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Journal Abstract Search
277 related items for PubMed ID: 35154073
1. The One That Got Away: How Macrophage-Derived IL-1β Escapes the Mycolactone-Dependent Sec61 Blockade in Buruli Ulcer. Hall BS, Hsieh LT, Sacre S, Simmonds RE. Front Immunol; 2021; 12():788146. PubMed ID: 35154073 [Abstract] [Full Text] [Related]
2. Mechanistic insights into the inhibition of Sec61-dependent co- and post-translational translocation by mycolactone. McKenna M, Simmonds RE, High S. J Cell Sci; 2016 Apr 01; 129(7):1404-15. PubMed ID: 26869228 [Abstract] [Full Text] [Related]
3. Sec61 blockade by mycolactone: A central mechanism in Buruli ulcer disease. Demangel C, High S. Biol Cell; 2018 Nov 01; 110(11):237-248. PubMed ID: 30055020 [Abstract] [Full Text] [Related]
4. Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1β, are linked to fibrin formation in Buruli ulcer lesions. Hsieh LT, Dos Santos SJ, Hall BS, Ogbechi J, Loglo AD, Salguero FJ, Ruf MT, Pluschke G, Simmonds RE. PLoS Pathog; 2022 Jan 01; 18(1):e1010280. PubMed ID: 35100311 [Abstract] [Full Text] [Related]
5. Inflammasome-triggered IL-18 controls skin inflammation in the progression of Buruli ulcer. Suzuki T, Boonyaleka K, Okano T, Iida T, Yoshida M, Fukano H, Hoshino Y, Iwakura Y, Ablordey AS, Ashida H. PLoS Pathog; 2023 Nov 01; 19(11):e1011747. PubMed ID: 37910490 [Abstract] [Full Text] [Related]
6. Immunity against Mycobacterium ulcerans: The subversive role of mycolactone. Demangel C. Immunol Rev; 2021 May 01; 301(1):209-221. PubMed ID: 33607704 [Abstract] [Full Text] [Related]
7. The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER. Hall BS, Hill K, McKenna M, Ogbechi J, High S, Willis AE, Simmonds RE. PLoS Pathog; 2014 Apr 01; 10(4):e1004061. PubMed ID: 24699819 [Abstract] [Full Text] [Related]
8. Mycolactone toxin induces an inflammatory response by targeting the IL-1β pathway: Mechanistic insight into Buruli ulcer pathophysiology. Foulon M, Robbe-Saule M, Manry J, Esnault L, Boucaud Y, Alcaïs A, Malloci M, Fanton d'Andon M, Beauvais T, Labarriere N, Jeannin P, Abel L, Saint-André JP, Croué A, Delneste Y, Boneca IG, Marsollier L, Marion E. PLoS Pathog; 2020 Dec 01; 16(12):e1009107. PubMed ID: 33338061 [Abstract] [Full Text] [Related]
9. Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity. Hall BS, Dos Santos SJ, Hsieh LT, Manifava M, Ruf MT, Pluschke G, Ktistakis N, Simmonds RE. Autophagy; 2022 Apr 01; 18(4):841-859. PubMed ID: 34424124 [Abstract] [Full Text] [Related]
10. Cellular immunity confers transient protection in experimental Buruli ulcer following BCG or mycolactone-negative Mycobacterium ulcerans vaccination. Fraga AG, Martins TG, Torrado E, Huygen K, Portaels F, Silva MT, Castro AG, Pedrosa J. PLoS One; 2012 Apr 01; 7(3):e33406. PubMed ID: 22413022 [Abstract] [Full Text] [Related]
11. Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions. Ogbechi J, Ruf MT, Hall BS, Bodman-Smith K, Vogel M, Wu HL, Stainer A, Esmon CT, Ahnström J, Pluschke G, Simmonds RE. PLoS Pathog; 2015 Jul 01; 11(7):e1005011. PubMed ID: 26181660 [Abstract] [Full Text] [Related]
13. Mycolactone A vs. B: Multiscale Simulations Reveal the Roles of Localization and Association in Isomer-Specific Toxicity. Nguyen JDM, da Hora GCA, Swanson JMJ. Toxins (Basel); 2023 Aug 02; 15(8):. PubMed ID: 37624243 [Abstract] [Full Text] [Related]
14. Molecular Docking and Dynamics Simulation Studies Predict Munc18b as a Target of Mycolactone: A Plausible Mechanism for Granule Exocytosis Impairment in Buruli Ulcer Pathogenesis. Kwofie SK, Dankwa B, Enninful KS, Adobor C, Broni E, Ntiamoah A, Wilson MD. Toxins (Basel); 2019 Mar 25; 11(3):. PubMed ID: 30934618 [Abstract] [Full Text] [Related]
15. Mycolactone reveals the substrate-driven complexity of Sec61-dependent transmembrane protein biogenesis. McKenna M, Simmonds RE, High S. J Cell Sci; 2017 Apr 01; 130(7):1307-1320. PubMed ID: 28219954 [Abstract] [Full Text] [Related]
16. Structure of the Inhibited State of the Sec Translocon. Gérard SF, Hall BS, Zaki AM, Corfield KA, Mayerhofer PU, Costa C, Whelligan DK, Biggin PC, Simmonds RE, Higgins MK. Mol Cell; 2020 Aug 06; 79(3):406-415.e7. PubMed ID: 32692975 [Abstract] [Full Text] [Related]
17. Mycolactone enhances the Ca2+ leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state. Bhadra P, Dos Santos S, Gamayun I, Pick T, Neumann C, Ogbechi J, Hall BS, Zimmermann R, Helms V, Simmonds RE, Cavalié A. Biochem J; 2021 Nov 26; 478(22):4005-4024. PubMed ID: 34726690 [Abstract] [Full Text] [Related]