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477 related items for PubMed ID: 35074577

  • 1. VX-11e protects articular cartilage and subchondral bone in osteoarthritis by inhibiting the RIP1/RIP3/MLKL and MAPK signaling pathways.
    Zhang W, Zheng X, Gong Y, Jiang T, Qiu J, Wu X, Lu F, Wang Z, Hong Z.
    Bioorg Chem; 2022 Mar; 120():105632. PubMed ID: 35074577
    [Abstract] [Full Text] [Related]

  • 2. Amentoflavone maintaining extracellular matrix homeostasis and inhibiting subchondral bone loss in osteoarthritis by inhibiting ERK, JNK and NF-κB signaling pathways.
    Liang J, Hu J, Hong X, Zhou M, Xia G, Hu L, Luo S, Quan K, Yan J, Wang S, Fan S.
    J Orthop Surg Res; 2024 Oct 15; 19(1):662. PubMed ID: 39407273
    [Abstract] [Full Text] [Related]

  • 3. Selumetinib - a potential small molecule inhibitor for osteoarthritis treatment.
    Zheng X, Qiu J, Pan W, Gong Y, Zhang W, Jiang T, Chen L, Chen W, Hong Z.
    Front Pharmacol; 2022 Oct 15; 13():938133. PubMed ID: 36238555
    [Abstract] [Full Text] [Related]

  • 4. Dihydroartemisinin attenuates osteoclast formation and bone resorption via inhibiting the NF‑κB, MAPK and NFATc1 signaling pathways and alleviates osteoarthritis.
    Ding D, Yan J, Feng G, Zhou Y, Ma L, Jin Q.
    Int J Mol Med; 2022 Jan 15; 49(1):. PubMed ID: 34738623
    [Abstract] [Full Text] [Related]

  • 5. PD0325901, an ERK inhibitor, attenuates RANKL-induced osteoclast formation and mitigates cartilage inflammation by inhibiting the NF-κB and MAPK pathways.
    Jiang T, Gong Y, Zhang W, Qiu J, Zheng X, Li Z, Yang G, Hong Z.
    Bioorg Chem; 2023 Mar 15; 132():106321. PubMed ID: 36642020
    [Abstract] [Full Text] [Related]

  • 6. Paroxetine Attenuates Chondrocyte Pyroptosis and Inhibits Osteoclast Formation by Inhibiting NF-κB Pathway Activation to Delay Osteoarthritis Progression.
    Zheng X, Qiu J, Gao N, Jiang T, Li Z, Zhang W, Gong Y, Hong Z, Hong H.
    Drug Des Devel Ther; 2023 Mar 15; 17():2383-2399. PubMed ID: 37605762
    [Abstract] [Full Text] [Related]

  • 7. Insulin-Like Growth Factor II (IGF-II) Inhibits IL-1β-Induced Cartilage Matrix Loss and Promotes Cartilage Integrity in Experimental Osteoarthritis.
    Uchimura T, Foote AT, Smith EL, Matzkin EG, Zeng L.
    J Cell Biochem; 2015 Dec 15; 116(12):2858-69. PubMed ID: 26015264
    [Abstract] [Full Text] [Related]

  • 8. Dual protective role of velutin against articular cartilage degeneration and subchondral bone loss via the p38 signaling pathway in murine osteoarthritis.
    Wang K, Lu X, Li X, Zhang Y, Xu R, Lou Y, Wang Y, Zhang T, Qian Y.
    Front Endocrinol (Lausanne); 2022 Dec 15; 13():926934. PubMed ID: 35937813
    [Abstract] [Full Text] [Related]

  • 9. Neratinib exerts dual effects on cartilage degradation and osteoclast production in Osteoarthritis by inhibiting the activation of the MAPK/NF-κB signaling pathways.
    Qiu J, Jiang T, Yang G, Gong Y, Zhang W, Zheng X, Hong Z, Chen H.
    Biochem Pharmacol; 2022 Nov 15; 205():115155. PubMed ID: 35820500
    [Abstract] [Full Text] [Related]

  • 10. Targeted inhibition of STAT3 (Tyr705) by xanthatin alleviates osteoarthritis progression through the NF-κB signaling pathway.
    Xu Y, Chen Z, Lu X, Zheng J, Liu X, Zhang T, Yang W, Qian Y.
    Biomed Pharmacother; 2024 May 15; 174():116451. PubMed ID: 38520869
    [Abstract] [Full Text] [Related]

