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Journal Abstract Search

208 related items for PubMed ID: 34968902

  • 1. Synthesis and biological evaluation of celastrol derivatives as potential anti-glioma agents by activating RIP1/RIP3/MLKL pathway to induce necroptosis.
    Feng Y, Wang W, Zhang Y, Fu X, Ping K, Zhao J, Lei Y, Mou Y, Wang S.
    Eur J Med Chem; 2022 Feb 05; 229():114070. PubMed ID: 34968902
    [Abstract] [Full Text] [Related]

  • 2. Emodin induced necroptosis in the glioma cell line U251 via the TNF-α/RIP1/RIP3 pathway.
    Zhou J, Li G, Han G, Feng S, Liu Y, Chen J, Liu C, Zhao L, Jin F.
    Invest New Drugs; 2020 Feb 05; 38(1):50-59. PubMed ID: 30924024
    [Abstract] [Full Text] [Related]

  • 3. Shikonin induces glioma cell necroptosis in vitro by ROS overproduction and promoting RIP1/RIP3 necrosome formation.
    Lu B, Gong X, Wang ZQ, Ding Y, Wang C, Luo TF, Piao MH, Meng FK, Chi GF, Luo YN, Ge PF.
    Acta Pharmacol Sin; 2017 Nov 05; 38(11):1543-1553. PubMed ID: 28816233
    [Abstract] [Full Text] [Related]

  • 4. RIP1, RIP3, and MLKL Contribute to Cell Death Caused by Clostridium perfringens Enterotoxin.
    Shrestha A, Mehdizadeh Gohari I, McClane BA.
    mBio; 2019 Dec 17; 10(6):. PubMed ID: 31848291
    [Abstract] [Full Text] [Related]

  • 5. Necroptosis regulates tumor repopulation after radiotherapy via RIP1/RIP3/MLKL/JNK/IL8 pathway.
    Wang Y, Zhao M, He S, Luo Y, Zhao Y, Cheng J, Gong Y, Xie J, Wang Y, Hu B, Tian L, Liu X, Li C, Huang Q.
    J Exp Clin Cancer Res; 2019 Nov 09; 38(1):461. PubMed ID: 31706322
    [Abstract] [Full Text] [Related]

  • 6. RIP1 and RIP3 contribute to shikonin-induced DNA double-strand breaks in glioma cells via increase of intracellular reactive oxygen species.
    Zhou Z, Lu B, Wang C, Wang Z, Luo T, Piao M, Meng F, Chi G, Luo Y, Ge P.
    Cancer Lett; 2017 Apr 01; 390():77-90. PubMed ID: 28108311
    [Abstract] [Full Text] [Related]

  • 7. PI3K mediates tumor necrosis factor induced-necroptosis through initiating RIP1-RIP3-MLKL signaling pathway activation.
    Hu S, Chang X, Zhu H, Wang D, Chen G.
    Cytokine; 2020 May 01; 129():155046. PubMed ID: 32114297
    [Abstract] [Full Text] [Related]

  • 8. Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells.
    Sun W, Wu X, Gao H, Yu J, Zhao W, Lu JJ, Wang J, Du G, Chen X.
    Free Radic Biol Med; 2017 Jul 01; 108():433-444. PubMed ID: 28414098
    [Abstract] [Full Text] [Related]

  • 9. Celastrol protects against early brain injury after subarachnoid hemorrhage in rats through alleviating blood-brain barrier disruption and blocking necroptosis.
    Xu H, Cai Y, Yu M, Sun J, Cai J, Li J, Qin B, Ying G, Chen T, Shen Y, Jie L, Xu D, Gu C, Wang C, Hu X, Chen J, Wang L, Chen G.
    Aging (Albany NY); 2021 Jun 28; 13(12):16816-16833. PubMed ID: 34182541
    [Abstract] [Full Text] [Related]

  • 10. ABT‑737, a Bcl‑2 family inhibitor, has a synergistic effect with apoptosis by inducing urothelial carcinoma cell necroptosis.
    Cheng R, Liu X, Wang Z, Tang K.
    Mol Med Rep; 2021 Jun 28; 23(6):. PubMed ID: 33786632
    [Abstract] [Full Text] [Related]

