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165 related items for PubMed ID: 3536143

  • 1. Expression in mammalian cells of a truncated Escherichia coli gene coding for O6-alkylguanine alkyltransferase reduces the toxic effects of alkylating agents.
    Brennand J, Margison GP.
    Carcinogenesis; 1986 Dec; 7(12):2081-4. PubMed ID: 3536143
    [Abstract] [Full Text] [Related]

  • 2. Reduction of the toxicity and mutagenicity of alkylating agents in mammalian cells harboring the Escherichia coli alkyltransferase gene.
    Brennand J, Margison GP.
    Proc Natl Acad Sci U S A; 1986 Sep; 83(17):6292-6. PubMed ID: 3529080
    [Abstract] [Full Text] [Related]

  • 3. Expression in mammalian cells of the Escherichia coli O6 alkylguanine-DNA-alkyltransferase gene ogt reduces the toxicity of alkylnitrosoureas.
    Harris LC, Margison GP.
    Br J Cancer; 1993 Jun; 67(6):1196-202. PubMed ID: 8512805
    [Abstract] [Full Text] [Related]

  • 4. Expression of an E.coli O6-alkylguanine DNA alkyltransferase gene in Chinese hamster cells protects against N-methyl and N-ethylnitrosourea induced reverse mutation at the hypoxanthine phosphoribosyl transferase locus.
    Fox M, Margison GP.
    Mutagenesis; 1988 Sep; 3(5):409-13. PubMed ID: 3070275
    [Abstract] [Full Text] [Related]

  • 5. Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents.
    Kaina B, Fritz G, Mitra S, Coquerelle T.
    Carcinogenesis; 1991 Oct; 12(10):1857-67. PubMed ID: 1657427
    [Abstract] [Full Text] [Related]

  • 6. Chinese hamster cells harbouring the Escherichia coli O6-alkylguanine alkyltransferase gene are less susceptible to sister chromatid exchange induction and chromosome damage by methylating agents.
    White GR, Ockey CH, Brennand J, Margison GP.
    Carcinogenesis; 1986 Dec; 7(12):2077-80. PubMed ID: 3536142
    [Abstract] [Full Text] [Related]

  • 7. Protection of Chinese hamster cells against the cytotoxic and mutagenic effects of alkylating agents by transfection of the Escherichia coli alkyltransferase gene and a truncated derivative.
    Fox M, Brennand J, Margison GP.
    Mutagenesis; 1987 Nov; 2(6):491-6. PubMed ID: 3328039
    [Abstract] [Full Text] [Related]

  • 8. Mammalian O6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents.
    Pegg AE.
    Cancer Res; 1990 Oct 01; 50(19):6119-29. PubMed ID: 2205376
    [No Abstract] [Full Text] [Related]

  • 9. Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents.
    Dolan ME, Norbeck L, Clyde C, Hora NK, Erickson LC, Pegg AE.
    Carcinogenesis; 1989 Sep 01; 10(9):1613-9. PubMed ID: 2766456
    [Abstract] [Full Text] [Related]

  • 10. Transfection of murine multi-potent haemopoietic stem cells with an E. coli DNA alkyltransferase gene confers resistance to the toxic effects of alkylating agents.
    Jelinek J, Kleibl K, Dexter TM, Margison GP.
    Carcinogenesis; 1988 Jan 01; 9(1):81-7. PubMed ID: 2826035
    [Abstract] [Full Text] [Related]

  • 11. Increased resistance to the toxic effects of alkylating agents in tobacco expressing the E. coli DNA repair gene ada.
    Angelis K, Bríza J, Satava J, Skákal I, Velemínský J, Vlasák J, Kleibl K, Margison GP.
    Mutat Res; 1992 May 01; 273(3):271-80. PubMed ID: 1374848
    [Abstract] [Full Text] [Related]

  • 12. Mammalian cells expressing Escherichia coli O6-alkylguanine-DNA alkyltransferases are hypersensitive to dibromoalkanes.
    Abril N, Margison GP.
    Chem Res Toxicol; 1999 Jun 01; 12(6):544-51. PubMed ID: 10368318
    [Abstract] [Full Text] [Related]

  • 13. O6-Alkylguanine-DNA alkyltransferase: influence on susceptibility to the genetic effects of alkylating agents.
    Kyrtopoulos SA.
    Toxicol Lett; 1998 Dec 28; 102-103():53-7. PubMed ID: 10022232
    [Abstract] [Full Text] [Related]

  • 14. The role of O6-alkylguanine in cell killing and mutagenesis in Chinese hamster ovary cells.
    Dunn WC, Tano K, Horesovsky GJ, Preston RJ, Mitra S.
    Carcinogenesis; 1991 Jan 28; 12(1):83-9. PubMed ID: 1988186
    [Abstract] [Full Text] [Related]

  • 15. Expression of the E. coli O6-methylguanine-methylphosphotriester methyltransferase gene in mammalian cells.
    Brennand J, Margison GP.
    Carcinogenesis; 1986 Jan 28; 7(1):185-8. PubMed ID: 3002654
    [Abstract] [Full Text] [Related]

  • 16. Site-specific mutagenesis by O6-alkylguanines located in the chromosomes of mammalian cells: influence of the mammalian O6-alkylguanine-DNA alkyltransferase.
    Ellison KS, Dogliotti E, Connors TD, Basu AK, Essigmann JM.
    Proc Natl Acad Sci U S A; 1989 Nov 28; 86(22):8620-4. PubMed ID: 2813414
    [Abstract] [Full Text] [Related]

  • 17. Purification of the E. coli ogt gene product to homogeneity and its rate of action on O6-methylguanine, O6-ethylguanine and O4-methylthymine in dodecadeoxyribonucleotides.
    Wilkinson MC, Potter PM, Cawkwell L, Georgiadis P, Patel D, Swann PF, Margison GP.
    Nucleic Acids Res; 1989 Nov 11; 17(21):8475-84. PubMed ID: 2685744
    [Abstract] [Full Text] [Related]

  • 18. Mutagenesis and DNA repair for alkylation damages in Escherichia coli K-12.
    Abril N, Roldán-Arjona T, Prieto-Alamo MJ, van Zeeland AA, Pueyo C.
    Environ Mol Mutagen; 1992 Nov 11; 19(4):288-96. PubMed ID: 1600955
    [Abstract] [Full Text] [Related]

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