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Journal Abstract Search


133 related items for PubMed ID: 3585909

  • 1. Synthesis and characterization of all four isomers of the muscarinic agonist 2'-methylspiro[1-azabicyclo[2.2.2]octane-3,4'-[1,3]dioxolane].
    Saunders J, Showell GA, Baker R, Freedman SB, Hill D, McKnight A, Newberry N, Salamone JD, Hirshfield J, Springer JP.
    J Med Chem; 1987 Jun; 30(6):969-75. PubMed ID: 3585909
    [Abstract] [Full Text] [Related]

  • 2. Analogues of the muscarinic agent 2'-methylspiro[1-azabicyclo[2.2.2]octane-3,4'-[1,3]dioxolane]: synthesis and pharmacology.
    Nordvall G, Sundquist S, Glas G, Gogoll A, Nilvebrant L, Hacksell U.
    J Med Chem; 1992 May 01; 35(9):1541-50. PubMed ID: 1578479
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and in vitro biological profile of all four isomers of the potent muscarinic agonist 3-(3-methyl-1,2,4-oxadiazol-5-yl)-1-azabicyclo[2.2.1]heptane.
    Showell GA, Baker R, Davis J, Hargreaves R, Freedman SB, Hoogsteen K, Patel S, Snow RJ.
    J Med Chem; 1992 Mar 06; 35(5):911-6. PubMed ID: 1548680
    [Abstract] [Full Text] [Related]

  • 4. 2-Methyl-1,3-dioxaazaspiro[4.5]decanes as novel muscarinic cholinergic agonists.
    Saunders J, Showell GA, Snow RJ, Baker R, Harley EA, Freedman SB.
    J Med Chem; 1988 Feb 06; 31(2):486-91. PubMed ID: 3339620
    [Abstract] [Full Text] [Related]

  • 5. Cholinergic activity of 2-azabicyclo(2.2.2)octane analogs of acetylcholine.
    Borne RF, Clark CR, Waters IW.
    J Pharm Sci; 1974 Oct 06; 63(10):1559-62. PubMed ID: 4436789
    [No Abstract] [Full Text] [Related]

  • 6. Synthesis and muscarinic properties of (1S*,3R*,5R*)-trimethyl(1-methyl-6-oxabicyclo[3.1.0]hex-3-yl)methyl ammonium iodide.
    Giannella M, Piergentili A, Pigini M, Quaglia W, Rafaiani G, Tayebati SK.
    Chem Pharm Bull (Tokyo); 1994 Jun 06; 42(6):1286-90. PubMed ID: 8069977
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and SAR of bulky 1-azabicyclo[2.2.1]-3-one oximes as muscarinic receptor subtype selective agonists.
    Tecle H, Lauffer DJ, Mirzadegan T, Moos WH, Moreland DW, Pavia MR, Schwarz RD, Davis RE.
    Life Sci; 1993 Jun 06; 52(5-6):505-11. PubMed ID: 8382765
    [Abstract] [Full Text] [Related]

  • 8. Muscarinic subtypes profile modulation within a series of new antagonists, bridged bicyclic derivatives of 2,2-diphenyl-[1,3]-dioxolan-4-ylmethyl-dimethylamine.
    Piergentili A, Gentili F, Ghelfi F, Marucci G, Pigini M, Quaglia W, Giannella M.
    Bioorg Med Chem; 2003 Sep 01; 11(18):3901-11. PubMed ID: 12927850
    [Abstract] [Full Text] [Related]

  • 9.
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  • 10. L-689,660, a novel cholinomimetic with functional selectivity for M1 and M3 muscarinic receptors.
    Hargreaves RJ, McKnight AT, Scholey K, Newberry NR, Street LJ, Hutson PH, Semark JE, Harley EA, Patel S, Freedman SB.
    Br J Pharmacol; 1992 Oct 01; 107(2):494-501. PubMed ID: 1422595
    [Abstract] [Full Text] [Related]

