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Journal Abstract Search

167 related items for PubMed ID: 35877180

  • 1. Hepatic mTORC2 Signaling Facilitates Acute Glucagon Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice.
    Kim T, Nason S, Antipenko J, Finan B, Shalev A, DiMarchi R, Habegger KM.
    Diabetes; 2022 Oct 01; 71(10):2123-2135. PubMed ID: 35877180
    [Abstract] [Full Text] [Related]

  • 2. Hepatic Glucagon Receptor Signaling Enhances Insulin-Stimulated Glucose Disposal in Rodents.
    Kim T, Holleman CL, Nason S, Arble DM, Ottaway N, Chabenne J, Loyd C, Kim JA, Sandoval D, Drucker DJ, DiMarchi R, Perez-Tilve D, Habegger KM.
    Diabetes; 2018 Nov 01; 67(11):2157-2166. PubMed ID: 30150304
    [Abstract] [Full Text] [Related]

  • 3. Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.
    Hagiwara A, Cornu M, Cybulski N, Polak P, Betz C, Trapani F, Terracciano L, Heim MH, Rüegg MA, Hall MN.
    Cell Metab; 2012 May 02; 15(5):725-38. PubMed ID: 22521878
    [Abstract] [Full Text] [Related]

  • 4. Down regulation of Peroxiredoxin-3 in 3T3-L1 adipocytes leads to oxidation of Rictor in the mammalian-target of rapamycin complex 2 (mTORC2).
    Olson DH, Burrill JS, Kuzmicic J, Hahn WS, Park JM, Kim DH, Bernlohr DA.
    Biochem Biophys Res Commun; 2017 Nov 25; 493(3):1311-1317. PubMed ID: 28986255
    [Abstract] [Full Text] [Related]

  • 5. Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance.
    Wang RH, Kim HS, Xiao C, Xu X, Gavrilova O, Deng CX.
    J Clin Invest; 2011 Nov 25; 121(11):4477-90. PubMed ID: 21965330
    [Abstract] [Full Text] [Related]

  • 6. Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism.
    Kumar A, Lawrence JC, Jung DY, Ko HJ, Keller SR, Kim JK, Magnuson MA, Harris TE.
    Diabetes; 2010 Jun 25; 59(6):1397-406. PubMed ID: 20332342
    [Abstract] [Full Text] [Related]

  • 7. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
    Le Bacquer O, Queniat G, Gmyr V, Kerr-Conte J, Lefebvre B, Pattou F.
    J Endocrinol; 2013 Jan 25; 216(1):21-9. PubMed ID: 23092880
    [Abstract] [Full Text] [Related]

  • 8. Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling.
    Zhang C, Wendel AA, Keogh MR, Harris TE, Chen J, Coleman RA.
    Proc Natl Acad Sci U S A; 2012 Jan 31; 109(5):1667-72. PubMed ID: 22307628
    [Abstract] [Full Text] [Related]

  • 9. Sestrin 3 protein enhances hepatic insulin sensitivity by direct activation of the mTORC2-Akt signaling.
    Tao R, Xiong X, Liangpunsakul S, Dong XC.
    Diabetes; 2015 Apr 31; 64(4):1211-23. PubMed ID: 25377878
    [Abstract] [Full Text] [Related]

  • 10. Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
    Tang Y, Wallace M, Sanchez-Gurmaches J, Hsiao WY, Li H, Lee PL, Vernia S, Metallo CM, Guertin DA.
    Nat Commun; 2016 Apr 21; 7():11365. PubMed ID: 27098609
    [Abstract] [Full Text] [Related]

  • 11. Glucagon receptor knockout mice are protected against acute olanzapine-induced hyperglycemia.
    Castellani LN, Peppler WT, Sutton CD, Whitfield J, Charron MJ, Wright DC.
    Psychoneuroendocrinology; 2017 Aug 21; 82():38-45. PubMed ID: 28500893
    [Abstract] [Full Text] [Related]

  • 12. Insulin resistance in striated muscle-specific integrin receptor beta1-deficient mice.
    Zong H, Bastie CC, Xu J, Fassler R, Campbell KP, Kurland IJ, Pessin JE.
    J Biol Chem; 2009 Feb 13; 284(7):4679-88. PubMed ID: 19064993
    [Abstract] [Full Text] [Related]

  • 13. Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.
    Lamming DW, Ye L, Katajisto P, Goncalves MD, Saitoh M, Stevens DM, Davis JG, Salmon AB, Richardson A, Ahima RS, Guertin DA, Sabatini DM, Baur JA.
    Science; 2012 Mar 30; 335(6076):1638-43. PubMed ID: 22461615
    [Abstract] [Full Text] [Related]

  • 14. Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice.
    Tripathy S, Jump DB.
    J Lipid Res; 2013 Jan 30; 54(1):71-84. PubMed ID: 23099444
    [Abstract] [Full Text] [Related]

  • 15. Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor.
    Zhang C, Cooper DE, Grevengoed TJ, Li LO, Klett EL, Eaton JM, Harris TE, Coleman RA.
    Am J Physiol Endocrinol Metab; 2014 Aug 01; 307(3):E305-15. PubMed ID: 24939733
    [Abstract] [Full Text] [Related]

  • 16. Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition.
    Singh BK, Sinha RA, Zhou J, Tripathi M, Ohba K, Wang ME, Astapova I, Ghosh S, Hollenberg AN, Gauthier K, Yen PM.
    J Biol Chem; 2016 Jan 01; 291(1):198-214. PubMed ID: 26453307
    [Abstract] [Full Text] [Related]

  • 17. Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size.
    Gu Y, Lindner J, Kumar A, Yuan W, Magnuson MA.
    Diabetes; 2011 Mar 01; 60(3):827-37. PubMed ID: 21266327
    [Abstract] [Full Text] [Related]

  • 18. Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass.
    Gelling RW, Vuguin PM, Du XQ, Cui L, Rømer J, Pederson RA, Leiser M, Sørensen H, Holst JJ, Fledelius C, Johansen PB, Fleischer N, McIntosh CH, Nishimura E, Charron MJ.
    Am J Physiol Endocrinol Metab; 2009 Sep 01; 297(3):E695-707. PubMed ID: 19602585
    [Abstract] [Full Text] [Related]

  • 19. Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity.
    Kumar A, Harris TE, Keller SR, Choi KM, Magnuson MA, Lawrence JC.
    Mol Cell Biol; 2008 Jan 01; 28(1):61-70. PubMed ID: 17967879
    [Abstract] [Full Text] [Related]

  • 20. Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase.
    Copps KD, Hançer NJ, Qiu W, White MF.
    J Biol Chem; 2016 Apr 15; 291(16):8602-17. PubMed ID: 26846849
    [Abstract] [Full Text] [Related]

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