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219 related items for PubMed ID: 35525199

  • 1. Engineering a U-box of E3 ligase E4B through yeast surface display-based functional screening generates a variant with enhanced ubiquitin ligase activity.
    Park SW, Lee DS, Kim YS.
    Biochem Biophys Res Commun; 2022 Jul 05; 612():147-153. PubMed ID: 35525199
    [Abstract] [Full Text] [Related]

  • 2. Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer.
    Bhuripanyo K, Wang Y, Liu X, Zhou L, Liu R, Duong D, Zhao B, Bi Y, Zhou H, Chen G, Seyfried NT, Chazin WJ, Kiyokawa H, Yin J.
    Sci Adv; 2018 Jan 05; 4(1):e1701393. PubMed ID: 29326975
    [Abstract] [Full Text] [Related]

  • 3. Structural insights into non-covalent ubiquitin activation of the cIAP1-UbcH5B∼ubiquitin complex.
    Patel A, Sibbet GJ, Huang DT.
    J Biol Chem; 2019 Jan 25; 294(4):1240-1249. PubMed ID: 30523153
    [Abstract] [Full Text] [Related]

  • 4. Classification and interaction modes of 40 rice E2 ubiquitin-conjugating enzymes with 17 rice ARM-U-box E3 ubiquitin ligases.
    Bae H, Kim WT.
    Biochem Biophys Res Commun; 2014 Feb 21; 444(4):575-80. PubMed ID: 24486490
    [Abstract] [Full Text] [Related]

  • 5. Recruitment of ubiquitin E2 enzymes is determined jointly by the U-box domains and substrates of E3 ligases.
    Jin B, Li B, Qu J, Sun Y, Wang M, Yang C, Fan Y, Wang Y, Xu P, Sun H, Jiang B, Zhao B.
    FEBS Lett; 2024 Mar 21; 598(6):702-715. PubMed ID: 38439679
    [Abstract] [Full Text] [Related]

  • 6. Dual-color pulse-chase ubiquitination assays to simultaneously monitor substrate priming and extension.
    Scott DC, Schulman BA.
    Methods Enzymol; 2019 Mar 21; 618():29-48. PubMed ID: 30850057
    [Abstract] [Full Text] [Related]

  • 7. Identification and Characterization of Physiological Pairing of E2 Ubiquitin-Conjugating Enzymes and E3 Ubiquitin Ligases.
    Brillada C, Trujillo M.
    Methods Mol Biol; 2023 Mar 21; 2581():13-29. PubMed ID: 36413307
    [Abstract] [Full Text] [Related]

  • 8. Activation of UbcH5c~Ub is the result of a shift in interdomain motions of the conjugate bound to U-box E3 ligase E4B.
    Soss SE, Klevit RE, Chazin WJ.
    Biochemistry; 2013 Apr 30; 52(17):2991-9. PubMed ID: 23550736
    [Abstract] [Full Text] [Related]

  • 9. Molecular basis for lysine specificity in the yeast ubiquitin-conjugating enzyme Cdc34.
    Sadowski M, Suryadinata R, Lai X, Heierhorst J, Sarcevic B.
    Mol Cell Biol; 2010 May 30; 30(10):2316-29. PubMed ID: 20194622
    [Abstract] [Full Text] [Related]

  • 10. Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.
    Pruneda JN, Littlefield PJ, Soss SE, Nordquist KA, Chazin WJ, Brzovic PS, Klevit RE.
    Mol Cell; 2012 Sep 28; 47(6):933-42. PubMed ID: 22885007
    [Abstract] [Full Text] [Related]

  • 11. Assays for dissecting the in vitro enzymatic activity of yeast Ubc7.
    Mashahreh B, Reiss Y, Wiener R, Ravid T.
    Methods Enzymol; 2019 Sep 28; 619():71-95. PubMed ID: 30910030
    [Abstract] [Full Text] [Related]

  • 12. Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.
    Kim HT, Kim KP, Lledias F, Kisselev AF, Scaglione KM, Skowyra D, Gygi SP, Goldberg AL.
    J Biol Chem; 2007 Jun 15; 282(24):17375-86. PubMed ID: 17426036
    [Abstract] [Full Text] [Related]

  • 13. Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.
    Pao KC, Wood NT, Knebel A, Rafie K, Stanley M, Mabbitt PD, Sundaramoorthy R, Hofmann K, van Aalten DMF, Virdee S.
    Nature; 2018 Apr 15; 556(7701):381-385. PubMed ID: 29643511
    [Abstract] [Full Text] [Related]

  • 14. Activation of a primed RING E3-E2-ubiquitin complex by non-covalent ubiquitin.
    Buetow L, Gabrielsen M, Anthony NG, Dou H, Patel A, Aitkenhead H, Sibbet GJ, Smith BO, Huang DT.
    Mol Cell; 2015 Apr 16; 58(2):297-310. PubMed ID: 25801170
    [Abstract] [Full Text] [Related]

  • 15. Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms.
    Dove KK, Stieglitz B, Duncan ED, Rittinger K, Klevit RE.
    EMBO Rep; 2016 Aug 16; 17(8):1221-35. PubMed ID: 27312108
    [Abstract] [Full Text] [Related]

  • 16. Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis.
    Starita LM, Pruneda JN, Lo RS, Fowler DM, Kim HJ, Hiatt JB, Shendure J, Brzovic PS, Fields S, Klevit RE.
    Proc Natl Acad Sci U S A; 2013 Apr 02; 110(14):E1263-72. PubMed ID: 23509263
    [Abstract] [Full Text] [Related]

  • 17. Insights into ubiquitin transfer cascades from a structure of a UbcH5B approximately ubiquitin-HECT(NEDD4L) complex.
    Kamadurai HB, Souphron J, Scott DC, Duda DM, Miller DJ, Stringer D, Piper RC, Schulman BA.
    Mol Cell; 2009 Dec 25; 36(6):1095-102. PubMed ID: 20064473
    [Abstract] [Full Text] [Related]

  • 18. Structural and functional characterization of the monomeric U-box domain from E4B.
    Nordquist KA, Dimitrova YN, Brzovic PS, Ridenour WB, Munro KA, Soss SE, Caprioli RM, Klevit RE, Chazin WJ.
    Biochemistry; 2010 Jan 19; 49(2):347-55. PubMed ID: 20017557
    [Abstract] [Full Text] [Related]

  • 19. The essential Ubc4/Ubc5 function in yeast is HECT E3-dependent, and RING E3-dependent pathways require only monoubiquitin transfer by Ubc4.
    Stoll KE, Brzovic PS, Davis TN, Klevit RE.
    J Biol Chem; 2011 Apr 29; 286(17):15165-70. PubMed ID: 21357418
    [Abstract] [Full Text] [Related]

  • 20. BIRC7-E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer.
    Dou H, Buetow L, Sibbet GJ, Cameron K, Huang DT.
    Nat Struct Mol Biol; 2012 Sep 29; 19(9):876-83. PubMed ID: 22902369
    [Abstract] [Full Text] [Related]

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