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Journal Abstract Search

323 related items for PubMed ID: 35109719

  • 1. Angiogenesis and anti-leukaemia activity of novel indole derivatives as potent colchicine binding site inhibitors.
    Yao Y, Huang T, Wang Y, Wang L, Feng S, Cheng W, Yang L, Duan Y.
    J Enzyme Inhib Med Chem; 2022 Dec; 37(1):652-665. PubMed ID: 35109719
    [Abstract] [Full Text] [Related]

  • 2. Identification of novel non-toxic and anti-angiogenic α-fluorinated chalcones as potent colchicine binding site inhibitors.
    Sun M, Yuan M, Kang Y, Qin J, Zhang Y, Duan Y, Wang L, Yao Y.
    J Enzyme Inhib Med Chem; 2022 Dec; 37(1):339-354. PubMed ID: 34979843
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of new 2-methoxyestradiol derivatives: Potent inhibitors of angiogenesis and tubulin polymerization.
    Sun M, Zhang Y, Qin J, Ba M, Yao Y, Duan Y, Liu H, Yu D.
    Bioorg Chem; 2021 Aug; 113():104988. PubMed ID: 34034135
    [Abstract] [Full Text] [Related]

  • 4. Discovery of novel tubulin/HDAC dual-targeting inhibitors with strong antitumor and antiangiogenic potency.
    Wang Y, Sun M, Wang Y, Qin J, Zhang Y, Pang Y, Yao Y, Yang H, Duan Y.
    Eur J Med Chem; 2021 Dec 05; 225():113790. PubMed ID: 34454126
    [Abstract] [Full Text] [Related]

  • 5. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
    Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH.
    J Enzyme Inhib Med Chem; 2021 Dec 05; 36(1):640-658. PubMed ID: 33588683
    [Abstract] [Full Text] [Related]

  • 6. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 05; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding site.
    Wang G, Liu W, Gong Z, Huang Y, Li Y, Peng Z.
    J Enzyme Inhib Med Chem; 2020 Dec 05; 35(1):139-144. PubMed ID: 31724435
    [Abstract] [Full Text] [Related]

  • 8. Identification of new 3-phenyl-1H-indole-2-carbohydrazide derivatives and their structure-activity relationships as potent tubulin inhibitors and anticancer agents: A combined in silico, in vitro and synthetic study.
    Saruengkhanphasit R, Butkinaree C, Ornnork N, Lirdprapamongkol K, Niwetmarin W, Svasti J, Ruchirawat S, Eurtivong C.
    Bioorg Chem; 2021 May 05; 110():104795. PubMed ID: 33730670
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site.
    Li W, Shuai W, Sun H, Xu F, Bi Y, Xu J, Ma C, Yao H, Zhu Z, Xu S.
    Eur J Med Chem; 2019 Feb 01; 163():428-442. PubMed ID: 30530194
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V, Pindiprolu SKSS, Sana S, Ramamurty DSVNM, Madasi JRK, Vadlamani S.
    Anticancer Agents Med Chem; 2021 Feb 01; 21(8):1047-1055. PubMed ID: 32981511
    [Abstract] [Full Text] [Related]

  • 11. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
    Liu YN, Wang JJ, Ji YT, Zhao GD, Tang LQ, Zhang CM, Guo XL, Liu ZP.
    J Med Chem; 2016 Jun 09; 59(11):5341-55. PubMed ID: 27172319
    [Abstract] [Full Text] [Related]

  • 12. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP, Wu CY, Hsieh HP, Chang CY, Chen CM, Kuo CC, Chang JY.
    J Med Chem; 2007 Sep 06; 50(18):4548-52. PubMed ID: 17685504
    [Abstract] [Full Text] [Related]

  • 13. New indolesulfonamide derivatives targeting the colchicine site of tubulin: synthesis, anti-tumour activity, structure-activity relationships, and molecular modelling.
    Vicente-Blázquez A, González M, Medarde M, Mollinedo F, Peláez R.
    J Enzyme Inhib Med Chem; 2021 Dec 06; 36(1):2025-2044. PubMed ID: 34514909
    [Abstract] [Full Text] [Related]

  • 14. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.
    Cui YJ, Ma CC, Zhang CM, Tang LQ, Liu ZP.
    Eur J Med Chem; 2020 Feb 01; 187():111968. PubMed ID: 31865012
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 16. Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance.
    Cheng B, Zhu G, Meng L, Wu G, Chen Q, Ma S.
    Eur J Med Chem; 2022 Jan 15; 228():113930. PubMed ID: 34794817
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and biological evaluation of novel thiazole-naphthalene derivatives as potential anticancer agents and tubulin polymerisation inhibitors.
    Wang G, Liu W, Fan M, He M, Li Y, Peng Z.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):1694-1702. PubMed ID: 34309466
    [Abstract] [Full Text] [Related]

  • 18. Antiproliferative benzothiazoles incorporating a trimethoxyphenyl scaffold as novel colchicine site tubulin polymerisation inhibitors.
    Fu DJ, Liu SM, Li FH, Yang JJ, Li J.
    J Enzyme Inhib Med Chem; 2020 Dec 15; 35(1):1050-1059. PubMed ID: 32299262
    [Abstract] [Full Text] [Related]

  • 19. Discovery of indoline derivatives as anticancer agents via inhibition of tubulin polymerization.
    Wang SY, Liu X, Meng LW, Li MM, Li YR, Yu GX, Song J, Zhang HY, Chen P, Zhang SY, Hu T.
    Bioorg Med Chem Lett; 2021 Jul 01; 43():128095. PubMed ID: 33965530
    [Abstract] [Full Text] [Related]

  • 20. Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site.
    Li W, Sun H, Xu F, Shuai W, Liu J, Xu S, Yao H, Ma C, Zhu Z, Xu J.
    Bioorg Chem; 2019 Apr 01; 85():49-59. PubMed ID: 30599412
    [Abstract] [Full Text] [Related]

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