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Journal Abstract Search

641 related items for PubMed ID: 35164325

  • 1. Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N-Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile.
    Makhaeva GF, Kovaleva NV, Boltneva NP, Rudakova EV, Lushchekina SV, Astakhova TY, Serkov IV, Proshin AN, Radchenko EV, Palyulin VA, Korabecny J, Soukup O, Bachurin SO, Richardson RJ.
    Molecules; 2022 Feb 04; 27(3):. PubMed ID: 35164325
    [Abstract] [Full Text] [Related]

  • 2. Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment.
    Makhaeva GF, Lushchekina SV, Kovaleva NV, Yu Astakhova T, Boltneva NP, Rudakova EV, Serebryakova OG, Proshin AN, Serkov IV, Trofimova TP, Tafeenko VA, Radchenko EV, Palyulin VA, Fisenko VP, Korábečný J, Soukup O, Richardson RJ.
    Bioorg Chem; 2021 Jul 04; 112():104974. PubMed ID: 34029971
    [Abstract] [Full Text] [Related]

  • 3. Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease.
    Makhaeva GF, Kovaleva NV, Rudakova EV, Boltneva NP, Grishchenko MV, Lushchekina SV, Astakhova TY, Serebryakova OG, Timokhina EN, Zhilina EF, Shchegolkov EV, Ulitko MV, Radchenko EV, Palyulin VA, Burgart YV, Saloutin VI, Bachurin SO, Richardson RJ.
    Int J Mol Sci; 2023 Jan 24; 24(3):. PubMed ID: 36768608
    [Abstract] [Full Text] [Related]

  • 4. New Hybrids of 4-Amino-2,3-polymethylene-quinoline and p-Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Alzheimer's Disease Treatment.
    Makhaeva GF, Kovaleva NV, Boltneva NP, Lushchekina SV, Astakhova TY, Rudakova EV, Proshin AN, Serkov IV, Radchenko EV, Palyulin VA, Bachurin SO, Richardson RJ.
    Molecules; 2020 Aug 27; 25(17):. PubMed ID: 32867324
    [Abstract] [Full Text] [Related]

  • 5. New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer's Disease Treatment.
    Makhaeva GF, Kovaleva NV, Rudakova EV, Boltneva NP, Lushchekina SV, Faingold II, Poletaeva DA, Soldatova YV, Kotelnikova RA, Serkov IV, Ustinov AK, Proshin AN, Radchenko EV, Palyulin VA, Richardson RJ.
    Molecules; 2020 Dec 12; 25(24):. PubMed ID: 33322783
    [Abstract] [Full Text] [Related]

  • 6. Conjugates of tacrine and 1,2,4-thiadiazole derivatives as new potential multifunctional agents for Alzheimer's disease treatment: Synthesis, quantum-chemical characterization, molecular docking, and biological evaluation.
    Makhaeva GF, Kovaleva NV, Boltneva NP, Lushchekina SV, Rudakova EV, Stupina TS, Terentiev AA, Serkov IV, Proshin AN, Radchenko EV, Palyulin VA, Bachurin SO, Richardson RJ.
    Bioorg Chem; 2020 Jan 12; 94():103387. PubMed ID: 31735356
    [Abstract] [Full Text] [Related]

  • 7. Conjugates of Tacrine with Salicylamide as Promising Multitarget Agents for Alzheimer's Disease.
    Grishchenko MV, Makhaeva GF, Burgart YV, Rudakova EV, Boltneva NP, Kovaleva NV, Serebryakova OG, Lushchekina SV, Astakhova TY, Zhilina EF, Shchegolkov EV, Richardson RJ, Saloutin VI.
    ChemMedChem; 2022 May 18; 17(10):e202200080. PubMed ID: 35322571
    [Abstract] [Full Text] [Related]

  • 8. New Multifunctional Agents for Potential Alzheimer's Disease Treatment Based on Tacrine Conjugates with 2-Arylhydrazinylidene-1,3-Diketones.
    Elkina NA, Grishchenko MV, Shchegolkov EV, Makhaeva GF, Kovaleva NV, Rudakova EV, Boltneva NP, Lushchekina SV, Astakhova TY, Radchenko EV, Palyulin VA, Zhilina EF, Perminova AN, Lapshin LS, Burgart YV, Saloutin VI, Richardson RJ.
    Biomolecules; 2022 Oct 24; 12(11):. PubMed ID: 36358901
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis, and evaluation of novel cinnamic acid-tryptamine hybrid for inhibition of acetylcholinesterase and butyrylcholinesterase.
    Ghafary S, Ghobadian R, Mahdavi M, Nadri H, Moradi A, Akbarzadeh T, Najafi Z, Sharifzadeh M, Edraki N, Moghadam FH, Amini M.
    Daru; 2020 Dec 24; 28(2):463-477. PubMed ID: 32372339
    [Abstract] [Full Text] [Related]