  • 11. Zoledronic acid generates a spatiotemporal effect to attenuate osteoarthritis by inhibiting potential Wnt5a-associated abnormal subchondral bone resorption.
    Ding D, Wang L, Yan J, Zhou Y, Feng G, Ma L, Yang Y, Pei X, Jin Q.
    PLoS One; 2022 May 15; 17(7):e0271485. PubMed ID: 35900969
    [Abstract] [Full Text] [Related]

  • 12. Metformin attenuates osteoclast-mediated abnormal subchondral bone remodeling and alleviates osteoarthritis via AMPK/NF-κB/ERK signaling pathway.
    Guo H, Ding D, Wang L, Yan J, Ma L, Jin Q.
    PLoS One; 2021 May 15; 16(12):e0261127. PubMed ID: 34914744
    [Abstract] [Full Text] [Related]

  • 13. AZ-628 delays osteoarthritis progression via inhibiting the TNF-α-induced chondrocyte necroptosis and regulating osteoclast formation.
    Gong Y, Qiu J, Ye J, Jiang T, Zhang W, Zheng X, Zhu Z, Chen L, Wang Z, Mi S, Hong Z.
    Int Immunopharmacol; 2022 Oct 15; 111():109085. PubMed ID: 35952515
    [Abstract] [Full Text] [Related]

  • 14. Sinomenine contributes to the inhibition of the inflammatory response and the improvement of osteoarthritis in mouse-cartilage cells by acting on the Nrf2/HO-1 and NF-κB signaling pathways.
    Wu Y, Lin Z, Yan Z, Wang Z, Fu X, Yu K.
    Int Immunopharmacol; 2019 Oct 15; 75():105715. PubMed ID: 31310911
    [Abstract] [Full Text] [Related]

  • 15. Sotrastaurin, a PKC inhibitor, attenuates RANKL-induced bone resorption and attenuates osteochondral pathologies associated with the development of OA.
    Pang C, Wen L, Qin H, Zhu B, Lu X, Luo S.
    J Cell Mol Med; 2020 Aug 15; 24(15):8452-8465. PubMed ID: 32652826
    [Abstract] [Full Text] [Related]

  • 16. Anemonin attenuates osteoarthritis progression through inhibiting the activation of IL-1β/NF-κB pathway.
    Wang Z, Huang J, Zhou S, Luo F, Xu W, Wang Q, Tan Q, Chen L, Wang J, Chen H, Chen L, Xie Y, Du X.
    J Cell Mol Med; 2017 Dec 15; 21(12):3231-3243. PubMed ID: 28643466
    [Abstract] [Full Text] [Related]

  • 17. Lithium protects against cartilage degradation in osteoarthritis.
    Minashima T, Zhang Y, Lee Y, Kirsch T.
    Arthritis Rheumatol; 2014 May 15; 66(5):1228-36. PubMed ID: 24470226
    [Abstract] [Full Text] [Related]

  • 18. Aucubin Protects Chondrocytes Against IL-1β-Induced Apoptosis In Vitro And Inhibits Osteoarthritis In Mice Model.
    Wang BW, Jiang Y, Yao ZL, Chen PS, Yu B, Wang SN.
    Drug Des Devel Ther; 2019 May 15; 13():3529-3538. PubMed ID: 31631977
    [Abstract] [Full Text] [Related]

  • 19. Teriparatide ameliorates articular cartilage degradation and aberrant subchondral bone remodeling in DMM mice.
    Li G, Liu S, Chen Y, Xu H, Qi T, Xiong A, Wang D, Yu F, Weng J, Zeng H.
    J Orthop Translat; 2023 Jan 15; 38():241-255. PubMed ID: 36514714
    [Abstract] [Full Text] [Related]

  • 20. Morroniside attenuates apoptosis and pyroptosis of chondrocytes and ameliorates osteoarthritic development by inhibiting NF-κB signaling.
    Yu H, Yao S, Zhou C, Fu F, Luo H, Du W, Jin H, Tong P, Chen D, Wu C, Ruan H.
    J Ethnopharmacol; 2021 Feb 10; 266():113447. PubMed ID: 33022338
    [Abstract] [Full Text] [Related]

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