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250 related items for PubMed ID: 3495754

  • 1. Astrocytes convert the parkinsonism inducing neurotoxin, MPTP, to its active metabolite, MPP+.
    Ransom BR, Kunis DM, Irwin I, Langston JW.
    Neurosci Lett; 1987 Apr 10; 75(3):323-8. PubMed ID: 3495754
    [Abstract] [Full Text] [Related]

  • 2. Pargyline prevents MPTP-induced parkinsonism in primates.
    Langston JW, Irwin I, Langston EB, Forno LS.
    Science; 1984 Sep 28; 225(4669):1480-2. PubMed ID: 6332378
    [Abstract] [Full Text] [Related]

  • 3. Role of 1-methyl-4-phenylpyridinium ion formation and accumulation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity to isolated hepatocytes.
    Di Monte D, Ekström G, Shinka T, Smith MT, Trevor AJ, Castagnoli N.
    Chem Biol Interact; 1987 Sep 28; 62(2):105-16. PubMed ID: 3496169
    [Abstract] [Full Text] [Related]

  • 4. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolism and 1-methyl-4-phenylpyridinium uptake in dissociated cell cultures from the embryonic mesencephalon.
    Schinelli S, Zuddas A, Kopin IJ, Barker JL, di Porzio U.
    J Neurochem; 1988 Jun 28; 50(6):1900-7. PubMed ID: 3259619
    [Abstract] [Full Text] [Related]

  • 5. Production and disposition of 1-methyl-4-phenylpyridinium in primary cultures of mouse astrocytes.
    Di Monte DA, Wu EY, Irwin I, Delanney LE, Langston JW.
    Glia; 1992 Jun 28; 5(1):48-55. PubMed ID: 1311704
    [Abstract] [Full Text] [Related]

  • 6. Selective accumulation of MPP+ in the substantia nigra: a key to neurotoxicity?
    Irwin I, Langston JW.
    Life Sci; 1985 Jan 21; 36(3):207-12. PubMed ID: 3871240
    [Abstract] [Full Text] [Related]

  • 7. Astrocytes as a primary locus for the conversion MPTP into MPP+.
    Brooks WJ, Jarvis MF, Wagner GC.
    J Neural Transm; 1989 Jan 21; 76(1):1-12. PubMed ID: 2785159
    [Abstract] [Full Text] [Related]

  • 8. Preferential Extracellular Generation of the Active Parkinsonian Toxin MPP+ by Transporter-Independent Export of the Intermediate MPDP+.
    Schildknecht S, Pape R, Meiser J, Karreman C, Strittmatter T, Odermatt M, Cirri E, Friemel A, Ringwald M, Pasquarelli N, Ferger B, Brunner T, Marx A, Möller HM, Hiller K, Leist M.
    Antioxid Redox Signal; 2015 Nov 01; 23(13):1001-16. PubMed ID: 26413876
    [Abstract] [Full Text] [Related]

  • 9. Effects of the parkinsonism-inducing neurotoxin MPTP and its metabolite MPP+ on sympathetic adrenergic nerves in mouse iris and atrium.
    Luthman J, Jonsson G.
    Med Biol; 1986 Nov 01; 64(2-3):95-102. PubMed ID: 3489145
    [Abstract] [Full Text] [Related]

  • 10. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridine (MPP+) cause rapid ATP depletion in isolated hepatocytes.
    Di Monte D, Jewell SA, Ekström G, Sandy MS, Smith MT.
    Biochem Biophys Res Commun; 1986 May 29; 137(1):310-5. PubMed ID: 3487319
    [Abstract] [Full Text] [Related]

  • 11. Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes.
    Chiba K, Trevor AJ, Castagnoli N.
    Biochem Biophys Res Commun; 1985 May 16; 128(3):1228-32. PubMed ID: 3873939
    [Abstract] [Full Text] [Related]

  • 12. 1-Methyl-4-phenylpyridinium ion (MPP+): identification of a metabolite of MPTP, a toxin selective to the substantia nigra.
    Langston JW, Irwin I, Langston EB, Forno LS.
    Neurosci Lett; 1984 Jul 13; 48(1):87-92. PubMed ID: 6332288
    [Abstract] [Full Text] [Related]

  • 13. Toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in primary cultures of mouse astrocytes.
    Di Monte DA, Wu EY, Delanney LE, Irwin I, Langston JW.
    J Pharmacol Exp Ther; 1992 Apr 13; 261(1):44-9. PubMed ID: 1560384
    [Abstract] [Full Text] [Related]

  • 14. On the mechanisms underlying 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. II. Susceptibility among mammalian species correlates with the toxin's metabolic patterns in brain microvessels and liver.
    Riachi NJ, Harik SI, Kalaria RN, Sayre LM.
    J Pharmacol Exp Ther; 1988 Feb 13; 244(2):443-8. PubMed ID: 3258032
    [Abstract] [Full Text] [Related]

  • 15. Histochemistry of MPTP oxidation in the rat brain: sites of synthesis of the parkinsonism-inducing toxin MPP+.
    Nakamura S, Vincent SR.
    Neurosci Lett; 1986 Apr 24; 65(3):321-5. PubMed ID: 3487052
    [Abstract] [Full Text] [Related]

  • 16. Metabolism of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in a rat pheochromocytoma cell line, PC12h.
    Naoi M, Takahashi T, Nagatsu T.
    Life Sci; 1987 Dec 14; 41(24):2655-61. PubMed ID: 3121966
    [Abstract] [Full Text] [Related]

  • 17. Serotonergic conversion of MPTP and dopaminergic accumulation of MPP+.
    Shen RS, Abell CW, Gessner W, Brossi A.
    FEBS Lett; 1985 Sep 23; 189(2):225-30. PubMed ID: 3876242
    [Abstract] [Full Text] [Related]

  • 18. Biotransformation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in primary cultures of mouse astrocytes.
    Di Monte DA, Wu EY, Irwin I, Delanney LE, Langston JW.
    J Pharmacol Exp Ther; 1991 Aug 23; 258(2):594-600. PubMed ID: 1907660
    [Abstract] [Full Text] [Related]

  • 19. Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium.
    Vyas I, Heikkila RE, Nicklas WJ.
    J Neurochem; 1986 May 23; 46(5):1501-7. PubMed ID: 3485701
    [Abstract] [Full Text] [Related]

  • 20. Accumulation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in cultured cerebellar astrocytes.
    Marini AM, Lipsky RH, Schwartz JP, Kopin IJ.
    J Neurochem; 1992 Apr 23; 58(4):1250-8. PubMed ID: 1548462
    [Abstract] [Full Text] [Related]

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