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186 related items for PubMed ID: 34933885
1. Contributions of Cathepsin A and Carboxylesterase 1 to the Hydrolysis of Tenofovir Alafenamide in the Human Liver, and the Effect of CES1 Genetic Variation on Tenofovir Alafenamide Hydrolysis. Li J, Shi J, Xiao J, Tran L, Wang X, Zhu HJ. Drug Metab Dispos; 2022 Mar; 50(3):243-248. PubMed ID: 34933885 [Abstract] [Full Text] [Related]
2. Intracellular Activation of Tenofovir Alafenamide and the Effect of Viral and Host Protease Inhibitors. Birkus G, Bam RA, Willkom M, Frey CR, Tsai L, Stray KM, Yant SR, Cihlar T. Antimicrob Agents Chemother; 2016 Jan; 60(1):316-22. PubMed ID: 26503655 [Abstract] [Full Text] [Related]
3. Activation of Tenofovir Alafenamide and Sofosbuvir in the Human Lung and Its Implications in the Development of Nucleoside/Nucleotide Prodrugs for Treating SARS-CoV-2 Pulmonary Infection. Li J, Liu S, Shi J, Zhu HJ. Pharmaceutics; 2021 Oct 11; 13(10):. PubMed ID: 34683949 [Abstract] [Full Text] [Related]
8. Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977. Murakami E, Tolstykh T, Bao H, Niu C, Steuer HM, Bao D, Chang W, Espiritu C, Bansal S, Lam AM, Otto MJ, Sofia MJ, Furman PA. J Biol Chem; 2010 Nov 05; 285(45):34337-47. PubMed ID: 20801890 [Abstract] [Full Text] [Related]
9. Implications of efficient hepatic delivery by tenofovir alafenamide (GS-7340) for hepatitis B virus therapy. Murakami E, Wang T, Park Y, Hao J, Lepist EI, Babusis D, Ray AS. Antimicrob Agents Chemother; 2015 Nov 05; 59(6):3563-9. PubMed ID: 25870059 [Abstract] [Full Text] [Related]
10. The influence of carboxylesterase 1 polymorphism and cannabidiol on the hepatic metabolism of heroin. Qian Y, Gilliland TK, Markowitz JS. Chem Biol Interact; 2020 Jan 25; 316():108914. PubMed ID: 31837295 [Abstract] [Full Text] [Related]
12. CES1 genetic variation affects the activation of angiotensin-converting enzyme inhibitors. Wang X, Wang G, Shi J, Aa J, Comas R, Liang Y, Zhu HJ. Pharmacogenomics J; 2016 Jun 25; 16(3):220-30. PubMed ID: 26076923 [Abstract] [Full Text] [Related]
13. Association of Oseltamivir Activation with Gender and Carboxylesterase 1 Genetic Polymorphisms. Shi J, Wang X, Eyler RF, Liang Y, Liu L, Mueller BA, Zhu HJ. Basic Clin Pharmacol Toxicol; 2016 Dec 25; 119(6):555-561. PubMed ID: 27228223 [Abstract] [Full Text] [Related]
14. In vitro evaluation of the impact of Covid-19 therapeutic agents on the hydrolysis of the antiviral prodrug remdesivir. Zhang Q, Melchert PW, Markowitz JS. Chem Biol Interact; 2022 Sep 25; 365():110097. PubMed ID: 35964681 [Abstract] [Full Text] [Related]
15. Optimal pH 8.5 to 9 for the hydrolysis of vixotrigine and other basic substrates of carboxylesterase-1 in human liver microsomes. Johnson JL, Huang J, Rooney M, Gu C. Xenobiotica; 2022 Feb 25; 52(2):105-112. PubMed ID: 34904522 [Abstract] [Full Text] [Related]
16. Examination of the carboxylesterase phenotype in human liver. Ross MK, Borazjani A, Wang R, Crow JA, Xie S. Arch Biochem Biophys; 2012 Jun 01; 522(1):44-56. PubMed ID: 22525521 [Abstract] [Full Text] [Related]
17. Carboxylesterase 1 as a determinant of clopidogrel metabolism and activation. Zhu HJ, Wang X, Gawronski BE, Brinda BJ, Angiolillo DJ, Markowitz JS. J Pharmacol Exp Ther; 2013 Mar 01; 344(3):665-72. PubMed ID: 23275066 [Abstract] [Full Text] [Related]
18. Impact of carboxylesterase 1 genetic polymorphism on trandolapril activation in human liver and the pharmacokinetics and pharmacodynamics in healthy volunteers. Wang X, Her L, Xiao J, Shi J, Wu AH, Bleske BE, Zhu HJ. Clin Transl Sci; 2021 Jul 01; 14(4):1380-1389. PubMed ID: 33660934 [Abstract] [Full Text] [Related]
19. Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril. Zhu HJ, Appel DI, Johnson JA, Chavin KD, Markowitz JS. Biochem Pharmacol; 2009 Apr 01; 77(7):1266-72. PubMed ID: 19185566 [Abstract] [Full Text] [Related]
20. Identification of carboxylesterase-dependent dabigatran etexilate hydrolysis. Laizure SC, Parker RB, Herring VL, Hu ZY. Drug Metab Dispos; 2014 Feb 01; 42(2):201-6. PubMed ID: 24212379 [Abstract] [Full Text] [Related] Page: [Next] [New Search]