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Journal Abstract Search

502 related items for PubMed ID: 34971875

  • 1. Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities.
    Sun YX, Song J, Kong LJ, Sha BB, Tian XY, Liu XJ, Hu T, Chen P, Zhang SY.
    Eur J Med Chem; 2022 Feb 05; 229():114069. PubMed ID: 34971875
    [Abstract] [Full Text] [Related]

  • 2. Discovery of N-benzylarylamide derivatives as novel tubulin polymerization inhibitors capable of activating the Hippo pathway.
    Song J, Wang SH, Song CH, Zhang WX, Zhu JX, Tian XY, Fu XJ, Xu Y, Jin CY, Zhang SY.
    Eur J Med Chem; 2022 Oct 05; 240():114583. PubMed ID: 35834904
    [Abstract] [Full Text] [Related]

  • 3. Discovery of novel N-benzylarylamide-dithiocarbamate based derivatives as dual inhibitors of tubulin polymerization and LSD1 that inhibit gastric cancers.
    Yuan XY, Song CH, Liu XJ, Wang X, Jia MQ, Wang W, Liu WB, Fu XJ, Jin CY, Song J, Zhang SY.
    Eur J Med Chem; 2023 Apr 05; 252():115281. PubMed ID: 36940611
    [Abstract] [Full Text] [Related]

  • 4. Discovery of indoline derivatives as anticancer agents via inhibition of tubulin polymerization.
    Wang SY, Liu X, Meng LW, Li MM, Li YR, Yu GX, Song J, Zhang HY, Chen P, Zhang SY, Hu T.
    Bioorg Med Chem Lett; 2021 Jul 01; 43():128095. PubMed ID: 33965530
    [Abstract] [Full Text] [Related]

  • 5. Discovery of novel coumarin-based derivatives as inhibitors of tubulin polymerization targeting the colchicine binding site with potent anti-gastric cancer activities.
    Tian XY, Zhang WX, Chen XY, Jia MQ, Zhang SY, Chen YF, Yuan S, Song J, Li J.
    Eur J Med Chem; 2024 Feb 05; 265():116079. PubMed ID: 38150962
    [Abstract] [Full Text] [Related]

  • 6. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 05; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 7. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
    Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH.
    J Enzyme Inhib Med Chem; 2021 Dec 05; 36(1):640-658. PubMed ID: 33588683
    [Abstract] [Full Text] [Related]

  • 8. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 9. Discovery of tertiary amide derivatives incorporating benzothiazole moiety as anti-gastric cancer agents in vitro via inhibiting tubulin polymerization and activating the Hippo signaling pathway.
    Song J, Gao QL, Wu BW, Zhu T, Cui XX, Jin CJ, Wang SY, Wang SH, Fu DJ, Liu HM, Zhang SY, Zhang YB, Li YC.
    Eur J Med Chem; 2020 Oct 01; 203():112618. PubMed ID: 32682200
    [Abstract] [Full Text] [Related]

  • 10. A novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo.
    Li YR, Liu FF, Liu WB, Zhang YF, Tian XY, Fu XJ, Xu Y, Song J, Zhang SY.
    Biochem Pharmacol; 2022 Jul 01; 201():115070. PubMed ID: 35526597
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V, Pindiprolu SKSS, Sana S, Ramamurty DSVNM, Madasi JRK, Vadlamani S.
    Anticancer Agents Med Chem; 2021 Jul 01; 21(8):1047-1055. PubMed ID: 32981511
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
    Li G, Wang Y, Li L, Ren Y, Deng X, Liu J, Wang W, Luo M, Liu S, Chen J.
    Eur J Med Chem; 2020 Sep 15; 202():112519. PubMed ID: 32650183
    [Abstract] [Full Text] [Related]

  • 13. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.
    Cui YJ, Ma CC, Zhang CM, Tang LQ, Liu ZP.
    Eur J Med Chem; 2020 Feb 01; 187():111968. PubMed ID: 31865012
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and biological evaluation of novel shikonin-benzo[b]furan derivatives as tubulin polymerization inhibitors targeting the colchicine binding site.
    Shao YY, Yin Y, Lian BP, Leng JF, Xia YZ, Kong LY.
    Eur J Med Chem; 2020 Mar 15; 190():112105. PubMed ID: 32035399
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and biological evaluation of novel acridine and quinoline derivatives as tubulin polymerization inhibitors with anticancer activities.
    Ren Y, Ruan Y, Cheng B, Li L, Liu J, Fang Y, Chen J.
    Bioorg Med Chem; 2021 Sep 15; 46():116376. PubMed ID: 34455231
    [Abstract] [Full Text] [Related]

  • 16. Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance.
    Cheng B, Zhu G, Meng L, Wu G, Chen Q, Ma S.
    Eur J Med Chem; 2022 Jan 15; 228():113930. PubMed ID: 34794817
    [Abstract] [Full Text] [Related]

  • 17. Design and synthesis of novel imidazole-chalcone derivatives as microtubule protein polymerization inhibitors to treat cervical cancer and reverse cisplatin resistance.
    Liu Z, Yang Z, Ablise M.
    Bioorg Chem; 2024 Jun 15; 147():107310. PubMed ID: 38583249
    [Abstract] [Full Text] [Related]

  • 18. Structure-activity relationships and antiproliferative effects of 1,2,3,4-4H-quinoxaline derivatives as tubulin polymerization inhibitors.
    Liang T, Zhou X, Lu L, Dong H, Zhang Y, Xu Y, Qi J, Zhang Y, Wang J.
    Bioorg Chem; 2021 May 15; 110():104793. PubMed ID: 33770673
    [Abstract] [Full Text] [Related]

  • 19. Tubulin inhibitors: Discovery of a new scaffold targeting extra-binding residues within the colchicine site through anchoring substituents properly adapted to their pocket by a semi-flexible linker.
    Maklad RM, AbdelHafez EMN, Abdelhamid D, Aly OM.
    Bioorg Chem; 2020 Jun 15; 99():103767. PubMed ID: 32325332
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and bioevaluation of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazoles as tubulin polymerization inhibitors.
    Liu R, Huang M, Zhang S, Li L, Li M, Sun J, Wu L, Guan Q, Zhang W.
    Eur J Med Chem; 2021 Dec 15; 226():113826. PubMed ID: 34571171
    [Abstract] [Full Text] [Related]

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