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Journal Abstract Search

166 related items for PubMed ID: 35563116

  • 1. Stereoselective Covalent Adduct Formation of Acyl Glucuronide Metabolite of Nonsteroidal Anti-Inflammatory Drugs with UDP-Glucuronosyltransferase.
    Kawase A, Yamashita R, Yoshizato T, Yoshikawa M, Shimada H, Iwaki M.
    Int J Mol Sci; 2022 Apr 25; 23(9):. PubMed ID: 35563116
    [Abstract] [Full Text] [Related]

  • 2. Correlation between glucuronidation and covalent adducts formation with proteins of nonsteroidal anti-inflammatory drugs.
    Shimada H, Kobayashi Y, Tanahashi S, Kawase A, Ogiso T, Iwaki M.
    Eur J Pharm Sci; 2018 Jan 15; 112():132-138. PubMed ID: 29174986
    [Abstract] [Full Text] [Related]

  • 3. Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver.
    Mano Y, Usui T, Kamimura H.
    Drug Metab Dispos; 2007 Jul 15; 35(7):1182-7. PubMed ID: 17446261
    [Abstract] [Full Text] [Related]

  • 4. Stereoselective glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin by human UDP-glucuronosyltransferase (UGT) 1A1, UGT1A9, and UGT2B15: effects of UGT-UGT interactions.
    Nakajima M, Yamanaka H, Fujiwara R, Katoh M, Yokoi T.
    Drug Metab Dispos; 2007 Sep 15; 35(9):1679-86. PubMed ID: 17576806
    [Abstract] [Full Text] [Related]

  • 5. Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
    Koga T, Fujiwara R, Nakajima M, Yokoi T.
    Drug Metab Dispos; 2011 Jan 15; 39(1):54-60. PubMed ID: 20926620
    [Abstract] [Full Text] [Related]

  • 6. Inhibitory potential of nonsteroidal anti-inflammatory drugs on UDP-glucuronosyltransferase 2B7 in human liver microsomes.
    Mano Y, Usui T, Kamimura H.
    Eur J Clin Pharmacol; 2007 Feb 15; 63(2):211-6. PubMed ID: 17200831
    [Abstract] [Full Text] [Related]

  • 7. Cysteine amide adduct formation from carboxylic acid drugs via UGT-mediated bioactivation in human liver microsomes.
    Harada H, Toyoda Y, Endo T, Kobayashi M.
    Pharmazie; 2015 Oct 15; 70(10):678-83. PubMed ID: 26601426
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of 20-hydroxyeicosatetraenoic acid (20-HETE) glucuronidation by non-steroidal anti-inflammatory drugs in human liver microsomes and recombinant UDP-glucuronosyltransferase enzymes.
    Jarrar YB, Kim DH, Lee SJ, Shin JG.
    Prostaglandins Leukot Essent Fatty Acids; 2020 Feb 15; 153():102055. PubMed ID: 31999978
    [Abstract] [Full Text] [Related]

  • 9. Glucuronidation of fenamates: kinetic studies using human kidney cortical microsomes and recombinant UDP-glucuronosyltransferase (UGT) 1A9 and 2B7.
    Gaganis P, Miners JO, Knights KM.
    Biochem Pharmacol; 2007 May 15; 73(10):1683-91. PubMed ID: 17343829
    [Abstract] [Full Text] [Related]

  • 10. Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform.
    Kaji H, Kume T.
    Drug Metab Dispos; 2005 Mar 15; 33(3):403-12. PubMed ID: 15608137
    [Abstract] [Full Text] [Related]

  • 11. Characterizing the effect of UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A9 genetic polymorphisms on enantioselective glucuronidation of flurbiprofen.
    Wang H, Yuan L, Zeng S.
    Biochem Pharmacol; 2011 Dec 01; 82(11):1757-63. PubMed ID: 21856293
    [Abstract] [Full Text] [Related]

  • 12. Stereoselective glucuronidation of propranolol in human and cynomolgus monkey liver microsomes: role of human hepatic UDP-glucuronosyltransferase isoforms, UGT1A9, UGT2B4 and UGT2B7.
    Hanioka N, Hayashi K, Shimizudani T, Nagaoka K, Koeda A, Naito S, Narimatsu S.
    Pharmacology; 2008 Dec 01; 82(4):293-303. PubMed ID: 18936551
    [Abstract] [Full Text] [Related]

  • 13. Aldosterone glucuronidation by human liver and kidney microsomes and recombinant UDP-glucuronosyltransferases: inhibition by NSAIDs.
    Knights KM, Winner LK, Elliot DJ, Bowalgaha K, Miners JO.
    Br J Clin Pharmacol; 2009 Sep 01; 68(3):402-12. PubMed ID: 19740398
    [Abstract] [Full Text] [Related]

  • 14. UDP-glucuronosyltransferase (UGT) 1A1 mainly contributes to the glucuronidation of trovafloxacin.
    Fujiwara R, Sumida K, Kutsuno Y, Sakamoto M, Itoh T.
    Drug Metab Pharmacokinet; 2015 Feb 01; 30(1):82-8. PubMed ID: 25760534
    [Abstract] [Full Text] [Related]

  • 15. Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.
    Fujiwara R, Nakajima M, Yamanaka H, Katoh M, Yokoi T.
    Drug Metab Dispos; 2008 Feb 01; 36(2):361-7. PubMed ID: 17998297
    [Abstract] [Full Text] [Related]

  • 16. Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes.
    Kuehl GE, Lampe JW, Potter JD, Bigler J.
    Drug Metab Dispos; 2005 Jul 01; 33(7):1027-35. PubMed ID: 15843492
    [Abstract] [Full Text] [Related]

  • 17. Characterization of benzo(a)pyrene-trans-7,8-dihydrodiol glucuronidation by human tissue microsomes and overexpressed UDP-glucuronosyltransferase enzymes.
    Fang JL, Beland FA, Doerge DR, Wiener D, Guillemette C, Marques MM, Lazarus P.
    Cancer Res; 2002 Apr 01; 62(7):1978-86. PubMed ID: 11929814
    [Abstract] [Full Text] [Related]

  • 18. Human and rat liver UDP-glucuronosyltransferases are targets of ketoprofen acylglucuronide.
    Terrier N, Benoit E, Senay C, Lapicque F, Radominska-Pandya A, Magdalou J, Fournel-Gigleux S.
    Mol Pharmacol; 1999 Jul 01; 56(1):226-34. PubMed ID: 10385704
    [Abstract] [Full Text] [Related]

  • 19. Non-steroidal anti-inflammatory drugs interact with testosterone glucuronidation.
    Sten T, Finel M, Ask B, Rane A, Ekström L.
    Steroids; 2009 Nov 01; 74(12):971-7. PubMed ID: 19643121
    [Abstract] [Full Text] [Related]

  • 20. Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions .
    Kahma H, Filppula AM, Neuvonen M, Tarkiainen EK, Tornio A, Holmberg MT, Itkonen MK, Finel M, Neuvonen PJ, Niemi M, Backman JT.
    Drug Metab Dispos; 2018 Feb 01; 46(2):141-150. PubMed ID: 29138287
    [Abstract] [Full Text] [Related]

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