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Journal Abstract Search


381 related items for PubMed ID: 34948292

  • 1. Alterations in Kynurenine and NAD+ Salvage Pathways during the Successful Treatment of Inflammatory Bowel Disease Suggest HCAR3 and NNMT as Potential Drug Targets.
    Wnorowski A, Wnorowska S, Kurzepa J, Parada-Turska J.
    Int J Mol Sci; 2021 Dec 16; 22(24):. PubMed ID: 34948292
    [Abstract] [Full Text] [Related]

  • 2. An Insight into the Roles of Dietary Tryptophan and Its Metabolites in Intestinal Inflammation and Inflammatory Bowel Disease.
    Li X, Zhang ZH, Zabed HM, Yun J, Zhang G, Qi X.
    Mol Nutr Food Res; 2021 Mar 16; 65(5):e2000461. PubMed ID: 33216452
    [Abstract] [Full Text] [Related]

  • 3. Tryptophan-kynurenine metabolism: a link between the gut and brain for depression in inflammatory bowel disease.
    Chen LM, Bao CH, Wu Y, Liang SH, Wang D, Wu LY, Huang Y, Liu HR, Wu HG.
    J Neuroinflammation; 2021 Jun 14; 18(1):135. PubMed ID: 34127024
    [Abstract] [Full Text] [Related]

  • 4. Tryptophan metabolites modulate inflammatory bowel disease and colorectal cancer by affecting immune system.
    Ala M.
    Int Rev Immunol; 2022 Jun 14; 41(3):326-345. PubMed ID: 34289794
    [Abstract] [Full Text] [Related]

  • 5. Increased fatty acid oxidation and mitochondrial proliferation in liver are associated with increased plasma kynurenine metabolites and nicotinamide levels in normolipidemic and carnitine-depleted rats.
    Lindquist C, Bjørndal B, Lund A, Slettom G, Skorve J, Nygård O, Svardal A, Berge RK.
    Biochim Biophys Acta Mol Cell Biol Lipids; 2020 Feb 14; 1865(2):158543. PubMed ID: 31676443
    [Abstract] [Full Text] [Related]

  • 6. Insulin resistance and dysregulation of tryptophan-kynurenine and kynurenine-nicotinamide adenine dinucleotide metabolic pathways.
    Oxenkrug G.
    Mol Neurobiol; 2013 Oct 14; 48(2):294-301. PubMed ID: 23813101
    [Abstract] [Full Text] [Related]

  • 7. A novel causative role of imbalanced kynurenine pathway in ulcerative colitis: Upregulation of KMO and KYNU promotes intestinal inflammation.
    Shi Y, Luo S, Zhai J, Chen Y.
    Biochim Biophys Acta Mol Basis Dis; 2024 Feb 14; 1870(2):166929. PubMed ID: 37918679
    [Abstract] [Full Text] [Related]

  • 8. Tryptophan metabolism and disposition in cancer biology and immunotherapy.
    Badawy AA.
    Biosci Rep; 2022 Nov 30; 42(11):. PubMed ID: 36286592
    [Abstract] [Full Text] [Related]

  • 9. Increased expression of kynurenine aminotransferases mRNA in lymphocytes of patients with inflammatory bowel disease.
    Dudzińska E, Szymona K, Kloc R, Gil-Kulik P, Kocki T, Świstowska M, Bogucki J, Kocki J, Urbanska EM.
    Therap Adv Gastroenterol; 2019 Nov 30; 12():1756284819881304. PubMed ID: 31666808
    [Abstract] [Full Text] [Related]

  • 10. Kynurenine 3-monooxygenase limits de novo NAD+ synthesis through dietary tryptophan in renal proximal tubule epithelial cell models.
    Zhai Y, Chavez JA, D'Aquino KE, Meng R, Nawrocki AR, Pocai A, Wang L, Ma LJ.
    Am J Physiol Cell Physiol; 2024 May 01; 326(5):C1423-C1436. PubMed ID: 38497113
    [Abstract] [Full Text] [Related]

  • 11. DSS-induced colitis activates the kynurenine pathway in serum and brain by affecting IDO-1 and gut microbiota.
    Zhao LP, Wu J, Quan W, Zhou Y, Hong H, Niu GY, Li T, Huang SB, Qiao CM, Zhao WJ, Cui C, Shen YQ.
    Front Immunol; 2022 May 01; 13():1089200. PubMed ID: 36776388
    [Abstract] [Full Text] [Related]

