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Journal Abstract Search

336 related items for PubMed ID: 35194903

  • 1. XRCC1 counteracts poly(ADP ribose)polymerase (PARP) poisons, olaparib and talazoparib, and a clinical alkylating agent, temozolomide, by promoting the removal of trapped PARP1 from broken DNA.
    Hirota K, Ooka M, Shimizu N, Yamada K, Tsuda M, Ibrahim MA, Yamada S, Sasanuma H, Masutani M, Takeda S.
    Genes Cells; 2022 May; 27(5):331-344. PubMed ID: 35194903
    [Abstract] [Full Text] [Related]

  • 2. Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate.
    Ström CE, Johansson F, Uhlén M, Szigyarto CA, Erixon K, Helleday T.
    Nucleic Acids Res; 2011 Apr; 39(8):3166-75. PubMed ID: 21183466
    [Abstract] [Full Text] [Related]

  • 3. Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity.
    Saville KM, Al-Rahahleh RQ, Siddiqui AH, Andrews ME, Roos WP, Koczor CA, Andrews JF, Hayat F, Migaud ME, Sobol RW.
    DNA Repair (Amst); 2024 Aug; 140():103700. PubMed ID: 38897003
    [Abstract] [Full Text] [Related]

  • 4. Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses.
    Horton JK, Stefanick DF, Gassman NR, Williams JG, Gabel SA, Cuneo MJ, Prasad R, Kedar PS, Derose EF, Hou EW, London RE, Wilson SH.
    DNA Repair (Amst); 2013 Sep; 12(9):774-85. PubMed ID: 23871146
    [Abstract] [Full Text] [Related]

  • 5. XRCC1 prevents toxic PARP1 trapping during DNA base excision repair.
    Demin AA, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, Gittens W, Kalasova I, Shao Z, Zha S, Sasanuma H, Hanzlikova H, Takeda S, Caldecott KW.
    Mol Cell; 2021 Jul 15; 81(14):3018-3030.e5. PubMed ID: 34102106
    [Abstract] [Full Text] [Related]

  • 6. Stereospecific PARP trapping by BMN 673 and comparison with olaparib and rucaparib.
    Murai J, Huang SY, Renaud A, Zhang Y, Ji J, Takeda S, Morris J, Teicher B, Doroshow JH, Pommier Y.
    Mol Cancer Ther; 2014 Feb 15; 13(2):433-43. PubMed ID: 24356813
    [Abstract] [Full Text] [Related]

  • 7. Mechanistic Dissection of PARP1 Trapping and the Impact on In Vivo Tolerability and Efficacy of PARP Inhibitors.
    Hopkins TA, Shi Y, Rodriguez LE, Solomon LR, Donawho CK, DiGiammarino EL, Panchal SC, Wilsbacher JL, Gao W, Olson AM, Stolarik DF, Osterling DJ, Johnson EF, Maag D.
    Mol Cancer Res; 2015 Nov 15; 13(11):1465-77. PubMed ID: 26217019
    [Abstract] [Full Text] [Related]

  • 8. DNA polymerase β-dependent cell survival independent of XRCC1 expression.
    Horton JK, Gassman NR, Dunigan BD, Stefanick DF, Wilson SH.
    DNA Repair (Amst); 2015 Feb 15; 26():23-9. PubMed ID: 25541391
    [Abstract] [Full Text] [Related]

  • 9. [Influence of the Poly(ADP-Ribose) Polymerase 1 Level on the Status of Base Excision Repair in Human Cells].
    Ilina ES, Kochetkova AS, Belousova EA, Kutuzov MM, Lavrik OI, Khodyreva SN.
    Mol Biol (Mosk); 2023 Feb 15; 57(2):285-298. PubMed ID: 37000656
    [Abstract] [Full Text] [Related]

  • 10. Temporal recruitment of base excision DNA repair factors in living cells in response to different micro-irradiation DNA damage protocols.
    Zhao ML, Stefanick DF, Nadalutti CA, Beard WA, Wilson SH, Horton JK.
    DNA Repair (Amst); 2023 Jun 15; 126():103486. PubMed ID: 37028218
    [Abstract] [Full Text] [Related]

