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211 related items for PubMed ID: 35752212

  • 1. Conformational Dynamics Allows Sampling of an "Active-like" State by Oncogenic K-Ras-GDP.
    Grudzien P, Jang H, Leschinsky N, Nussinov R, Gaponenko V.
    J Mol Biol; 2022 Sep 15; 434(17):167695. PubMed ID: 35752212
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  • 2. The Structural Basis of Oncogenic Mutations G12, G13 and Q61 in Small GTPase K-Ras4B.
    Lu S, Jang H, Nussinov R, Zhang J.
    Sci Rep; 2016 Feb 23; 6():21949. PubMed ID: 26902995
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  • 3. GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site.
    Lu S, Banerjee A, Jang H, Zhang J, Gaponenko V, Nussinov R.
    J Biol Chem; 2015 Nov 27; 290(48):28887-900. PubMed ID: 26453300
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  • 6. Distinct dynamics and interaction patterns in H- and K-Ras oncogenic P-loop mutants.
    Sayyed-Ahmad A, Prakash P, Gorfe AA.
    Proteins; 2017 Sep 27; 85(9):1618-1632. PubMed ID: 28498561
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  • 7. Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
    Xu S, Long BN, Boris GH, Chen A, Ni S, Kennedy MA.
    Acta Crystallogr D Struct Biol; 2017 Dec 01; 73(Pt 12):970-984. PubMed ID: 29199977
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  • 8. 1H, 15N backbone assignment and comparative analysis of the wild type and G12C, G12D, G12V mutants of K-Ras bound to GDP at physiological pH.
    Pálfy G, Vida I, Perczel A.
    Biomol NMR Assign; 2020 Apr 01; 14(1):1-7. PubMed ID: 31468366
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  • 9. An NMR comparison of the changes produced by different guanosine 5'-triphosphate analogs in wild-type and oncogenic mutant p21ras.
    Miller AF, Halkides CJ, Redfield AG.
    Biochemistry; 1993 Jul 27; 32(29):7367-76. PubMed ID: 8338834
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  • 10. NMR 1H, 13C, 15N backbone resonance assignments of wild-type human K-Ras and its oncogenic mutants G12D and G12C bound to GTP.
    Yuan C, Hansen AL, Bruschweiler-Li L, Brüschweiler R.
    Biomol NMR Assign; 2024 Jun 27; 18(1):7-13. PubMed ID: 37948018
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  • 11. Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site.
    Mazhab-Jafari MT, Marshall CB, Smith MJ, Gasmi-Seabrook GM, Stathopulos PB, Inagaki F, Kay LE, Neel BG, Ikura M.
    Proc Natl Acad Sci U S A; 2015 May 26; 112(21):6625-30. PubMed ID: 25941399
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  • 14. Oncogenic G12D mutation alters local conformations and dynamics of K-Ras.
    Vatansever S, Erman B, Gümüş ZH.
    Sci Rep; 2019 Aug 13; 9(1):11730. PubMed ID: 31409810
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  • 15. Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States.
    Gentile DR, Rathinaswamy MK, Jenkins ML, Moss SM, Siempelkamp BD, Renslo AR, Burke JE, Shokat KM.
    Cell Chem Biol; 2017 Dec 21; 24(12):1455-1466.e14. PubMed ID: 29033317
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  • 16. High-frequency 94 GHz ENDOR characterization of the metal binding site in wild-type Ras x GDP and its oncogenic mutant G12V in frozen solution.
    Bennati M, Hertel MM, Fritscher J, Prisner TF, Weiden N, Hofweber R, Spörner M, Horn G, Kalbitzer HR.
    Biochemistry; 2006 Jan 10; 45(1):42-50. PubMed ID: 16388579
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  • 17. K-Ras Populates Conformational States Differently from Its Isoform H-Ras and Oncogenic Mutant K-RasG12D.
    Parker JA, Volmar AY, Pavlopoulos S, Mattos C.
    Structure; 2018 Jun 05; 26(6):810-820.e4. PubMed ID: 29706533
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  • 18. Active and Inactive Cdc42 Differ in Their Insert Region Conformational Dynamics.
    Haspel N, Jang H, Nussinov R.
    Biophys J; 2021 Jan 19; 120(2):306-318. PubMed ID: 33347888
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