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Journal Abstract Search

168 related items for PubMed ID: 35153334

  • 1. Protein-protein interaction of RdRp with its co-factor NSP8 and NSP7 to decipher the interface hotspot residues for drug targeting: A comparison between SARS-CoV-2 and SARS-CoV.
    Sarma H, Jamir E, Sastry GN.
    J Mol Struct; 2022 Jun 05; 1257():132602. PubMed ID: 35153334
    [Abstract] [Full Text] [Related]

  • 2. Investigation of protein-protein interactions and hotspot region on the NSP7-NSP8 binding site in NSP12 of SARS-CoV-2.
    Lima Neto JX, Bezerra KS, Barbosa ED, Araujo RL, Galvão DS, Lyra ML, Oliveira JIN, Akash S, Jardan YAB, Nafidi HA, Bourhia M, Fulco UL.
    Front Mol Biosci; 2023 Jun 05; 10():1325588. PubMed ID: 38304231
    [Abstract] [Full Text] [Related]

  • 3. Two conserved oligomer interfaces of NSP7 and NSP8 underpin the dynamic assembly of SARS-CoV-2 RdRP.
    Biswal M, Diggs S, Xu D, Khudaverdyan N, Lu J, Fang J, Blaha G, Hai R, Song J.
    Nucleic Acids Res; 2021 Jun 04; 49(10):5956-5966. PubMed ID: 33999154
    [Abstract] [Full Text] [Related]

  • 4. Resolving the Dynamic Motions of SARS-CoV-2 nsp7 and nsp8 Proteins Using Structural Proteomics.
    Courouble VV, Dey SK, Yadav R, Timm J, Harrison JJEK, Ruiz FX, Arnold E, Griffin PR.
    bioRxiv; 2021 Mar 06. PubMed ID: 33688660
    [Abstract] [Full Text] [Related]

  • 5. Revealing the Structural Plasticity of SARS-CoV-2 nsp7 and nsp8 Using Structural Proteomics.
    Courouble VV, Dey SK, Yadav R, Timm J, Harrison JJEK, Ruiz FX, Arnold E, Griffin PR.
    J Am Soc Mass Spectrom; 2021 Jul 07; 32(7):1618-1630. PubMed ID: 34121407
    [Abstract] [Full Text] [Related]

  • 6. SARS-CoV-2 and SARS-CoV: Virtual screening of potential inhibitors targeting RNA-dependent RNA polymerase activity (NSP12).
    Ruan Z, Liu C, Guo Y, He Z, Huang X, Jia X, Yang T.
    J Med Virol; 2021 Jan 07; 93(1):389-400. PubMed ID: 32579254
    [Abstract] [Full Text] [Related]

  • 7. A Computational Study on the Interaction of NSP10 and NSP14: Unraveling the RNA Synthesis Proofreading Mechanism in SARS-CoV-2, SARS-CoV, and MERS-CoV.
    Sarma H, Sastry GN.
    ACS Omega; 2022 Aug 30; 7(34):30003-30022. PubMed ID: 36035077
    [Abstract] [Full Text] [Related]

  • 8. Peptide inhibitors derived from the nsp7 and nsp8 cofactors of nsp12 targeting different substrate binding sites of nsp12 of the SARS-CoV-2.
    Jena NR, Pant S.
    J Biomol Struct Dyn; 2024 Aug 30; 42(13):7077-7089. PubMed ID: 37434315
    [Abstract] [Full Text] [Related]

  • 9. Mutations in SARS-CoV-2 nsp7 and nsp8 proteins and their predicted impact on replication/transcription complex structure.
    Reshamwala SMS, Likhite V, Degani MS, Deb SS, Noronha SB.
    J Med Virol; 2021 Jul 30; 93(7):4616-4619. PubMed ID: 33433004
    [Abstract] [Full Text] [Related]

  • 10. Targeting SARS-CoV-2 Nsp12/Nsp8 interaction interface with approved and investigational drugs: an in silico structure-based approach.
    Mutlu O, Ugurel OM, Sariyer E, Ata O, Inci TG, Ugurel E, Kocer S, Turgut-Balik D.
    J Biomol Struct Dyn; 2022 Feb 30; 40(2):918-930. PubMed ID: 32933378
    [Abstract] [Full Text] [Related]

