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499 related items for PubMed ID: 35248377

  • 1. Overactivation of hepatic mechanistic target of rapamycin kinase complex 1 (mTORC1) is associated with low transcriptional activity of transcription factor EB and lysosomal dysfunction in dairy cows with clinical ketosis.
    Fang Z, Li X, Wang S, Jiang Q, Loor JJ, Jiang X, Ju L, Yu H, Shen T, Chen M, Song Y, Wang Z, Du X, Liu G.
    J Dairy Sci; 2022 May; 105(5):4520-4533. PubMed ID: 35248377
    [Abstract] [Full Text] [Related]

  • 2. Evaluation of hepatic AMPK, mTORC1, and autophagy-lysosomal pathway in cows with mild or moderate fatty liver.
    Du X, Chen M, Fang Z, Shao Q, Yu H, Hao X, Gao X, Ju L, Li C, Yang Y, Song Y, Lei L, Liu G, Li X.
    J Dairy Sci; 2024 May; 107(5):3269-3279. PubMed ID: 37977448
    [Abstract] [Full Text] [Related]

  • 3. Reducing hepatic endoplasmic reticulum stress ameliorates the impairment in insulin signaling induced by high levels of β-hydroxybutyrate in bovine hepatocytes.
    Lei L, Gao W, Loor JJ, Aboragah A, Fang Z, Du X, Zhang M, Song Y, Liu G, Li X.
    J Dairy Sci; 2021 Dec; 104(12):12845-12858. PubMed ID: 34538494
    [Abstract] [Full Text] [Related]

  • 4. Hepatic nuclear factor kappa B signaling pathway and NLR family pyrin domain containing 3 inflammasome is over-activated in ketotic dairy cows.
    Shen T, Li X, Loor JJ, Zhu Y, Du X, Wang X, Xing D, Shi Z, Fang Z, Li X, Liu G.
    J Dairy Sci; 2019 Nov; 102(11):10554-10563. PubMed ID: 31495623
    [Abstract] [Full Text] [Related]

  • 5. Disruption of endoplasmic reticulum homeostasis exacerbates liver injury in clinically ketotic cows.
    Shi Z, Song Y, Gao X, Loor JJ, Aboragah A, Yu H, Fang Z, Zhu Y, Du X, Li X, Gao W, Liu G.
    J Dairy Sci; 2021 Aug; 104(8):9130-9141. PubMed ID: 34001360
    [Abstract] [Full Text] [Related]

  • 6. Nuciferine protects bovine hepatocytes against free fatty acid-induced oxidative damage by activating the transcription factor EB/peroxisome proliferator-activated receptor γ coactivator 1 alpha pathway.
    Fang Z, Jiang X, Wang S, Tai W, Jiang Q, Loor JJ, Yu H, Hao X, Chen M, Shao Q, Song Y, Lei L, Liu G, Du X, Li X.
    J Dairy Sci; 2024 Jan; 107(1):625-640. PubMed ID: 37709032
    [Abstract] [Full Text] [Related]

  • 7. Activated autophagy-lysosomal pathway in dairy cows with hyperketonemia is associated with lipolysis of adipose tissues.
    Yu H, Fan M, Chen X, Jiang X, Loor JJ, Aboragah A, Zhang C, Bai H, Fang Z, Shen T, Wang Z, Song Y, Li X, Liu G, Li X, Du X.
    J Dairy Sci; 2022 Aug; 105(8):6997-7010. PubMed ID: 35688731
    [Abstract] [Full Text] [Related]

  • 8. Impaired autophagy aggravates oxidative stress in mammary gland of dairy cows with clinical ketosis.
    Yue K, Pu X, Loor JJ, Jiang Q, Dong J, Shen T, Li G, Gao W, Lei L, Du X, Song Y, Liu G, Li X.
    J Dairy Sci; 2022 Jul; 105(7):6030-6040. PubMed ID: 35637003
    [Abstract] [Full Text] [Related]

  • 9. High concentrations of fatty acids and β-hydroxybutyrate impair the growth hormone-mediated hepatic JAK2-STAT5 pathway in clinically ketotic cows.
    Du X, Zhu Y, Peng Z, Cui Y, Zhang Q, Shi Z, Guan Y, Sha X, Shen T, Yang Y, Li X, Wang Z, Li X, Liu G.
    J Dairy Sci; 2018 Apr; 101(4):3476-3487. PubMed ID: 29398030
    [Abstract] [Full Text] [Related]

  • 10. Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis.
    Wang S, Ni HM, Chao X, Wang H, Bridges B, Kumer S, Schmitt T, Mareninova O, Gukovskaya A, De Lisle RC, Ballabio A, Pacher P, Ding WX.
    Autophagy; 2019 Nov; 15(11):1954-1969. PubMed ID: 30894069
    [Abstract] [Full Text] [Related]

