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Journal Abstract Search

145 related items for PubMed ID: 34966720

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  • 3. Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization.
    Champiré A, Berabez R, Braka A, Cosson A, Corret J, Girardin C, Serrano A, Aci-Sèche S, Bonnet P, Josselin B, Brindeau P, Ruchaud S, Leguevel R, Chatterjee D, Mathea S, Knapp S, Brion R, Verrecchia F, Vallée B, Plé K, Bénédetti H, Routier S.
    Eur J Med Chem; 2024 May 05; 271():116391. PubMed ID: 38669909
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  • 4. LIM Kinases, LIMK1 and LIMK2, Are Crucial Node Actors of the Cell Fate: Molecular to Pathological Features.
    Villalonga E, Mosrin C, Normand T, Girardin C, Serrano A, Žunar B, Doudeau M, Godin F, Bénédetti H, Vallée B.
    Cells; 2023 Mar 04; 12(5):. PubMed ID: 36899941
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  • 5. Discovery of bis-aryl urea derivatives as potent and selective Limk inhibitors: Exploring Limk1 activity and Limk1/ROCK2 selectivity through a combined computational study.
    Cui J, Ding M, Deng W, Yin Y, Wang Z, Zhou H, Sun G, Jiang Y, Feng Y.
    Bioorg Med Chem; 2015 Dec 01; 23(23):7464-77. PubMed ID: 26545798
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  • 6. Comparative Analysis of Small-Molecule LIMK1/2 Inhibitors: Chemical Synthesis, Biochemistry, and Cellular Activity.
    Collins R, Lee H, Jones DH, Elkins JM, Gillespie JA, Thomas C, Baldwin AG, Jones K, Waters L, Paine M, Atack JR, Ward SE, Grubisha O, Foley DW.
    J Med Chem; 2022 Oct 27; 65(20):13705-13713. PubMed ID: 36205722
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  • 7. Impaired spermatogenic ability of testicular germ cells in mice deficient in the LIM-kinase 2 gene.
    Takahashi H, Koshimizu U, Miyazaki J, Nakamura T.
    Dev Biol; 2002 Jan 15; 241(2):259-72. PubMed ID: 11784110
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  • 8. LIMK2-1, a new isoform of human LIMK2, regulates actin cytoskeleton remodeling via a different signaling pathway than that of its two homologs, LIMK2a and LIMK2b.
    Vallée B, Cuberos H, Doudeau M, Godin F, Gosset D, Vourc'h P, Andres CR, Bénédetti H.
    Biochem J; 2018 Dec 06; 475(23):3745-3761. PubMed ID: 30373762
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  • 9. LIM-kinase as a regulator of actin dynamics in spermatogenesis.
    Takahashi H, Funakoshi H, Nakamura T.
    Cytogenet Genome Res; 2003 Dec 06; 103(3-4):290-8. PubMed ID: 15051950
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  • 10. LIM kinase 1 modulates opsonized zymosan-triggered activation of macrophage-like U937 cells. Possible involvement of phosphorylation of cofilin and reorganization of actin cytoskeleton.
    Matsui S, Matsumoto S, Adachi R, Kusui K, Hirayama A, Watanabe H, Ohashi K, Mizuno K, Yamaguchi T, Kasahara T, Suzuki K.
    J Biol Chem; 2002 Jan 04; 277(1):544-9. PubMed ID: 11694543
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  • 11. Lim kinases, regulators of actin dynamics.
    Bernard O.
    Int J Biochem Cell Biol; 2007 Jan 04; 39(6):1071-6. PubMed ID: 17188549
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  • 12. Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase.
    Sumi T, Matsumoto K, Nakamura T.
    J Biol Chem; 2001 Jan 05; 276(1):670-6. PubMed ID: 11018042
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  • 13. LIMK1 and LIMK2 are important for metastatic behavior and tumor cell-induced angiogenesis of pancreatic cancer cells.
    Vlecken DH, Bagowski CP.
    Zebrafish; 2009 Dec 05; 6(4):433-9. PubMed ID: 20047470
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  • 14. Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeleton.
    Mashiach-Farkash E, Rak R, Elad-Sfadia G, Haklai R, Carmeli S, Kloog Y, Wolfson HJ.
    Oncotarget; 2012 Jun 05; 3(6):629-39. PubMed ID: 22776759
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  • 15. Novel LIMK2 Inhibitor Blocks Panc-1 Tumor Growth in a mouse xenograft model.
    Rak R, Haklai R, Elad-Tzfadia G, Wolfson HJ, Carmeli S, Kloog Y.
    Oncoscience; 2014 Jun 05; 1(1):39-48. PubMed ID: 25593987
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  • 16. LIMK/cofilin pathway and Slingshot are implicated in human colorectal cancer progression and chemoresistance.
    Aggelou H, Chadla P, Nikou S, Karteri S, Maroulis I, Kalofonos HP, Papadaki H, Bravou V.
    Virchows Arch; 2018 May 05; 472(5):727-737. PubMed ID: 29352327
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  • 17. LIM kinase and slingshot are critical for neurite extension.
    Endo M, Ohashi K, Mizuno K.
    J Biol Chem; 2007 May 04; 282(18):13692-702. PubMed ID: 17360713
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  • 18. LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation.
    Mardilovich K, Baugh M, Crighton D, Kowalczyk D, Gabrielsen M, Munro J, Croft DR, Lourenco F, James D, Kalna G, McGarry L, Rath O, Shanks E, Garnett MJ, McDermott U, Brookfield J, Charles M, Hammonds T, Olson MF.
    Oncotarget; 2015 Nov 17; 6(36):38469-86. PubMed ID: 26540348
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  • 19. LIM kinase inhibition reduces breast cancer growth and invasiveness but systemic inhibition does not reduce metastasis in mice.
    Li R, Doherty J, Antonipillai J, Chen S, Devlin M, Visser K, Baell J, Street I, Anderson RL, Bernard O.
    Clin Exp Metastasis; 2013 Apr 17; 30(4):483-95. PubMed ID: 23239465
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  • 20. Design, synthesis and biological characterization of selective LIMK inhibitors.
    Boland S, Bourin A, Alen J, Geraets J, Schroeders P, Castermans K, Kindt N, Boumans N, Panitti L, Vanormelingen J, Fransen S, Van de Velde S, Defert O.
    Bioorg Med Chem Lett; 2015 Sep 15; 25(18):4005-10. PubMed ID: 26233434
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