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Journal Abstract Search

248 related items for PubMed ID: 34949826

  • 1. The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota L-carnitine catabolism.
    Buffa JA, Romano KA, Copeland MF, Cody DB, Zhu W, Galvez R, Fu X, Ward K, Ferrell M, Dai HJ, Skye S, Hu P, Li L, Parlov M, McMillan A, Wei X, Nemet I, Koeth RA, Li XS, Wang Z, Sangwan N, Hajjar AM, Dwidar M, Weeks TL, Bergeron N, Krauss RM, Tang WHW, Rey FE, DiDonato JA, Gogonea V, Gerberick GF, Garcia-Garcia JC, Hazen SL.
    Nat Microbiol; 2022 Jan; 7(1):73-86. PubMed ID: 34949826
    [Abstract] [Full Text] [Related]

  • 2. l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans.
    Koeth RA, Lam-Galvez BR, Kirsop J, Wang Z, Levison BS, Gu X, Copeland MF, Bartlett D, Cody DB, Dai HJ, Culley MK, Li XS, Fu X, Wu Y, Li L, DiDonato JA, Tang WHW, Garcia-Garcia JC, Hazen SL.
    J Clin Invest; 2019 Jan 02; 129(1):373-387. PubMed ID: 30530985
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  • 6. In older women, a high-protein diet including animal-sourced foods did not impact serum levels and urinary excretion of trimethylamine-N-oxide.
    Dahl WJ, Hung WL, Ford AL, Suh JH, Auger J, Nagulesapillai V, Wang Y.
    Nutr Res; 2020 Jun 02; 78():72-81. PubMed ID: 32544852
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  • 8. Assembling the anaerobic gamma-butyrobetaine to TMA metabolic pathway in Escherichia fergusonii and confirming its role in TMA production from dietary L-carnitine in murine models.
    Dwidar M, Buffa JA, Wang Z, Santos A, Tittle AN, Fu X, Hajjar AM, DiDonato JA, Hazen SL.
    mBio; 2023 Oct 31; 14(5):e0093723. PubMed ID: 37737636
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  • 9. Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
    Koeth RA, Wang Z, Levison BS, Buffa JA, Org E, Sheehy BT, Britt EB, Fu X, Wu Y, Li L, Smith JD, DiDonato JA, Chen J, Li H, Wu GD, Lewis JD, Warrier M, Brown JM, Krauss RM, Tang WH, Bushman FD, Lusis AJ, Hazen SL.
    Nat Med; 2013 May 31; 19(5):576-85. PubMed ID: 23563705
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  • 10. Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women.
    Wang Z, Bergeron N, Levison BS, Li XS, Chiu S, Jia X, Koeth RA, Li L, Wu Y, Tang WHW, Krauss RM, Hazen SL.
    Eur Heart J; 2019 Feb 14; 40(7):583-594. PubMed ID: 30535398
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  • 11. The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis.
    Skagen K, Trøseid M, Ueland T, Holm S, Abbas A, Gregersen I, Kummen M, Bjerkeli V, Reier-Nilsen F, Russell D, Svardal A, Karlsen TH, Aukrust P, Berge RK, Hov JE, Halvorsen B, Skjelland M.
    Atherosclerosis; 2016 Apr 14; 247():64-9. PubMed ID: 26868510
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  • 12. Identification of TMAO-producer phenotype and host-diet-gut dysbiosis by carnitine challenge test in human and germ-free mice.
    Wu WK, Chen CC, Liu PY, Panyod S, Liao BY, Chen PC, Kao HL, Kuo HC, Kuo CH, Chiu THT, Chen RA, Chuang HL, Huang YT, Zou HB, Hsu CC, Chang TY, Lin CL, Ho CT, Yu HT, Sheen LY, Wu MS.
    Gut; 2019 Aug 14; 68(8):1439-1449. PubMed ID: 30377191
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  • 13. Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk.
    Li XS, Wang Z, Cajka T, Buffa JA, Nemet I, Hurd AG, Gu X, Skye SM, Roberts AB, Wu Y, Li L, Shahen CJ, Wagner MA, Hartiala JA, Kerby RL, Romano KA, Han Y, Obeid S, Lüscher TF, Allayee H, Rey FE, DiDonato JA, Fiehn O, Tang WHW, Hazen SL.
    JCI Insight; 2018 Mar 22; 3(6):. PubMed ID: 29563342
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  • 14. Flavin monooxygenase 3, the host hepatic enzyme in the metaorganismal trimethylamine N-oxide-generating pathway, modulates platelet responsiveness and thrombosis risk.
    Zhu W, Buffa JA, Wang Z, Warrier M, Schugar R, Shih DM, Gupta N, Gregory JC, Org E, Fu X, Li L, DiDonato JA, Lusis AJ, Brown JM, Hazen SL.
    J Thromb Haemost; 2018 Sep 22; 16(9):1857-1872. PubMed ID: 29981269
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  • 15. Characterization of TMAO productivity from carnitine challenge facilitates personalized nutrition and microbiome signatures discovery.
    Wu WK, Panyod S, Liu PY, Chen CC, Kao HL, Chuang HL, Chen YH, Zou HB, Kuo HC, Kuo CH, Liao BY, Chiu THT, Chung CH, Lin AY, Lee YC, Tang SL, Wang JT, Wu YW, Hsu CC, Sheen LY, Orekhov AN, Wu MS.
    Microbiome; 2020 Nov 19; 8(1):162. PubMed ID: 33213511
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  • 16. Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation.
    Kuka J, Liepinsh E, Makrecka-Kuka M, Liepins J, Cirule H, Gustina D, Loza E, Zharkova-Malkova O, Grinberga S, Pugovics O, Dambrova M.
    Life Sci; 2014 Nov 11; 117(2):84-92. PubMed ID: 25301199
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  • 17. The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection.
    Trøseid M, Mayerhofer CCK, Broch K, Arora S, Svardal A, Hov JR, Andreassen AK, Gude E, Karason K, Dellgren G, Berge RK, Gullestad L, Aukrust P, Ueland T.
    J Heart Lung Transplant; 2019 Oct 11; 38(10):1097-1103. PubMed ID: 31301965
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  • 18. The use of an in-vitro batch fermentation (human colon) model for investigating mechanisms of TMA production from choline, L-carnitine and related precursors by the human gut microbiota.
    Day-Walsh P, Shehata E, Saha S, Savva GM, Nemeckova B, Speranza J, Kellingray L, Narbad A, Kroon PA.
    Eur J Nutr; 2021 Oct 11; 60(7):3987-3999. PubMed ID: 33934200
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  • 19. Intestinal microbiota composition modulates choline bioavailability from diet and accumulation of the proatherogenic metabolite trimethylamine-N-oxide.
    Romano KA, Vivas EI, Amador-Noguez D, Rey FE.
    mBio; 2015 Mar 17; 6(2):e02481. PubMed ID: 25784704
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