  • 11. Enhanced mitochondrial dysfunction and oxidative stress in the mammary gland of cows with clinical ketosis.
    Song Y, Loor JJ, Li C, Liang Y, Li N, Shu X, Yang Y, Feng X, Du X, Wang Z, Liu G, Li X.
    J Dairy Sci; 2021 Jun; 104(6):6909-6918. PubMed ID: 33715853
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of cluster antigen 36 protects against fatty acid-induced lipid accumulation, oxidative stress, and inflammation in bovine hepatocytes.
    Zhao C, Li J, Liu M, Chen L, Zhu Y, Gao W, Du X, Song Y, Liu G, Lei L, Li X.
    J Dairy Sci; 2023 Dec; 106(12):9186-9199. PubMed ID: 37641277
    [Abstract] [Full Text] [Related]

  • 13. Fatty acids promote M1 polarization of monocyte-derived macrophages in healthy or ketotic dairy cows and a bovine macrophage cell line by impairing mTOR-mediated autophagy.
    Sun X, Gao S, Chang R, Jia H, Xu Q, Mauck J, Loor JJ, Li X, Xu C.
    J Dairy Sci; 2024 Sep; 107(9):7423-7434. PubMed ID: 38754818
    [Abstract] [Full Text] [Related]

  • 14. Role of sortilin 1 (SORT1) on fatty acid-mediated cholesterol metabolism in primary calf hepatocytes.
    Wang S, Jiang Q, Loor JJ, Gao C, Yang M, Tian Y, Fan W, Zhang B, Li M, Xu C, Yang W.
    J Dairy Sci; 2022 Sep; 105(9):7773-7786. PubMed ID: 35940922
    [Abstract] [Full Text] [Related]

  • 15. Hepatic autophagy and mitophagy status in dairy cows with subclinical and clinical ketosis.
    Shen T, Xu F, Fang Z, Loor JJ, Ouyang H, Chen M, Jin B, Wang X, Shi Z, Zhu Y, Liang Y, Ju L, Song Y, Wang Z, Li X, Du X, Liu G.
    J Dairy Sci; 2021 Apr; 104(4):4847-4857. PubMed ID: 33551163
    [Abstract] [Full Text] [Related]

  • 16. Low abundance of mitophagy markers is associated with reactive oxygen species overproduction in cows with fatty liver and causes reactive oxygen species overproduction and lipid accumulation in calf hepatocytes.
    Fang Z, Liu G, Zhu M, Wang S, Jiang Q, Loor JJ, Yu H, Hao X, Chen M, Gao W, Lei L, Song Y, Wang Z, Du X, Li X.
    J Dairy Sci; 2022 Sep; 105(9):7829-7841. PubMed ID: 35863923
    [Abstract] [Full Text] [Related]

  • 17. Regulation of Akt-mTOR, ubiquitin-proteasome and autophagy-lysosome pathways in response to formoterol administration in rat skeletal muscle.
    Joassard OR, Amirouche A, Gallot YS, Desgeorges MM, Castells J, Durieux AC, Berthon P, Freyssenet DG.
    Int J Biochem Cell Biol; 2013 Nov; 45(11):2444-55. PubMed ID: 23916784
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of cell death inducing DNA fragmentation factor-α-like effector c (CIDEC) by tumor necrosis factor-α induces lipolysis and inflammation in calf adipocytes.
    Fan M, Du X, Chen X, Bai H, Loor JJ, Shen T, Liang Y, Sun X, Xu Q, Song Y, Wang Z, Liu G, Yang L, Li X, Li X, Gao W.
    J Dairy Sci; 2021 May; 104(5):6134-6145. PubMed ID: 33685683
    [Abstract] [Full Text] [Related]

  • 19. AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE3.
    Paquette M, El-Houjeiri L, C Zirden L, Puustinen P, Blanchette P, Jeong H, Dejgaard K, Siegel PM, Pause A.
    Autophagy; 2021 Dec; 17(12):3957-3975. PubMed ID: 33734022
    [Abstract] [Full Text] [Related]

  • 20. Effects of diacylglycerol O-acyltransferase 1 (DGAT1) on endoplasmic reticulum stress and inflammatory responses in adipose tissue of ketotic dairy cows.
    Xu Q, Fan Y, Loor JJ, Jiang Q, Zheng X, Wang Z, Yang T, Sun X, Jia H, Li X, Xu C.
    J Dairy Sci; 2022 Nov; 105(11):9191-9205. PubMed ID: 36114053
    [Abstract] [Full Text] [Related]

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