  • 11. Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis.
    Koczor CA, Saville KM, Andrews JF, Clark J, Fang Q, Li J, Al-Rahahleh RQ, Ibrahim M, McClellan S, Makarov MV, Migaud ME, Sobol RW.
    Cell Rep; 2021 Nov 02; 37(5):109917. PubMed ID: 34731617
    [Abstract] [Full Text] [Related]

  • 12. ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair.
    Tsuda M, Cho K, Ooka M, Shimizu N, Watanabe R, Yasui A, Nakazawa Y, Ogi T, Harada H, Agama K, Nakamura J, Asada R, Fujiike H, Sakuma T, Yamamoto T, Murai J, Hiraoka M, Koike K, Pommier Y, Takeda S, Hirota K.
    PLoS One; 2017 Nov 02; 12(11):e0188320. PubMed ID: 29149203
    [Abstract] [Full Text] [Related]

  • 13. [Effect and Mechanism of Radiosensitization of Poly (ADP-Ribose) Polymerase Inhibitor n Lewis Cells and Xenografts].
    Wang W, Duan B, Zeng L.
    Zhongguo Fei Ai Za Zhi; 2016 Jan 02; 19(1):16-23. PubMed ID: 26805733
    [Abstract] [Full Text] [Related]

  • 14. p21CDKN1A Regulates the Binding of Poly(ADP-Ribose) Polymerase-1 to DNA Repair Intermediates.
    Dutto I, Sukhanova M, Tillhon M, Cazzalini O, Stivala LA, Scovassi AI, Lavrik O, Prosperi E.
    PLoS One; 2016 Jan 02; 11(1):e0146031. PubMed ID: 26730949
    [Abstract] [Full Text] [Related]

  • 15. HMGA2 as a functional antagonist of PARP1 inhibitors in tumor cells.
    Hombach-Klonisch S, Kalantari F, Medapati MR, Natarajan S, Krishnan SN, Kumar-Kanojia A, Thanasupawat T, Begum F, Xu FY, Hatch GM, Los M, Klonisch T.
    Mol Oncol; 2019 Feb 02; 13(2):153-170. PubMed ID: 30289618
    [Abstract] [Full Text] [Related]

  • 16. PARP1 blockade is synthetically lethal in XRCC1 deficient sporadic epithelial ovarian cancers.
    Ali R, Alabdullah M, Alblihy A, Miligy I, Mesquita KA, Chan SY, Moseley P, Rakha EA, Madhusudan S.
    Cancer Lett; 2020 Jan 28; 469():124-133. PubMed ID: 31669203
    [Abstract] [Full Text] [Related]

  • 17. Disruption of PARP1 function inhibits base excision repair of a sub-set of DNA lesions.
    Reynolds P, Cooper S, Lomax M, O'Neill P.
    Nucleic Acids Res; 2015 Apr 30; 43(8):4028-38. PubMed ID: 25813046
    [Abstract] [Full Text] [Related]

  • 18. Olaparib and temozolomide in desmoplastic small round cell tumors: a promising combination in vitro and in vivo.
    van Erp AEM, van Houdt L, Hillebrandt-Roeffen MHS, van Bree NFHN, Flucke UE, Mentzel T, Shipley J, Desar IME, Fleuren EDG, Versleijen-Jonkers YMH, van der Graaf WTA.
    J Cancer Res Clin Oncol; 2020 Jul 30; 146(7):1659-1670. PubMed ID: 32279088
    [Abstract] [Full Text] [Related]

  • 19. Poly(ADP-ribose) polymerase 1 regulates activity of DNA polymerase beta in long patch base excision repair.
    Sukhanova M, Khodyreva S, Lavrik O.
    Mutat Res; 2010 Mar 01; 685(1-2):80-9. PubMed ID: 19703477
    [Abstract] [Full Text] [Related]

  • 20. Functional Roles of PARP2 in Assembling Protein-Protein Complexes Involved in Base Excision DNA Repair.
    Vasil'eva I, Moor N, Anarbaev R, Kutuzov M, Lavrik O.
    Int J Mol Sci; 2021 Apr 28; 22(9):. PubMed ID: 33925170
    [Abstract] [Full Text] [Related]

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