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232 related items for PubMed ID: 35794401

  • 1. KPNB1 modulates the Machado-Joseph disease protein ataxin-3 through activation of the mitochondrial protease CLPP.
    Abeditashi M, Weber JJ, Pereira Sena P, Velic A, Kalimeri M, Incebacak Eltemur RD, Schmidt J, Hübener-Schmid J, Hauser S, Macek B, Riess O, Schmidt T.
    Cell Mol Life Sci; 2022 Jul 06; 79(8):401. PubMed ID: 35794401
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  • 12. A new humanized ataxin-3 knock-in mouse model combines the genetic features, pathogenesis of neurons and glia and late disease onset of SCA3/MJD.
    Switonski PM, Szlachcic WJ, Krzyzosiak WJ, Figiel M.
    Neurobiol Dis; 2015 Jan 06; 73():174-88. PubMed ID: 25301414
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  • 14. Identification of the calpain-generated toxic fragment of ataxin-3 protein provides new avenues for therapy of Machado-Joseph disease| Spinocerebellar ataxia type 3.
    Simões AT, Carmona V, Duarte-Neves J, Cunha-Santos J, Pereira de Almeida L.
    Neuropathol Appl Neurobiol; 2022 Feb 06; 48(1):e12748. PubMed ID: 34273111
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  • 15. [Polyglutamine-expanded ataxin-3 is degraded by autophagy].
    Xiao H, Tang J, Hu Z, Tan J, Tang B, Jiang Z.
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2010 Feb 06; 27(1):23-8. PubMed ID: 20140862
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  • 16. The deubiquitinase function of ataxin-3 and its role in the pathogenesis of Machado-Joseph disease and other diseases.
    Potapenko A, Davidson JM, Lee A, Laird AS.
    Biochem J; 2024 Mar 20; 481(6):461-480. PubMed ID: 38497605
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  • 17. Karyopherin α-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3.
    Sowa AS, Martin E, Martins IM, Schmidt J, Depping R, Weber JJ, Rother F, Hartmann E, Bader M, Riess O, Tricoire H, Schmidt T.
    Proc Natl Acad Sci U S A; 2018 Mar 13; 115(11):E2624-E2633. PubMed ID: 29476013
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  • 18. A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration.
    Goti D, Katzen SM, Mez J, Kurtis N, Kiluk J, Ben-Haïem L, Jenkins NA, Copeland NG, Kakizuka A, Sharp AH, Ross CA, Mouton PR, Colomer V.
    J Neurosci; 2004 Nov 10; 24(45):10266-79. PubMed ID: 15537899
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  • 19. Ataxin-3 protein modification as a treatment strategy for spinocerebellar ataxia type 3: removal of the CAG containing exon.
    Evers MM, Tran HD, Zalachoras I, Pepers BA, Meijer OC, den Dunnen JT, van Ommen GJ, Aartsma-Rus A, van Roon-Mom WM.
    Neurobiol Dis; 2013 Oct 10; 58():49-56. PubMed ID: 23659897
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  • 20. Toward understanding Machado-Joseph disease.
    Costa Mdo C, Paulson HL.
    Prog Neurobiol; 2012 May 10; 97(2):239-57. PubMed ID: 22133674
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