  • 11. Resveratrol inhibits necroptosis by mediating the TNF-α/RIP1/RIP3/MLKL pathway in myocardial hypoxia/reoxygenation injury.
    Hu Y, Pan H, Peng J, He J, Tang M, Yan S, Rong J, Li J, Zheng Z, Wang H, Liu Y, Zhong X.
    Acta Biochim Biophys Sin (Shanghai); 2021 Mar 26; 53(4):430-437. PubMed ID: 33686403
    [Abstract] [Full Text] [Related]

  • 12. Effects of Hsp90 inhibitor on the RIP1-RIP3-MLKL pathway during the development of heart failure in mice.
    Marunouchi T, Nishiumi C, Iinuma S, Yano E, Tanonaka K.
    Eur J Pharmacol; 2021 May 05; 898():173987. PubMed ID: 33640405
    [Abstract] [Full Text] [Related]

  • 13. Celastrol inhibits necroptosis by attenuating the RIPK1/RIPK3/MLKL pathway and confers protection against acute pancreatitis in mice.
    Liang QQ, Shi ZJ, Yuan T, Chen SY, Li YP, Zhang HR, You YP, Xu R, Xu LH, Hu B, Ouyang DY, Zha QB, He XH.
    Int Immunopharmacol; 2023 Apr 05; 117():109974. PubMed ID: 37012867
    [Abstract] [Full Text] [Related]

  • 14. RIP1 and RIP3 contribute to shikonin-induced glycolysis suppression in glioma cells via increase of intracellular hydrogen peroxide.
    Lu B, Wang Z, Ding Y, Wang X, Lu S, Wang C, He C, Piao M, Chi G, Luo Y, Ge P.
    Cancer Lett; 2018 Jul 01; 425():31-42. PubMed ID: 29608987
    [Abstract] [Full Text] [Related]

  • 15. Extracts derived from a traditional Chinese herbal formula triggers necroptosis in ectocervical Ect1/E6E7 cells through activation of RIP1 kinase.
    Chen X, Hu X, Liu L, Liang X, Xiao J.
    J Ethnopharmacol; 2019 Jul 15; 239():111922. PubMed ID: 31034957
    [Abstract] [Full Text] [Related]

  • 16. Non-benzoquinone geldanamycin analogs trigger various forms of death in human breast cancer cells.
    Zhang Z, Li HM, Zhou C, Li Q, Ma L, Zhang Z, Sun Y, Wang L, Zhang X, Zhu B, Hong YS, Wu CZ, Liu H.
    J Exp Clin Cancer Res; 2016 Sep 22; 35(1):149. PubMed ID: 27658586
    [Abstract] [Full Text] [Related]

  • 17. The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis.
    Fu Z, Deng B, Liao Y, Shan L, Yin F, Wang Z, Zeng H, Zuo D, Hua Y, Cai Z.
    BMC Cancer; 2013 Dec 06; 13():580. PubMed ID: 24314238
    [Abstract] [Full Text] [Related]

  • 18. RIP1/RIP3-regulated necroptosis as a target for multifaceted disease therapy (Review).
    Liu Y, Liu T, Lei T, Zhang D, Du S, Girani L, Qi D, Lin C, Tong R, Wang Y.
    Int J Mol Med; 2019 Sep 06; 44(3):771-786. PubMed ID: 31198981
    [Abstract] [Full Text] [Related]

  • 19. The Neuroprotective Effects of Necrostatin-1 on Subarachnoid Hemorrhage in Rats Are Possibly Mediated by Preventing Blood-Brain Barrier Disruption and RIP3-Mediated Necroptosis.
    Chen J, Jin H, Xu H, Peng Y, Jie L, Xu D, Chen L, Li T, Fan L, He P, Ying G, Gu C, Wang C, Wang L, Chen G.
    Cell Transplant; 2019 Nov 06; 28(11):1358-1372. PubMed ID: 31370690
    [Abstract] [Full Text] [Related]

  • 20. Panax notoginseng Saponins Protect Brain Microvascular Endothelial Cells against Oxygen-Glucose Deprivation/Resupply-Induced Necroptosis via Suppression of RIP1-RIP3-MLKL Signaling Pathway.
    Hu Y, Lei H, Zhang S, Ma J, Kang S, Wan L, Li F, Zhang F, Sun T, Zhang C, Li W.
    Neurochem Res; 2022 Nov 06; 47(11):3261-3271. PubMed ID: 35904697
    [Abstract] [Full Text] [Related]

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