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Journal Abstract Search

167 related items for PubMed ID: 34959647

  • 21. SARS-CoV-2 Uses Nonstructural Protein 16 To Evade Restriction by IFIT1 and IFIT3.
    Schindewolf C, Lokugamage K, Vu MN, Johnson BA, Scharton D, Plante JA, Kalveram B, Crocquet-Valdes PA, Sotcheff S, Jaworski E, Alvarado RE, Debbink K, Daugherty MD, Weaver SC, Routh AL, Walker DH, Plante KS, Menachery VD.
    J Virol; 2023 Feb 28; 97(2):e0153222. PubMed ID: 36722972
    [Abstract] [Full Text] [Related]

  • 22. Localization of SARS-CoV-2 Capping Enzymes Revealed by an Antibody against the nsp10 Subunit.
    Horova V, Landova B, Hodek J, Chalupsky K, Krafcikova P, Chalupska D, Duchoslav V, Weber J, Boura E, Klima M.
    Viruses; 2021 Jul 29; 13(8):. PubMed ID: 34452352
    [Abstract] [Full Text] [Related]

  • 23. Virtual screening, ADME/T, and binding free energy analysis of anti-viral, anti-protease, and anti-infectious compounds against NSP10/NSP16 methyltransferase and main protease of SARS CoV-2.
    Maurya SK, Maurya AK, Mishra N, Siddique HR.
    J Recept Signal Transduct Res; 2020 Dec 29; 40(6):605-612. PubMed ID: 32476594
    [Abstract] [Full Text] [Related]

  • 24. The Structure-Based Design of SARS-CoV-2 nsp14 Methyltransferase Ligands Yields Nanomolar Inhibitors.
    Otava T, Šála M, Li F, Fanfrlík J, Devkota K, Perveen S, Chau I, Pakarian P, Hobza P, Vedadi M, Boura E, Nencka R.
    ACS Infect Dis; 2021 Aug 13; 7(8):2214-2220. PubMed ID: 34152728
    [Abstract] [Full Text] [Related]

  • 25. A High-Throughput Radioactivity-Based Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex.
    Khalili Yazdi A, Li F, Devkota K, Perveen S, Ghiabi P, Hajian T, Bolotokova A, Vedadi M.
    SLAS Discov; 2021 Jul 13; 26(6):757-765. PubMed ID: 33874769
    [Abstract] [Full Text] [Related]

  • 26. In silico evaluation of S-adenosyl-L-homocysteine analogs as inhibitors of nsp14-viral cap N7 methyltranferase and PLpro of SARS-CoV-2: synthesis, molecular docking, physicochemical data, ADMET and molecular dynamics simulations studies.
    Srivastava R, Panda SK, Sen Gupta PS, Chaudhary A, Naaz F, Yadav AK, Ram NK, Rana MK, Singh RK, Srivastava R.
    J Biomol Struct Dyn; 2023 Dec 26; ():1-18. PubMed ID: 38147408
    [Abstract] [Full Text] [Related]

  • 27. In silico identification of novel SARS-COV-2 2'-O-methyltransferase (nsp16) inhibitors: structure-based virtual screening, molecular dynamics simulation and MM-PBSA approaches.
    El Hassab MA, Ibrahim TM, Al-Rashood ST, Alharbi A, Eskandrani RO, Eldehna WM.
    J Enzyme Inhib Med Chem; 2021 Dec 26; 36(1):727-736. PubMed ID: 33685335
    [Abstract] [Full Text] [Related]

  • 28. Synthetic Platforms for Characterizing and Targeting of SARS-CoV-2 Genome Capping Enzymes.
    Ornelas MY, Thomas AY, Johnson Rosas LI, Scoville RO, Mehta AP.
    ACS Synth Biol; 2022 Nov 18; 11(11):3759-3771. PubMed ID: 36331143
    [Abstract] [Full Text] [Related]

  • 29. Yeast-based assays for the high-throughput screening of inhibitors of coronavirus RNA cap guanine-N7-methyltransferase.
    Sun Y, Wang Z, Tao J, Wang Y, Wu A, Yang Z, Wang K, Shi L, Chen Y, Guo D.
    Antiviral Res; 2014 Apr 18; 104():156-64. PubMed ID: 24530452
    [Abstract] [Full Text] [Related]

