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257 related items for PubMed ID: 35797482

  • 1. Genetic variation in HIF-2α attenuates ventilatory sensitivity and carotid body growth in chronic hypoxia in high-altitude deer mice.
    Ivy CM, Velotta JP, Cheviron ZA, Scott GR.
    J Physiol; 2022 Sep; 600(18):4207-4225. PubMed ID: 35797482
    [Abstract] [Full Text] [Related]

  • 2. Physiological and genomic evidence that selection on the transcription factor Epas1 has altered cardiovascular function in high-altitude deer mice.
    Schweizer RM, Velotta JP, Ivy CM, Jones MR, Muir SM, Bradburd GS, Storz JF, Scott GR, Cheviron ZA.
    PLoS Genet; 2019 Nov; 15(11):e1008420. PubMed ID: 31697676
    [Abstract] [Full Text] [Related]

  • 3. Control of breathing and ventilatory acclimatization to hypoxia in deer mice native to high altitudes.
    Ivy CM, Scott GR.
    Acta Physiol (Oxf); 2017 Dec; 221(4):266-282. PubMed ID: 28640969
    [Abstract] [Full Text] [Related]

  • 4. High-altitude deer mouse hypoxia-inducible factor-2α shows defective interaction with CREB-binding protein.
    Song D, Bigham AW, Lee FS.
    J Biol Chem; 2021 Dec; 296():100461. PubMed ID: 33639161
    [Abstract] [Full Text] [Related]

  • 5. Genetic variation in haemoglobin is associated with evolved changes in breathing in high-altitude deer mice.
    Ivy CM, Wearing OH, Natarajan C, Schweizer RM, Gutiérrez-Pinto N, Velotta JP, Campbell-Staton SC, Petersen EE, Fago A, Cheviron ZA, Storz JF, Scott GR.
    J Exp Biol; 2022 Jan 15; 225(2):. PubMed ID: 34913467
    [Abstract] [Full Text] [Related]

  • 6. Ontogenesis of evolved changes in respiratory physiology in deer mice native to high altitude.
    Ivy CM, Greaves MA, Sangster ED, Robertson CE, Natarajan C, Storz JF, McClelland GB, Scott GR.
    J Exp Biol; 2020 Mar 11; 223(Pt 5):. PubMed ID: 32054682
    [Abstract] [Full Text] [Related]

  • 7. Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia.
    Peng Y, Cui C, He Y, Ouzhuluobu, Zhang H, Yang D, Zhang Q, Bianbazhuoma, Yang L, He Y, Xiang K, Zhang X, Bhandari S, Shi P, Yangla, Dejiquzong, Baimakangzhuo, Duojizhuoma, Pan Y, Cirenyangji, Baimayangji, Gonggalanzi, Bai C, Bianba, Basang, Ciwangsangbu, Xu S, Chen H, Liu S, Wu T, Qi X, Su B.
    Mol Biol Evol; 2017 Apr 01; 34(4):818-830. PubMed ID: 28096303
    [Abstract] [Full Text] [Related]

  • 8. Evolved changes in breathing and CO2 sensitivity in deer mice native to high altitudes.
    Ivy CM, Scott GR.
    Am J Physiol Regul Integr Comp Physiol; 2018 Nov 01; 315(5):R1027-R1037. PubMed ID: 30183337
    [Abstract] [Full Text] [Related]

  • 9. The von Hippel-Lindau Chuvash mutation in mice causes carotid-body hyperplasia and enhanced ventilatory sensitivity to hypoxia.
    Slingo ME, Turner PJ, Christian HC, Buckler KJ, Robbins PA.
    J Appl Physiol (1985); 2014 Apr 01; 116(7):885-92. PubMed ID: 24030664
    [Abstract] [Full Text] [Related]

  • 10. Life-long exposure to hypoxia affects metabolism and respiratory physiology across life stages in high-altitude deer mice (Peromyscus maniculatus).
    Ivy CM, Scott GR.
    J Exp Biol; 2021 Jan 07; 224(Pt 1):. PubMed ID: 33268530
    [Abstract] [Full Text] [Related]

