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312 related items for PubMed ID: 3498533

  • 1. Enhancement of folate analogue transport inward in L1210 cells during methotrexate therapy of leukemic mice: evidence of the nature of the effect, possible host mediation, and pharmacokinetic significance.
    Sirotnak FM, Poser RE, Barrueco JR.
    Cancer Res; 1987 Oct 15; 47(20):5334-9. PubMed ID: 3498533
    [Abstract] [Full Text] [Related]

  • 2. Further studies on a novel class of genetic variants of the L1210 cell with increased folate analogue transport inward. Transport properties of a new variant, evidence for increased levels of a specific transport protein, and its partial characterization following affinity labeling.
    Yang CH, Sirotnak FM, Mines LS.
    J Biol Chem; 1988 Jul 15; 263(20):9703-9. PubMed ID: 2838477
    [Abstract] [Full Text] [Related]

  • 3. The issues of transport multiplicity and energetics pertaining to methotrexate efflux in L1210 cells addressed by an analysis of cis and trans effects of inhibitors.
    Sirotnak FM, O'Leary DF.
    Cancer Res; 1991 Mar 01; 51(5):1412-7. PubMed ID: 1997179
    [Abstract] [Full Text] [Related]

  • 4. Relative frequency and kinetic properties of transport-defective phenotypes among methotrexate-resistant L1210 clonal cell lines derived in vivo.
    Sirotnak FM, Moccio DM, Kelleher LE, Goutas LJ.
    Cancer Res; 1981 Nov 01; 41(11 Pt 1):4447-52. PubMed ID: 7306968
    [Abstract] [Full Text] [Related]

  • 5. Biochemical and pharmacokinetic effects of leucovorin after high-dose methotrexate in a murine leukemia model.
    Sirotnak FM, Donsbach RC, Moccio DM, Dorick DM.
    Cancer Res; 1976 Dec 01; 36(12):4679-86. PubMed ID: 1087182
    [Abstract] [Full Text] [Related]

  • 6. Characteristics of a novel transport system for folate compounds in wild-type and methotrexate-resistant L1210 cells.
    Henderson GB, Strauss BP.
    Cancer Res; 1990 Mar 15; 50(6):1709-14. PubMed ID: 2306724
    [Abstract] [Full Text] [Related]

  • 7. Extent of the requirement for folate transport by L1210 cells for growth and leukemogenesis in vivo.
    Sirotnak FM, Goutas LJ, Mines LS.
    Cancer Res; 1985 Oct 15; 45(10):4732-4. PubMed ID: 3875399
    [Abstract] [Full Text] [Related]

  • 8. Carrier-mediated transport of folate compounds in L1210 cells. Initial rate kinetics and extent of duality of entry routes for folic acid and diastereomers of 5-methyltetrahydrohomofolate in the presence of physiological anions.
    Sirotnak FM, Goutas LJ, Jacobsen DM, Mines LS, Barrueco JR, Gaumont Y, Kisliuk RL.
    Biochem Pharmacol; 1987 May 15; 36(10):1659-67. PubMed ID: 3593392
    [Abstract] [Full Text] [Related]

  • 9. The mechanism of transport of the multitargeted antifolate (MTA) and its cross-resistance pattern in cells with markedly impaired transport of methotrexate.
    Zhao R, Babani S, Gao F, Liu L, Goldman ID.
    Clin Cancer Res; 2000 Sep 15; 6(9):3687-95. PubMed ID: 10999762
    [Abstract] [Full Text] [Related]

  • 10. Transport of the antitumor antibiotic Cl-920 into L1210 leukemia cells by the reduced folate carrier system.
    Fry DW, Besserer JA, Boritzki TJ.
    Cancer Res; 1984 Aug 15; 44(8):3366-70. PubMed ID: 6547636
    [Abstract] [Full Text] [Related]

  • 11. Relationship of reduced folate changes to inhibition of DNA synthesis induced by methotrexate in L1210 cells in vivo.
    Priest DG, Bunni M, Sirotnak FM.
    Cancer Res; 1989 Aug 01; 49(15):4204-9. PubMed ID: 2743307
    [Abstract] [Full Text] [Related]

  • 12. Functional activity of the reduced folate carrier in KB, MA104, and IGROV-I cells expressing folate-binding protein.
    Westerhof GR, Rijnboutt S, Schornagel JH, Pinedo HM, Peters GJ, Jansen G.
    Cancer Res; 1995 Sep 01; 55(17):3795-802. PubMed ID: 7641196
    [Abstract] [Full Text] [Related]

  • 13. Expression of a folate binding protein in L1210 cells grown in low folate medium.
    Jansen G, Kathmann I, Rademaker BC, Braakhuis BJ, Westerhof GR, Rijksen G, Schornagel JH.
    Cancer Res; 1989 Apr 15; 49(8):1959-63. PubMed ID: 2702638
    [Abstract] [Full Text] [Related]

  • 14. Initial rate kinetics and evidence for duality of mediated transport of adenosine, related purine nucleosides, and nucleoside analogues in L1210 cells.
    Chello PL, Sirotnak FM, Dorick DM, Yang CH, Montgomery JA.
    Cancer Res; 1983 Jan 15; 43(1):97-103. PubMed ID: 6847787
    [Abstract] [Full Text] [Related]

  • 15. Alteration of folate analogue transport inward after induced maturation of HL-60 leukemia cells. Molecular properties of the transporter in an overproducing variant and evidence for down-regulation of its synthesis in maturating cells.
    Yang CH, Pain J, Sirotnak FM.
    J Biol Chem; 1992 Apr 05; 267(10):6628-34. PubMed ID: 1551871
    [Abstract] [Full Text] [Related]

  • 16. Identification of a highly glycosylated methotrexate membrane carrier in K562 human erythroleukemia cells up-regulated for tetrahydrofolate cofactor and methotrexate transport.
    Matherly LH, Czajkowski CA, Angeles SM.
    Cancer Res; 1991 Jul 01; 51(13):3420-6. PubMed ID: 2054782
    [Abstract] [Full Text] [Related]

  • 17. Optimization of high-dose methotrexate with leucovorin rescue therapy in the L1210 leukemia and sarcoma 180 murine tumor models.
    Sirotnak FM, Moccio DM, Dorick DM.
    Cancer Res; 1978 Feb 01; 38(2):345-53. PubMed ID: 304375
    [Abstract] [Full Text] [Related]

  • 18. Improved therapeutic index with high-dose methotrexate: comparison of thymidine-purine rescue with citrovorum factor rescue in mice.
    Samuels LL, Straw JA.
    Cancer Res; 1984 Jun 01; 44(6):2278-84. PubMed ID: 6609764
    [Abstract] [Full Text] [Related]

  • 19. Synthesis of methotrexate polyglutamates in L1210 murine leukemia cells.
    Whitehead VM.
    Cancer Res; 1977 Feb 01; 37(2):408-12. PubMed ID: 832265
    [Abstract] [Full Text] [Related]

  • 20. Biochemical correlates of responsiveness and collateral sensitivity of some methotrexate-resistant murine tumors to the lipophilic antifolate, metoprine.
    Sirotnak FM, Moccio DM, Goutas LJ, Kelleher LE, Montgomery JA.
    Cancer Res; 1982 Mar 01; 42(3):924-8. PubMed ID: 7059991
    [Abstract] [Full Text] [Related]

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