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Journal Abstract Search
209 related items for PubMed ID: 35505609
1. Toxic SOD1 trimers are off-pathway in the formation of amyloid-like fibrils in ALS. Hnath B, Dokholyan NV. Biophys J; 2022 Jun 07; 121(11):2084-2095. PubMed ID: 35505609 [Abstract] [Full Text] [Related]
7. A hyperthermophilic protein G variant engineered via directed evolution prevents the formation of toxic SOD1 oligomers. Dagan B, Oren O, Banerjee V, Taube R, Papo N. Proteins; 2019 Sep 15; 87(9):738-747. PubMed ID: 31017342 [Abstract] [Full Text] [Related]
8. The Disulfide Bond, but Not Zinc or Dimerization, Controls Initiation and Seeded Growth in Amyotrophic Lateral Sclerosis-linked Cu,Zn Superoxide Dismutase (SOD1) Fibrillation. Chattopadhyay M, Nwadibia E, Strong CD, Gralla EB, Valentine JS, Whitelegge JP. J Biol Chem; 2015 Dec 18; 290(51):30624-36. PubMed ID: 26511321 [Abstract] [Full Text] [Related]
9. Non-native soluble oligomers of Cu/Zn superoxide dismutase (SOD1) contain a conformational epitope linked to cytotoxicity in amyotrophic lateral sclerosis (ALS). Redler RL, Fee L, Fay JM, Caplow M, Dokholyan NV. Biochemistry; 2014 Apr 15; 53(14):2423-32. PubMed ID: 24660965 [Abstract] [Full Text] [Related]
10. Structural similarity of wild-type and ALS-mutant superoxide dismutase-1 fibrils using limited proteolysis and atomic force microscopy. Chan PK, Chattopadhyay M, Sharma S, Souda P, Gralla EB, Borchelt DR, Whitelegge JP, Valentine JS. Proc Natl Acad Sci U S A; 2013 Jul 02; 110(27):10934-9. PubMed ID: 23781106 [Abstract] [Full Text] [Related]
16. Nonnative SOD1 trimer is toxic to motor neurons in a model of amyotrophic lateral sclerosis. Proctor EA, Fee L, Tao Y, Redler RL, Fay JM, Zhang Y, Lv Z, Mercer IP, Deshmukh M, Lyubchenko YL, Dokholyan NV. Proc Natl Acad Sci U S A; 2016 Jan 19; 113(3):614-9. PubMed ID: 26719414 [Abstract] [Full Text] [Related]
17. Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice. Hadano S, Mitsui S, Pan L, Otomo A, Kubo M, Sato K, Ono S, Onodera W, Abe K, Chen X, Koike M, Uchiyama Y, Aoki M, Warabi E, Yamamoto M, Ishii T, Yanagawa T, Shang HF, Yoshii F. Hum Mol Genet; 2016 Aug 01; 25(15):3321-3340. PubMed ID: 27439389 [Abstract] [Full Text] [Related]
18. Disruption of mitochondrial membrane integrity induced by amyloid aggregates arising from variants of SOD1. Oladzad Abbasabadi A, Javanian A, Nikkhah M, Meratan AA, Ghiasi P, Nemat-Gorgani M. Int J Biol Macromol; 2013 Oct 01; 61():212-7. PubMed ID: 23872456 [Abstract] [Full Text] [Related]