  • 11. Drug design and synthesis of a novel kappa opioid receptor agonist with an oxabicyclo[2.2.2]octane skeleton and its pharmacology.
    Nagase H, Watanabe A, Nemoto T, Yamaotsu N, Hayashida K, Nakajima M, Hasebe K, Nakao K, Mochizuki H, Hirono S, Fujii H.
    Bioorg Med Chem Lett; 2010 Jan 01; 20(1):121-4. PubMed ID: 19962305
    [Abstract] [Full Text] [Related]

  • 12.
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  • 13. Stereoisomerism and muscarinic receptor agonists: synthesis and effects of the stereoisomers of 3-[5-(3-amino-1,2,4-oxadiazol)yl]-1- azabicyclo[2.2.1]heptane.
    Pombo-Villar E, Wiederhold KH, Mengod G, Palacios JM, Supavilai P, Boddeke HW.
    Eur J Pharmacol; 1992 Aug 03; 226(4):317-25. PubMed ID: 1397060
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and muscarinic activity of novel aniline derivatives with a 1-azabicyclo[3.3.0]octane moiety.
    Suzuki T, Oka M, Maeda K, Furusawa K, Uesaka H, Kataoka T.
    Chem Pharm Bull (Tokyo); 1999 Jan 03; 47(1):28-36. PubMed ID: 9987823
    [Abstract] [Full Text] [Related]

  • 15. Synthesis, absolute configuration, and molecular modeling study of etoxadrol, a potent phencyclidine-like agonist.
    Thurkauf A, Zenk PC, Balster RL, May EL, George C, Carroll FI, Mascarella SW, Rice KC, Jacobson AE, Mattson MV.
    J Med Chem; 1988 Dec 03; 31(12):2257-63. PubMed ID: 2903930
    [Abstract] [Full Text] [Related]

  • 16. Synthesis of 2-(3-substituted-1,2,4-oxadiazol-5-yl)-8-methyl-8-azabicyclo [3.2.1]octanes and 2 alpha-(3-substituted-1,2,4-oxadiazol-5-yl)-8-methyl-8- azabicyclo[3.2.1]oct-2-enes as potential muscarinic agonists.
    Triggle DJ, Kwon YW, Abraham P, Rahman MA, Carroll FI.
    Pharm Res; 1992 Nov 03; 9(11):1474-9. PubMed ID: 1475236
    [Abstract] [Full Text] [Related]

  • 17. Synthesis of (1-azabicyclo[3.3.0]octanyl)methyl-substituted aromatic heterocycles and their muscarinic activity.
    Suzuki T, Uesaka H, Hamajima H, Ikami T.
    Chem Pharm Bull (Tokyo); 1999 Jun 03; 47(6):876-9. PubMed ID: 10399839
    [Abstract] [Full Text] [Related]

  • 18. Pharmacological characterization of the novel cholinomimetic L-689,660 at cloned and native brain muscarinic receptors.
    Aagaard P, McKinney M.
    J Pharmacol Exp Ther; 1993 Dec 03; 267(3):1478-83. PubMed ID: 8263809
    [Abstract] [Full Text] [Related]

  • 19. Azabicycloalkanes as analgetics. 3. Structure-activity relationships of 1-phenyl-6-azabicyclo[3.2.1]octanes and absolute stereochemistry of (+)-1-(3-hydroxyphenyl)-6-methyl-6-azabicyclo[3.2.1]octane and its 7-endo-methyl derivative.
    Takeda M, Inoue H, Noguchi K, Honma Y, Kawamori M.
    J Med Chem; 1977 Feb 03; 20(2):221-8. PubMed ID: 401892
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and muscarinic activity of the chiral forms of methylenemuscarones.
    De Amici M, De Micheli C, Gianferrara T, Grana E, Dondi G, Ladinsky H, Schiavi G.
    Farmaco; 1993 Oct 03; 48(10):1349-57. PubMed ID: 8117378
    [Abstract] [Full Text] [Related]


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