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167 related items for PubMed ID: 35524054

  • 1. Heterologous Expression, Purification, and Characterization of Type II Polyketide Synthase Acyl Carrier Proteins.
    Hamrick GS, Londergan CH, Charkoudian LK.
    Methods Mol Biol; 2022; 2489():239-267. PubMed ID: 35524054
    [Abstract] [Full Text] [Related]

  • 2. Probing the structure and function of acyl carrier proteins to unlock the strategic redesign of type II polyketide biosynthetic pathways.
    Sulpizio A, Crawford CEW, Koweek RS, Charkoudian LK.
    J Biol Chem; 2021; 296():100328. PubMed ID: 33493513
    [Abstract] [Full Text] [Related]

  • 3. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
    Tang Y, Lee TS, Kobayashi S, Khosla C.
    Biochemistry; 2003 Jun 03; 42(21):6588-95. PubMed ID: 12767243
    [Abstract] [Full Text] [Related]

  • 4. Structure, function and dynamics in acyl carrier proteins.
    Farmer R, Thomas CM, Winn PJ.
    PLoS One; 2019 Jun 03; 14(7):e0219435. PubMed ID: 31291335
    [Abstract] [Full Text] [Related]

  • 5. Engineered Chimeras Unveil Swappable Modular Features of Fatty Acid and Polyketide Synthase Acyl Carrier Proteins.
    Cho YI, Armstrong CL, Sulpizio A, Acheampong KK, Banks KN, Bardhan O, Churchill SJ, Connolly-Sporing AE, Crawford CEW, Cruz Parrilla PL, Curtis SM, De La Ossa LM, Epstein SC, Farrehi CJ, Hamrick GS, Hillegas WJ, Kang A, Laxton OC, Ling J, Matsumura SM, Merino VM, Mukhtar SH, Shah NJ, Londergan CH, Daly CA, Kokona B, Charkoudian LK.
    Biochemistry; 2022 Feb 15; 61(4):217-227. PubMed ID: 35073057
    [Abstract] [Full Text] [Related]

  • 6. How Acyl Carrier Proteins (ACPs) Direct Fatty Acid and Polyketide Biosynthesis.
    Buyachuihan L, Stegemann F, Grininger M.
    Angew Chem Int Ed Engl; 2024 Jan 22; 63(4):e202312476. PubMed ID: 37856285
    [Abstract] [Full Text] [Related]

  • 7. The malonyl transferase activity of type II polyketide synthase acyl carrier proteins.
    Arthur CJ, Szafranska AE, Long J, Mills J, Cox RJ, Findlow SC, Simpson TJ, Crump MP, Crosby J.
    Chem Biol; 2006 Jun 22; 13(6):587-96. PubMed ID: 16793516
    [Abstract] [Full Text] [Related]

  • 8. Utilization of enzymatically phosphopantetheinylated acyl carrier proteins and acetyl-acyl carrier proteins by the actinorhodin polyketide synthase.
    Carreras CW, Gehring AM, Walsh CT, Khosla C.
    Biochemistry; 1997 Sep 30; 36(39):11757-61. PubMed ID: 9305965
    [Abstract] [Full Text] [Related]

  • 9. Offloading Role of a Discrete Thioesterase in Type II Polyketide Biosynthesis.
    Hua K, Liu X, Zhao Y, Gao Y, Pan L, Zhang H, Deng Z, Jiang M.
    mBio; 2020 Sep 15; 11(5):. PubMed ID: 32934080
    [Abstract] [Full Text] [Related]

  • 10. Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor.
    Chemler JA, Buchholz TJ, Geders TW, Akey DL, Rath CM, Chlipala GE, Smith JL, Sherman DH.
    J Am Chem Soc; 2012 May 02; 134(17):7359-66. PubMed ID: 22480290
    [Abstract] [Full Text] [Related]

  • 11. Heterologously expressed acyl carrier protein domain of rat fatty acid synthase functions in Escherichia coli fatty acid synthase and Streptomyces coelicolor polyketide synthase systems.
    Tropf S, Revill WP, Bibb MJ, Hopwood DA, Schweizer M.
    Chem Biol; 1998 Mar 02; 5(3):135-46. PubMed ID: 9545424
    [Abstract] [Full Text] [Related]

  • 12. Widening the bottleneck: Heterologous expression, purification, and characterization of the Ktedonobacter racemifer minimal type II polyketide synthase in Escherichia coli.
    Klein JG, Wu Y, Kokona B, Charkoudian LK.
    Bioorg Med Chem; 2020 Oct 15; 28(20):115686. PubMed ID: 33069071
    [Abstract] [Full Text] [Related]

  • 13. Self-malonylation is an intrinsic property of a chemically synthesized type II polyketide synthase acyl carrier protein.
    Arthur CJ, Szafranska A, Evans SE, Findlow SC, Burston SG, Owen P, Clark-Lewis I, Simpson TJ, Crosby J, Crump MP.
    Biochemistry; 2005 Nov 22; 44(46):15414-21. PubMed ID: 16285746
    [Abstract] [Full Text] [Related]

  • 14. De Novo Design and Implementation of a Tandem Acyl Carrier Protein Domain in a Type I Modular Polyketide Synthase.
    Wang Z, Bagde SR, Zavala G, Matsui T, Chen X, Kim CY.
    ACS Chem Biol; 2018 Nov 16; 13(11):3072-3077. PubMed ID: 30354045
    [Abstract] [Full Text] [Related]

  • 15. Structural basis for selectivity in a highly reducing type II polyketide synthase.
    Du D, Katsuyama Y, Horiuchi M, Fushinobu S, Chen A, Davis TD, Burkart MD, Ohnishi Y.
    Nat Chem Biol; 2020 Jul 16; 16(7):776-782. PubMed ID: 32367018
    [Abstract] [Full Text] [Related]

  • 16. Type I polyketide synthases that require discrete acyltransferases.
    Cheng YQ, Coughlin JM, Lim SK, Shen B.
    Methods Enzymol; 2009 Jul 16; 459():165-86. PubMed ID: 19362640
    [Abstract] [Full Text] [Related]

  • 17. Prediction of inter domain interactions in modular polyketide synthases by docking and correlated mutation analysis.
    Yadav G, Anand S, Mohanty D.
    J Biomol Struct Dyn; 2013 Jul 16; 31(1):17-29. PubMed ID: 22803697
    [Abstract] [Full Text] [Related]

  • 18. Heterologous expression, purification, reconstitution and kinetic analysis of an extended type II polyketide synthase.
    Zawada RJ, Khosla C.
    Chem Biol; 1999 Sep 16; 6(9):607-15. PubMed ID: 10467128
    [Abstract] [Full Text] [Related]

  • 19. In vivo and in vitro analysis of the hedamycin polyketide synthase.
    Das A, Khosla C.
    Chem Biol; 2009 Nov 25; 16(11):1197-207. PubMed ID: 19942143
    [Abstract] [Full Text] [Related]

  • 20. Probing the Interactions of early polyketide intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
    Evans SE, Williams C, Arthur CJ, Płoskoń E, Wattana-amorn P, Cox RJ, Crosby J, Willis CL, Simpson TJ, Crump MP.
    J Mol Biol; 2009 Jun 12; 389(3):511-28. PubMed ID: 19361520
    [Abstract] [Full Text] [Related]

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