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568 related items for PubMed ID: 3493827

  • 1. Aging and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced degeneration of dopaminergic neurons in the substantia nigra.
    Ricaurte GA, Irwin I, Forno LS, DeLanney LE, Langston E, Langston JW.
    Brain Res; 1987 Feb 10; 403(1):43-51. PubMed ID: 3493827
    [Abstract] [Full Text] [Related]

  • 2. Fate of nigrostriatal neurons in young mature mice given 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: a neurochemical and morphological reassessment.
    Ricaurte GA, Langston JW, Delanney LE, Irwin I, Peroutka SJ, Forno LS.
    Brain Res; 1986 Jun 18; 376(1):117-24. PubMed ID: 3487376
    [Abstract] [Full Text] [Related]

  • 3. Age-related severity of dopaminergic neurodegeneration to MPTP neurotoxicity causes motor dysfunction in C57BL/6 mice.
    Ohashi S, Mori A, Kurihara N, Mitsumoto Y, Nakai M.
    Neurosci Lett; 2006 Jun 19; 401(1-2):183-7. PubMed ID: 16581184
    [Abstract] [Full Text] [Related]

  • 4. Effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its metabolite, N-methyl-4-phenylpyridinium ion, on dopaminergic nigrostriatal neurons in the mouse.
    Perry TL, Yong VW, Jones K, Wall RA, Clavier RM, Foulks JG, Wright JM.
    Neurosci Lett; 1985 Aug 05; 58(3):321-6. PubMed ID: 3876525
    [Abstract] [Full Text] [Related]

  • 5. CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons In vivo.
    Saporito MS, Brown EM, Miller MS, Carswell S.
    J Pharmacol Exp Ther; 1999 Feb 05; 288(2):421-7. PubMed ID: 9918541
    [Abstract] [Full Text] [Related]

  • 6. Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity.
    Przedborski S, Kostic V, Jackson-Lewis V, Naini AB, Simonetti S, Fahn S, Carlson E, Epstein CJ, Cadet JL.
    J Neurosci; 1992 May 05; 12(5):1658-67. PubMed ID: 1578260
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  • 7. The actions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in animals as a model of Parkinson's disease.
    Jenner P, Marsden CD.
    J Neural Transm Suppl; 1986 May 05; 20():11-39. PubMed ID: 3091760
    [Abstract] [Full Text] [Related]

  • 8. Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity.
    Przedborski S, Jackson-Lewis V, Yokoyama R, Shibata T, Dawson VL, Dawson TM.
    Proc Natl Acad Sci U S A; 1996 May 14; 93(10):4565-71. PubMed ID: 8643444
    [Abstract] [Full Text] [Related]

  • 9. Catalpol attenuates MPTP induced neuronal degeneration of nigral-striatal dopaminergic pathway in mice through elevating glial cell derived neurotrophic factor in striatum.
    Xu G, Xiong Z, Yong Y, Wang Z, Ke Z, Xia Z, Hu Y.
    Neuroscience; 2010 Apr 28; 167(1):174-84. PubMed ID: 20123001
    [Abstract] [Full Text] [Related]

  • 10. EGb761 protects against nigrostriatal dopaminergic neurotoxicity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice: role of oxidative stress.
    Rojas P, Serrano-García N, Mares-Sámano JJ, Medina-Campos ON, Pedraza-Chaverri J, Ogren SO.
    Eur J Neurosci; 2008 Jul 28; 28(1):41-50. PubMed ID: 18662333
    [Abstract] [Full Text] [Related]

  • 11. Immunity of fetal mice to prenatal administration of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Melamed E, Rosenthal J, Youdim MB.
    J Neurochem; 1990 Oct 28; 55(4):1427-31. PubMed ID: 2398363
    [Abstract] [Full Text] [Related]

  • 12. 1-Methyl-4-phenylpyridinium ion (MPP+): identification of a metabolite of MPTP, a toxin selective to the substantia nigra.
    Langston JW, Irwin I, Langston EB, Forno LS.
    Neurosci Lett; 1984 Jul 13; 48(1):87-92. PubMed ID: 6332288
    [Abstract] [Full Text] [Related]

  • 13. Early signs of neuronal apoptosis in the substantia nigra pars compacta of the progressive neurodegenerative mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model of Parkinson's disease.
    Novikova L, Garris BL, Garris DR, Lau YS.
    Neuroscience; 2006 Jun 19; 140(1):67-76. PubMed ID: 16533572
    [Abstract] [Full Text] [Related]

  • 14. Expression of c-Jun in dopaminergic neurons of the substantia nigra in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice.
    Nishi K.
    Brain Res; 1997 Oct 10; 771(1):133-41. PubMed ID: 9383016
    [Abstract] [Full Text] [Related]

  • 15. Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes.
    Chiba K, Trevor AJ, Castagnoli N.
    Biochem Biophys Res Commun; 1985 May 16; 128(3):1228-32. PubMed ID: 3873939
    [Abstract] [Full Text] [Related]

  • 16. Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.
    Heikkila RE, Nicklas WJ, Vyas I, Duvoisin RC.
    Neurosci Lett; 1985 Dec 18; 62(3):389-94. PubMed ID: 3912685
    [Abstract] [Full Text] [Related]

  • 17. Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
    Battaglia G, Busceti CL, Molinaro G, Biagioni F, Storto M, Fornai F, Nicoletti F, Bruno V.
    J Neurosci; 2004 Jan 28; 24(4):828-35. PubMed ID: 14749427
    [Abstract] [Full Text] [Related]

  • 18. Activated microglia affect the nigro-striatal dopamine neurons differently in neonatal and aged mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Sawada H, Hishida R, Hirata Y, Ono K, Suzuki H, Muramatsu S, Nakano I, Nagatsu T, Sawada M.
    J Neurosci Res; 2007 Jun 28; 85(8):1752-61. PubMed ID: 17469135
    [Abstract] [Full Text] [Related]

  • 19. Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors.
    Heikkila RE, Manzino L, Cabbat FS, Duvoisin RC.
    Nature; 2007 Jun 28; 311(5985):467-9. PubMed ID: 6332989
    [Abstract] [Full Text] [Related]

  • 20. Different susceptibility to 1-methyl-4-phenylpyridium (MPP(+))-induced nigro-striatal dopaminergic cell loss between C57BL/6 and BALB/c mice is not related to the difference of monoamine oxidase-B (MAO-B).
    Ito T, Suzuki K, Uchida K, Nakayama H.
    Exp Toxicol Pathol; 2013 Jan 28; 65(1-2):153-8. PubMed ID: 21855308
    [Abstract] [Full Text] [Related]

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