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173 related items for PubMed ID: 35955600
1. Development of Sesamol Carbamate-L-Phenylalanine Prodrug Targeting L-Type Amino Acid Transporter1 (LAT1) as a Potential Antiproliferative Agent against Melanoma. Srisongkram T, Bahrami K, Järvinen J, Timonen J, Rautio J, Weerapreeyakul N. Int J Mol Sci; 2022 Jul 30; 23(15):. PubMed ID: 35955600 [Abstract] [Full Text] [Related]
2. Role of L-Type Amino Acid Transporter 1 (LAT1) for the Selective Cytotoxicity of Sesamol in Human Melanoma Cells. Srisongkram T, Weerapreeyakul N, Kärkkäinen J, Rautio J. Molecules; 2019 Oct 27; 24(21):. PubMed ID: 31717859 [Abstract] [Full Text] [Related]
3. L-type amino acid transporter 1 utilizing prodrugs of ferulic acid revealed structural features supporting the design of prodrugs for brain delivery. Puris E, Gynther M, Huttunen J, Auriola S, Huttunen KM. Eur J Pharm Sci; 2019 Mar 01; 129():99-109. PubMed ID: 30625368 [Abstract] [Full Text] [Related]
4. Design, synthesis and brain uptake of LAT1-targeted amino acid prodrugs of dopamine. Peura L, Malmioja K, Huttunen K, Leppänen J, Hämäläinen M, Forsberg MM, Gynther M, Rautio J, Laine K. Pharm Res; 2013 Oct 01; 30(10):2523-37. PubMed ID: 24137801 [Abstract] [Full Text] [Related]
7. Route of intracellular uptake and cytotoxicity of sesamol, sesamin, and sesamolin in human melanoma SK-MEL-2 cells. Srisongkram T, Weerapreeyakul N. Biomed Pharmacother; 2022 Feb 01; 146():112528. PubMed ID: 34906777 [Abstract] [Full Text] [Related]
10. Structural Features Affecting the Interactions and Transportability of LAT1-Targeted Phenylalanine Drug Conjugates. Bahrami K, Järvinen J, Laitinen T, Reinisalo M, Honkakoski P, Poso A, Huttunen KM, Rautio J. Mol Pharm; 2023 Jan 02; 20(1):206-218. PubMed ID: 36394563 [Abstract] [Full Text] [Related]
11. Mechanistic Study on the Use of the l-Type Amino Acid Transporter 1 for Brain Intracellular Delivery of Ketoprofen via Prodrug: A Novel Approach Supporting the Development of Prodrugs for Intracellular Targets. Puris E, Gynther M, de Lange ECM, Auriola S, Hammarlund-Udenaes M, Huttunen KM, Loryan I. Mol Pharm; 2019 Jul 01; 16(7):3261-3274. PubMed ID: 31180686 [Abstract] [Full Text] [Related]
15. Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition. Uchino H, Kanai Y, Kim DK, Wempe MF, Chairoungdua A, Morimoto E, Anders MW, Endou H. Mol Pharmacol; 2002 Apr 10; 61(4):729-37. PubMed ID: 11901210 [Abstract] [Full Text] [Related]
16. L-Type Amino Acid Transporter 1 Enables the Efficient Brain Delivery of Small-Sized Prodrug across the Blood-Brain Barrier and into Human and Mouse Brain Parenchymal Cells. Montaser AB, Järvinen J, Löffler S, Huttunen J, Auriola S, Lehtonen M, Jalkanen A, Huttunen KM. ACS Chem Neurosci; 2020 Dec 16; 11(24):4301-4315. PubMed ID: 33228353 [Abstract] [Full Text] [Related]
18. Structure-activity characteristics of phenylalanine analogs selectively transported by L-type amino acid transporter 1 (LAT1). Chen S, Jin C, Ohgaki R, Xu M, Okanishi H, Kanai Y. Sci Rep; 2024 Feb 26; 14(1):4651. PubMed ID: 38409393 [Abstract] [Full Text] [Related]
19. Large neutral amino acid transporter enables brain drug delivery via prodrugs. Gynther M, Laine K, Ropponen J, Leppänen J, Mannila A, Nevalainen T, Savolainen J, Järvinen T, Rautio J. J Med Chem; 2008 Feb 28; 51(4):932-6. PubMed ID: 18217702 [Abstract] [Full Text] [Related]