  • 11. Interface design of SARS-CoV-2 symmetrical nsp7 dimer and machine learning-guided nsp7 sequence prediction reveals physicochemical properties and hotspots for nsp7 stability, adaptation, and therapeutic design.
    Yadav AJ, Kumar S, Maurya S, Bhagat K, Padhi AK.
    Phys Chem Chem Phys; 2024 May 08; 26(18):14046-14061. PubMed ID: 38686454
    [Abstract] [Full Text] [Related]

  • 12. An efficient computational protocol for template-based design of peptides that inhibit interactions involving SARS-CoV-2 proteins.
    Chenna A, Khan WH, Dash R, Saraswat S, Chugh A, Rathore AS, Goel G.
    Proteins; 2023 Sep 08; 91(9):1222-1234. PubMed ID: 37283297
    [Abstract] [Full Text] [Related]

  • 13. Point mutations at specific sites of the nsp12-nsp8 interface dramatically affect the RNA polymerization activity of SARS-CoV-2.
    Ferrer-Orta C, Vázquez-Monteagudo S, Ferrero DS, Martínez-González B, Perales C, Domingo E, Verdaguer N.
    Proc Natl Acad Sci U S A; 2024 Jul 16; 121(29):e2317977121. PubMed ID: 38990941
    [Abstract] [Full Text] [Related]

  • 14. Potential inhibitors of SARS-cov-2 RNA dependent RNA polymerase protein: molecular docking, molecular dynamics simulations and MM-PBSA analyses.
    Elkarhat Z, Charoute H, Elkhattabi L, Barakat A, Rouba H.
    J Biomol Struct Dyn; 2022 Jan 16; 40(1):361-374. PubMed ID: 32873176
    [Abstract] [Full Text] [Related]

  • 15. Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication.
    Wilamowski M, Hammel M, Leite W, Zhang Q, Kim Y, Weiss KL, Jedrzejczak R, Rosenberg DJ, Fan Y, Wower J, Bierma JC, Sarker AH, Tsutakawa SE, Pingali SV, O'Neill HM, Joachimiak A, Hura GL.
    Biophys J; 2021 Aug 03; 120(15):3152-3165. PubMed ID: 34197805
    [Abstract] [Full Text] [Related]

  • 16. The E3 ligase TRIM22 restricts SARS-CoV-2 replication by promoting proteasomal degradation of NSP8.
    Fan L, Zhou Y, Wei X, Feng W, Guo H, Li Y, Gao X, Zhou J, Wen Y, Wu Y, Shen X, Liu L, Xu G, Zhang Z.
    mBio; 2024 Feb 14; 15(2):e0232023. PubMed ID: 38275298
    [Abstract] [Full Text] [Related]

  • 17. Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.
    Wang Q, Wu J, Wang H, Gao Y, Liu Q, Mu A, Ji W, Yan L, Zhu Y, Zhu C, Fang X, Yang X, Huang Y, Gao H, Liu F, Ge J, Sun Q, Yang X, Xu W, Liu Z, Yang H, Lou Z, Jiang B, Guddat LW, Gong P, Rao Z.
    Cell; 2020 Jul 23; 182(2):417-428.e13. PubMed ID: 32526208
    [Abstract] [Full Text] [Related]

  • 18. One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities.
    Subissi L, Posthuma CC, Collet A, Zevenhoven-Dobbe JC, Gorbalenya AE, Decroly E, Snijder EJ, Canard B, Imbert I.
    Proc Natl Acad Sci U S A; 2014 Sep 16; 111(37):E3900-9. PubMed ID: 25197083
    [Abstract] [Full Text] [Related]

  • 19. Bio-Chemoinformatics-Driven Analysis of nsp7 and nsp8 Mutations and Their Effects on Viral Replication Protein Complex Stability.
    Subong BJJ, Ozawa T.
    Curr Issues Mol Biol; 2024 Mar 18; 46(3):2598-2619. PubMed ID: 38534781
    [Abstract] [Full Text] [Related]

  • 20. Revealing the structural and molecular interaction landscape of the favipiravir-RTP and SARS-CoV-2 RdRp complex through integrative bioinformatics: Insights for developing potent drugs targeting SARS-CoV-2 and other viruses.
    Chakraborty C, Bhattacharya M, Saha A, Alshammari A, Alharbi M, Saikumar G, Pal S, Dhama K, Lee SS.
    J Infect Public Health; 2023 Jul 18; 16(7):1048-1056. PubMed ID: 37196368
    [Abstract] [Full Text] [Related]

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