 16. Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
    Dharmarajan V, Lee JH, Patel A, Skalnik DG, Cosgrove MS.
    J Biol Chem; 2012 Aug 10; 287(33):27275-89. PubMed ID: 22665483
    [Abstract] [Full Text] [Related]

  • 17. High-affinity small molecular blockers of mixed lineage leukemia 1 (MLL1)-WDR5 interaction inhibit MLL1 complex H3K4 methyltransferase activity.
    Li DD, Chen WL, Wang ZH, Xie YY, Xu XL, Jiang ZY, Zhang XJ, You QD, Guo XK.
    Eur J Med Chem; 2016 Nov 29; 124():480-489. PubMed ID: 27598236
    [Abstract] [Full Text] [Related]

  • 18. Mixed lineage leukemia: a structure-function perspective of the MLL1 protein.
    Cosgrove MS, Patel A.
    FEBS J; 2010 Apr 29; 277(8):1832-42. PubMed ID: 20236310
    [Abstract] [Full Text] [Related]

  • 19. Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.
    Wang P, Lin C, Smith ER, Guo H, Sanderson BW, Wu M, Gogol M, Alexander T, Seidel C, Wiedemann LM, Ge K, Krumlauf R, Shilatifard A.
    Mol Cell Biol; 2009 Nov 29; 29(22):6074-85. PubMed ID: 19703992
    [Abstract] [Full Text] [Related]

  • 20. Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide.
    Patel A, Dharmarajan V, Cosgrove MS.
    J Biol Chem; 2008 Nov 21; 283(47):32158-61. PubMed ID: 18829459
    [Abstract] [Full Text] [Related]

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