  • 10. Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents.
    Shaik JB, Palaka BK, Penumala M, Kotapati KV, Devineni SR, Eadlapalli S, Darla MM, Ampasala DR, Vadde R, Amooru GD.
    Eur J Med Chem; 2016 Jan 01; 107():219-32. PubMed ID: 26588065
    [Abstract] [Full Text] [Related]

  • 11. Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease.
    Singh YP, Shankar G, Jahan S, Singh G, Kumar N, Barik A, Upadhyay P, Singh L, Kamble K, Singh GK, Tiwari S, Garg P, Gupta S, Modi G.
    Bioorg Med Chem; 2021 Sep 15; 46():116385. PubMed ID: 34481338
    [Abstract] [Full Text] [Related]

  • 12. Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents.
    Maqbool M, Manral A, Jameel E, Kumar J, Saini V, Shandilya A, Tiwari M, Hoda N, Jayaram B.
    Bioorg Med Chem; 2016 Jun 15; 24(12):2777-88. PubMed ID: 27157006
    [Abstract] [Full Text] [Related]

  • 13. Design, Synthesis, and Evaluation of Acetylcholinesterase and Butyrylcholinesterase Dual-Target Inhibitors against Alzheimer's Diseases.
    Guo Y, Yang H, Huang Z, Tian S, Li Q, Du C, Chen T, Liu Y, Sun H, Liu Z.
    Molecules; 2020 Jan 23; 25(3):. PubMed ID: 31979317
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis, and biological evaluation of ferulic acid based 1,3,4-oxadiazole hybrids as multifunctional therapeutics for the treatment of Alzheimer's disease.
    Tripathi A, Choubey PK, Sharma P, Seth A, Saraf P, Shrivastava SK.
    Bioorg Chem; 2020 Jan 23; 95():103506. PubMed ID: 31887472
    [Abstract] [Full Text] [Related]

  • 15. Novel tacrine-based acetylcholinesterase inhibitors as potential agents for the treatment of Alzheimer's disease: Quinolotacrine hybrids.
    Sadafi Kohnehshahri M, Chehardoli G, Bahiraei M, Akbarzadeh T, Ranjbar A, Rastegari A, Najafi Z.
    Mol Divers; 2022 Feb 23; 26(1):489-503. PubMed ID: 34491490
    [Abstract] [Full Text] [Related]

  • 16. Overview of novel multifunctional agents based on conjugates of γ-carbolines, carbazoles, tetrahydrocarbazoles, phenothiazines, and aminoadamantanes for treatment of Alzheimer's disease.
    Makhaeva GF, Shevtsova EF, Boltneva NP, Lushchekina SV, Kovaleva NV, Rudakova EV, Bachurin SO, Richardson RJ.
    Chem Biol Interact; 2019 Aug 01; 308():224-234. PubMed ID: 31100279
    [Abstract] [Full Text] [Related]

  • 17. 9-Substituted acridine derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors possessing antioxidant activity for Alzheimer's disease treatment.
    Makhaeva GF, Lushchekina SV, Boltneva NP, Serebryakova OG, Rudakova EV, Ustyugov AA, Bachurin SO, Shchepochkin AV, Chupakhin ON, Charushin VN, Richardson RJ.
    Bioorg Med Chem; 2017 Nov 01; 25(21):5981-5994. PubMed ID: 28986116
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis, evaluation and molecular modeling study of 4-N-phenylaminoquinolines for Alzheimer disease treatment.
    Zhu J, Wang LN, Cai R, Geng SQ, Dong YF, Liu YM.
    Bioorg Med Chem Lett; 2019 Jun 01; 29(11):1325-1329. PubMed ID: 30956012
    [Abstract] [Full Text] [Related]

  • 19. Design and development of molecular hybrids of 2-pyridylpiperazine and 5-phenyl-1,3,4-oxadiazoles as potential multifunctional agents to treat Alzheimer's disease.
    Tripathi A, Choubey PK, Sharma P, Seth A, Tripathi PN, Tripathi MK, Prajapati SK, Krishnamurthy S, Shrivastava SK.
    Eur J Med Chem; 2019 Dec 01; 183():111707. PubMed ID: 31561043
    [Abstract] [Full Text] [Related]

  • 20. Pharmacophore-based drug design of AChE and BChE dual inhibitors as potential anti-Alzheimer's disease agents.
    Gao H, Jiang Y, Zhan J, Sun Y.
    Bioorg Chem; 2021 Sep 01; 114():105149. PubMed ID: 34252860
    [Abstract] [Full Text] [Related]

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