  • 30. Crystal structures and fragment screening of SARS-CoV-2 NSP14 reveal details of exoribonuclease activation and mRNA capping and provide starting points for antiviral drug development.
    Imprachim N, Yosaatmadja Y, Newman JA.
    Nucleic Acids Res; 2023 Jan 11; 51(1):475-487. PubMed ID: 36546776
    [Abstract] [Full Text] [Related]

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  • 33. Coronavirus Inhibitors Targeting nsp16.
    Omer EA, Abdelfatah S, Riedl M, Meesters C, Hildebrandt A, Efferth T.
    Molecules; 2023 Jan 18; 28(3):. PubMed ID: 36770656
    [Abstract] [Full Text] [Related]

  • 34. Structural Basis for Inhibition of the SARS-CoV-2 nsp16 by Substrate-Based Dual Site Inhibitors.
    Kalnins G, Rudusa L, Bula AL, Zelencova-Gopejenko D, Bobileva O, Sisovs M, Tars K, Jirgensons A, Jaudzems K, Bobrovs R.
    ChemMedChem; 2024 Dec 16; 19(24):e202400618. PubMed ID: 39258386
    [Abstract] [Full Text] [Related]

  • 35. N-Arylsulfonamide-based adenosine analogues to target RNA cap N7-methyltransferase nsp14 of SARS-CoV-2.
    Ahmed-Belkacem R, Troussier J, Delpal A, Canard B, Vasseur JJ, Decroly E, Debart F.
    RSC Med Chem; 2024 Mar 20; 15(3):839-847. PubMed ID: 38516599
    [Abstract] [Full Text] [Related]

  • 36. Structure-Based Discovery of Inhibitors of the SARS-CoV-2 Nsp14 N7-Methyltransferase.
    Singh I, Li F, Fink EA, Chau I, Li A, Rodriguez-Hernández A, Glenn I, Zapatero-Belinchón FJ, Rodriguez ML, Devkota K, Deng Z, White K, Wan X, Tolmachova NA, Moroz YS, Kaniskan HÜ, Ott M, García-Sastre A, Jin J, Fujimori DG, Irwin JJ, Vedadi M, Shoichet BK.
    J Med Chem; 2023 Jun 22; 66(12):7785-7803. PubMed ID: 37294077
    [Abstract] [Full Text] [Related]

  • 37. Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP.
    Jin X, Chen Y, Sun Y, Zeng C, Wang Y, Tao J, Wu A, Yu X, Zhang Z, Tian J, Guo D.
    Virus Res; 2013 Sep 22; 176(1-2):45-52. PubMed ID: 23702198
    [Abstract] [Full Text] [Related]

  • 38. Structure-based and ligand-based virtual screening of novel methyltransferase inhibitors of the dengue virus.
    Lim SV, Rahman MB, Tejo BA.
    BMC Bioinformatics; 2011 Sep 22; 12 Suppl 13(Suppl 13):S24. PubMed ID: 22373153
    [Abstract] [Full Text] [Related]

  • 39. Reconstitution of RNA cap methylation reveals different features of SARS-CoV-2 and SARS-CoV methyltransferases.
    He M, Cao L, Liu L, Jin X, Zheng B, Liu X, Zhuang J, Zhang F, Yang Z, Ji Y, Xu T, Huang S, Chen J, Xie L, Li K, Hou P, Pan J, Guo D, Li C.
    J Med Virol; 2024 Feb 22; 96(2):e29411. PubMed ID: 38285434
    [Abstract] [Full Text] [Related]

  • 40. Identification and Inhibition of the Druggable Allosteric Site of SARS-CoV-2 NSP10/NSP16 Methyltransferase through Computational Approaches.
    Faisal S, Badshah SL, Kubra B, Sharaf M, Emwas AH, Jaremko M, Abdalla M.
    Molecules; 2022 Aug 17; 27(16):. PubMed ID: 36014480
    [Abstract] [Full Text] [Related]

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