  • 12. L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences.
    Fujigaki H, Yamamoto Y, Saito K.
    Neuropharmacology; 2017 Jan 01; 112(Pt B):264-274. PubMed ID: 26767951
    [Abstract] [Full Text] [Related]

  • 13. Quinolinate as a Marker for Kynurenine Metabolite Formation and the Unresolved Question of NAD+ Synthesis During Inflammation and Infection.
    Moffett JR, Arun P, Puthillathu N, Vengilote R, Ives JA, Badawy AA, Namboodiri AM.
    Front Immunol; 2020 Jan 01; 11():31. PubMed ID: 32153556
    [Abstract] [Full Text] [Related]

  • 14. A Minimal Kynurenine Pathway Was Preserved for Rhodoquinone but Not for De Novo NAD+ Biosynthesis in Parasitic Worms: The Essential Role of NAD+ Rescue Pathways.
    Comas-Ghierra R, Alshaheeb A, McReynolds MR, Shepherd JN, Salinas G.
    Antioxid Redox Signal; 2024 May 01; 40(13-15):737-750. PubMed ID: 37639366
    [Abstract] [Full Text] [Related]

  • 15. NAD metabolism fuels human and mouse intestinal inflammation.
    Gerner RR, Klepsch V, Macheiner S, Arnhard K, Adolph TE, Grander C, Wieser V, Pfister A, Moser P, Hermann-Kleiter N, Baier G, Oberacher H, Tilg H, Moschen AR.
    Gut; 2018 Oct 01; 67(10):1813-1823. PubMed ID: 28877980
    [Abstract] [Full Text] [Related]

  • 16. A metabolic constraint in the kynurenine pathway drives mucosal inflammation in IBD.
    Welz L, Harris DM, Kim NM, Alsaadi AI, Wu Q, Oumari M, Taubenheim J, Volk V, Credido G, Koncina E, Mukherjee PK, Tran F, Sievers LK, Pavlidis P, Powell N, Rieder F, Letellier E, Waschina S, Kaleta C, Feuerhake F, Verstockt B, McReynolds MR, Rosenstiel P, Schreiber S, Aden K.
    medRxiv; 2024 Aug 08. PubMed ID: 39211892
    [Abstract] [Full Text] [Related]

  • 17. Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice.
    Tashita C, Hoshi M, Hirata A, Nakamoto K, Ando T, Hattori T, Yamamoto Y, Tezuka H, Tomita H, Hara A, Saito K.
    World J Gastroenterol; 2020 Mar 07; 26(9):918-932. PubMed ID: 32206003
    [Abstract] [Full Text] [Related]

  • 18. Hepatic steatosis induced in C57BL/6 mice by a non-ß oxidizable fatty acid analogue is associated with reduced plasma kynurenine metabolites and a modified hepatic NAD+/NADH ratio.
    Berge RK, Cacabelos D, Señarís R, Nordrehaug JE, Nygård O, Skorve J, Bjørndal B.
    Lipids Health Dis; 2020 May 14; 19(1):94. PubMed ID: 32410680
    [Abstract] [Full Text] [Related]

  • 19. Alterations in tryptophan metabolism and de novo NAD+ biosynthesis within the microbiota-gut-brain axis in chronic intestinal inflammation.
    Devereaux J, Robinson AM, Stavely R, Davidson M, Dargahi N, Ephraim R, Kiatos D, Apostolopoulos V, Nurgali K.
    Front Med (Lausanne); 2024 May 14; 11():1379335. PubMed ID: 39015786
    [Abstract] [Full Text] [Related]

  • 20. Activation of the Kynurenine Pathway in Human Malignancies Can Be Suppressed by the Cyclin-Dependent Kinase Inhibitor Dinaciclib.
    Riess C, Schneider B, Kehnscherper H, Gesche J, Irmscher N, Shokraie F, Classen CF, Wirthgen E, Domanska G, Zimpfer A, Strüder D, Junghanss C, Maletzki C.
    Front Immunol; 2020 May 14; 11():55. PubMed ID: 32117235
    [Abstract] [Full Text] [Related]


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