  • 11. Gain-of-function EGLN1 prolyl hydroxylase (PHD2 D4E:C127S) in combination with EPAS1 (HIF-2α) polymorphism lowers hemoglobin concentration in Tibetan highlanders.
    Tashi T, Scott Reading N, Wuren T, Zhang X, Moore LG, Hu H, Tang F, Shestakova A, Lorenzo F, Burjanivova T, Koul P, Guchhait P, Wittwer CT, Julian CG, Shah B, Huff CD, Gordeuk VR, Prchal JT, Ge R.
    J Mol Med (Berl); 2017 Jun 07; 95(6):665-670. PubMed ID: 28233034
    [Abstract] [Full Text] [Related]

  • 12. Control of breathing and the circulation in high-altitude mammals and birds.
    Ivy CM, Scott GR.
    Comp Biochem Physiol A Mol Integr Physiol; 2015 Aug 07; 186():66-74. PubMed ID: 25446936
    [Abstract] [Full Text] [Related]

  • 13. Evolved changes in the intracellular distribution and physiology of muscle mitochondria in high-altitude native deer mice.
    Mahalingam S, McClelland GB, Scott GR.
    J Physiol; 2017 Jul 15; 595(14):4785-4801. PubMed ID: 28418073
    [Abstract] [Full Text] [Related]

  • 14. Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway.
    Hodson EJ, Nicholls LG, Turner PJ, Llyr R, Fielding JW, Douglas G, Ratnayaka I, Robbins PA, Pugh CW, Buckler KJ, Ratcliffe PJ, Bishop T.
    J Physiol; 2016 Mar 01; 594(5):1179-95. PubMed ID: 26337139
    [Abstract] [Full Text] [Related]

  • 15. Tibetans living at sea level have a hyporesponsive hypoxia-inducible factor system and blunted physiological responses to hypoxia.
    Petousi N, Croft QP, Cavalleri GL, Cheng HY, Formenti F, Ishida K, Lunn D, McCormack M, Shianna KV, Talbot NP, Ratcliffe PJ, Robbins PA.
    J Appl Physiol (1985); 2014 Apr 01; 116(7):893-904. PubMed ID: 24030663
    [Abstract] [Full Text] [Related]

  • 16. Convergent evolution on the hypoxia-inducible factor (HIF) pathway genes EGLN1 and EPAS1 in high-altitude ducks.
    Graham AM, McCracken KG.
    Heredity (Edinb); 2019 Jun 01; 122(6):819-832. PubMed ID: 30631144
    [Abstract] [Full Text] [Related]

  • 17. Evolutionary selected Tibetan variants of HIF pathway and risk of lung cancer.
    Lanikova L, Reading NS, Hu H, Tashi T, Burjanivova T, Shestakova A, Siwakoti B, Thakur BK, Pun CB, Sapkota A, Abdelaziz S, Feng BJ, Huff CD, Hashibe M, Prchal JT.
    Oncotarget; 2017 Feb 14; 8(7):11739-11747. PubMed ID: 28036300
    [Abstract] [Full Text] [Related]

  • 18. Acute O2 sensing through HIF2α-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors.
    Moreno-Domínguez A, Ortega-Sáenz P, Gao L, Colinas O, García-Flores P, Bonilla-Henao V, Aragonés J, Hüttemann M, Grossman LI, Weissmann N, Sommer N, López-Barneo J.
    Sci Signal; 2020 Jan 21; 13(615):. PubMed ID: 31848220
    [Abstract] [Full Text] [Related]

  • 19. Evolved changes in phenotype across skeletal muscles in deer mice native to high altitude.
    Garrett EJ, Prasad SK, Schweizer RM, McClelland GB, Scott GR.
    Am J Physiol Regul Integr Comp Physiol; 2024 Apr 01; 326(4):R297-R310. PubMed ID: 38372126
    [Abstract] [Full Text] [Related]

  • 20. Mutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasis.
    Yuan G, Peng YJ, Reddy VD, Makarenko VV, Nanduri J, Khan SA, Garcia JA, Kumar GK, Semenza GL, Prabhakar NR.
    Proc Natl Acad Sci U S A; 2013 May 07; 110(19):E1788-96. PubMed ID: 23610397
    [Abstract] [Full Text] [Related]

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