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Journal Abstract Search

256 related items for PubMed ID: 3495000

  • 1. Correlation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity with blood-brain barrier monoamine oxidase activity.
    Kalaria RN, Mitchell MJ, Harik SI.
    Proc Natl Acad Sci U S A; 1987 May; 84(10):3521-5. PubMed ID: 3495000
    [Abstract] [Full Text] [Related]

  • 2. Strain differences in systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in mice correlate best with monoamine oxidase activity at the blood-brain barrier.
    Riachi NJ, Harik SI.
    Life Sci; 1988 May; 42(23):2359-63. PubMed ID: 3259663
    [Abstract] [Full Text] [Related]

  • 3. On the mechanisms underlying 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. II. Susceptibility among mammalian species correlates with the toxin's metabolic patterns in brain microvessels and liver.
    Riachi NJ, Harik SI, Kalaria RN, Sayre LM.
    J Pharmacol Exp Ther; 1988 Feb; 244(2):443-8. PubMed ID: 3258032
    [Abstract] [Full Text] [Related]

  • 4. Blood-brain barrier monoamine oxidase: enzyme characterization in cerebral microvessels and other tissues from six mammalian species, including human.
    Kalaria RN, Harik SI.
    J Neurochem; 1987 Sep; 49(3):856-64. PubMed ID: 2886556
    [Abstract] [Full Text] [Related]

  • 5. Similar distribution of monoamine oxidase (MAO) and parkinsonian toxin (MPTP) binding sites in human brain.
    Reznikoff G, Manaker S, Parsons B, Rhodes CH, Rainbow TC.
    Neurology; 1985 Oct; 35(10):1415-9. PubMed ID: 3875804
    [Abstract] [Full Text] [Related]

  • 6. Localization in rat brain of binding sites for parkinsonian toxin MPTP: similarities with [3H]pargyline binding to monoamine oxidase.
    Rainbow TC, Parsons B, Wieczorek CM, Manaker S.
    Brain Res; 1985 Mar 25; 330(2):337-42. PubMed ID: 3872699
    [Abstract] [Full Text] [Related]

  • 7. Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains.
    Riachi NJ, Behmand RA, Harik SI.
    Brain Res; 1991 Jul 26; 555(1):19-24. PubMed ID: 1933326
    [Abstract] [Full Text] [Related]

  • 8. Prevention of MPTP-induced neurotoxicity by AGN-1133 and AGN-1135, selective inhibitors of monoamine oxidase-B.
    Heikkila RE, Duvoisin RC, Finberg JP, Youdim MB.
    Eur J Pharmacol; 1985 Oct 22; 116(3):313-7. PubMed ID: 3935467
    [Abstract] [Full Text] [Related]

  • 9. Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase.
    Chiba K, Trevor A, Castagnoli N.
    Biochem Biophys Res Commun; 1984 Apr 30; 120(2):574-8. PubMed ID: 6428396
    [Abstract] [Full Text] [Related]

  • 10. Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. I. Evaluation of the biological activity of MPTP analogs.
    Youngster SK, Sonsalla PK, Sieber BA, Heikkila RE.
    J Pharmacol Exp Ther; 1989 Jun 30; 249(3):820-8. PubMed ID: 2786564
    [Abstract] [Full Text] [Related]

  • 11. Metabolism of the neurotoxin in MPTP by human liver monoamine oxidase B.
    Fritz RR, Abell CW, Patel NT, Gessner W, Brossi A.
    FEBS Lett; 1985 Jul 08; 186(2):224-8. PubMed ID: 3874094
    [Abstract] [Full Text] [Related]

  • 12. A reactive metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is formed in rat brain in vitro by type B monoamine oxidase.
    Corsini GU, Pintus S, Bocchetta A, Piccardi MP, Del Zompo M.
    J Pharmacol Exp Ther; 1986 Aug 08; 238(2):648-52. PubMed ID: 3488394
    [Abstract] [Full Text] [Related]

  • 13. Potent neurotoxic fluorinated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs as potential probes in models of Parkinson disease.
    Riachi NJ, Arora PK, Sayre LM, Harik SI.
    J Neurochem; 1988 Apr 08; 50(4):1319-21. PubMed ID: 3258018
    [Abstract] [Full Text] [Related]

  • 14. Studies on the mechanism of action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Cohen G, Mytilineou C.
    Life Sci; 1985 Jan 21; 36(3):237-42. PubMed ID: 3917526
    [Abstract] [Full Text] [Related]

  • 15. Pargyline prevents MPTP-induced parkinsonism in primates.
    Langston JW, Irwin I, Langston EB, Forno LS.
    Science; 1984 Sep 28; 225(4669):1480-2. PubMed ID: 6332378
    [Abstract] [Full Text] [Related]

  • 16. Oxidation of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by monoamine oxidases A and B and suicide inactivation of the enzymes by MPTP.
    Salach JI, Singer TP, Castagnoli N, Trevor A.
    Biochem Biophys Res Commun; 1984 Dec 14; 125(2):831-5. PubMed ID: 6335034
    [Abstract] [Full Text] [Related]

  • 17. Effects of internal carotid administration of MPTP on rat brain and blood-brain barrier.
    Riachi NJ, Dietrich WD, Harik SI.
    Brain Res; 1990 Nov 12; 533(1):6-14. PubMed ID: 2085733
    [Abstract] [Full Text] [Related]

  • 18. Monoamine oxidases of the human brain and liver.
    Kalaria RN, Mitchell MJ, Harik SI.
    Brain; 1988 Dec 12; 111 ( Pt 6)():1441-51. PubMed ID: 3208065
    [Abstract] [Full Text] [Related]

  • 19. Involvement of monoamine oxidase enzymes in the action of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine, a selective neurotoxin, in the squirrel monkey: binding and biochemical studies.
    Del Zompo M, Piccardi MP, Bernardi F, Bonuccelli U, Corsini GU.
    Brain Res; 1986 Jul 23; 378(2):320-4. PubMed ID: 3089539
    [Abstract] [Full Text] [Related]

  • 20. Histochemistry of MPTP oxidation in the rat brain: sites of synthesis of the parkinsonism-inducing toxin MPP+.
    Nakamura S, Vincent SR.
    Neurosci Lett; 1986 Apr 24; 65(3):321-5. PubMed ID: 3487052
    [Abstract] [Full Text] [Related]

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