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133 related items for PubMed ID: 35968594

  • 1. [Blocking PAK1 kinase activity promotes the differentiation of acute megakaryocytic leukemia cells and induces their apoptosis].
    Wang SJ, Wang CQ, Hu XT, Yu XR, Fu CL.
    Zhonghua Xue Ye Xue Za Zhi; 2022 Jun 14; 43(6):499-505. PubMed ID: 35968594
    [Abstract] [Full Text] [Related]

  • 2. A unique role of GATA1s in Down syndrome acute megakaryocytic leukemia biology and therapy.
    Xavier AC, Edwards H, Dombkowski AA, Balci TB, Berman JN, Dellaire G, Xie C, Buck SA, Matherly LH, Ge Y, Taub JW.
    PLoS One; 2011 Jun 14; 6(11):e27486. PubMed ID: 22110660
    [Abstract] [Full Text] [Related]

  • 3. Targeting cyclin-dependent kinases 4/6 inhibits survival of megakaryoblasts in acute megakaryoblastic leukaemia.
    Qi K, Hu X, Yu X, Cheng H, Wang C, Wang S, Wang Y, Li Y, Cao J, Pan B, Wu Q, Qiao J, Zeng L, Li Z, Xu K, Fu C.
    Leuk Res; 2022 Sep 14; 120():106920. PubMed ID: 35872339
    [Abstract] [Full Text] [Related]

  • 4. PAK1 overexpression promotes cell proliferation in cutaneous T cell lymphoma via suppression of PUMA and p21.
    Wang Y, Gu X, Li W, Zhang Q, Zhang C.
    J Dermatol Sci; 2018 Apr 14; 90(1):60-67. PubMed ID: 29307600
    [Abstract] [Full Text] [Related]

  • 5. Arsenic trioxide mediates intrinsic and extrinsic pathways of apoptosis and cell cycle arrest in acute megakaryocytic leukemia.
    Lam HK, Li K, Chik KW, Yang M, Liu VC, Li CK, Fok TF, Ng PC, Shing MM, Chuen CK, Yuen PM.
    Int J Oncol; 2005 Aug 14; 27(2):537-45. PubMed ID: 16010437
    [Abstract] [Full Text] [Related]

  • 6. Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.
    Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Goldberg L, Birger Y, Izraeli S, Gamis AS, Smith FO, Woods WG, Taub J, Scherer CA, Bradner JE, Goh BC, Mercher T, Carpenter AE, Gould RJ, Clemons PA, Carr SA, Root DE, Schreiber SL, Stern AM, Crispino JD.
    Cell; 2012 Aug 03; 150(3):575-89. PubMed ID: 22863010
    [Abstract] [Full Text] [Related]

  • 7. Fasudil promotes polyploidization of megakaryoblasts in an acute megakaryocyte leukemia model.
    He B, Wang C, Niu J, Wang F, Zhang Y, Gao Y, Yang Q.
    Naunyn Schmiedebergs Arch Pharmacol; 2023 Nov 03; 396(11):3101-3110. PubMed ID: 37162543
    [Abstract] [Full Text] [Related]

  • 8. SON inhibits megakaryocytic differentiation via repressing RUNX1 and the megakaryocytic gene expression program in acute megakaryoblastic leukemia.
    Vukadin L, Kim JH, Park EY, Stone JK, Ungerleider N, Baddoo MC, Kong HK, Richard A, Tran J, Giannini H, Flemington EK, Lim SS, Ahn EE.
    Cancer Gene Ther; 2021 Sep 03; 28(9):1000-1015. PubMed ID: 33247227
    [Abstract] [Full Text] [Related]

  • 9. PAK1 Inhibition Suppresses the Proliferation, Migration and Invasion of Glioma Cells.
    Yi Q, Chen T, Zhou K, Ma Q, Sun Z, Shi H.
    Curr Protein Pept Sci; 2023 Sep 03; 24(2):178-189. PubMed ID: 36573046
    [Abstract] [Full Text] [Related]

  • 10. β-elemene enhances the radiosensitivity of gastric cancer cells by inhibiting Pak1 activation.
    Liu JS, Che XM, Chang S, Qiu GL, He SC, Fan L, Zhao W, Zhang ZL, Wang SF.
    World J Gastroenterol; 2015 Sep 14; 21(34):9945-56. PubMed ID: 26379399
    [Abstract] [Full Text] [Related]

  • 11. BMP2K dysregulation promotes abnormal megakaryopoiesis in acute megakaryoblastic leukemia.
    Wang M, Zhang T, Zhang X, Jiang Z, Peng M, Huang Z.
    Cell Biosci; 2020 Sep 14; 10():57. PubMed ID: 32322386
    [Abstract] [Full Text] [Related]

  • 12. Nuclear factor of activated T cells c1 mediates p21-activated kinase 1 activation in the modulation of chemokine-induced human aortic smooth muscle cell F-actin stress fiber formation, migration, and proliferation and injury-induced vascular wall remodeling.
    Kundumani-Sridharan V, Singh NK, Kumar S, Gadepalli R, Rao GN.
    J Biol Chem; 2013 Jul 26; 288(30):22150-62. PubMed ID: 23737530
    [Abstract] [Full Text] [Related]

  • 13. JAK2T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model.
    Mercher T, Wernig G, Moore SA, Levine RL, Gu TL, Fröhling S, Cullen D, Polakiewicz RD, Bernard OA, Boggon TJ, Lee BH, Gilliland DG.
    Blood; 2006 Oct 15; 108(8):2770-9. PubMed ID: 16804112
    [Abstract] [Full Text] [Related]

  • 14. Molecular pathways: induction of polyploidy as a novel differentiation therapy for leukemia.
    Krause DS, Crispino JD.
    Clin Cancer Res; 2013 Nov 15; 19(22):6084-8. PubMed ID: 23963861
    [Abstract] [Full Text] [Related]

  • 15. [The role of mitogen-activated protein kinase cascades in inhibition of proliferation in human prostate carcinoma cells by raloxifene: an in vitro experiment].
    Zhang YX, Kong CZ.
    Zhonghua Yi Xue Za Zhi; 2008 Jan 22; 88(4):271-5. PubMed ID: 18361842
    [Abstract] [Full Text] [Related]

  • 16. PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation.
    Qing H, Gong W, Che Y, Wang X, Peng L, Liang Y, Wang W, Deng Q, Zhang H, Jiang B.
    Tumour Biol; 2012 Aug 22; 33(4):985-94. PubMed ID: 22252525
    [Abstract] [Full Text] [Related]

  • 17. Effect of PAK1 gene silencing on proliferation and apoptosis in hepatocellular carcinoma cell lines MHCC97-H and HepG2 and cells in xenograft tumor.
    Zhang ZL, Liu GC, Peng L, Zhang C, Jia YM, Yang WH, Mao L.
    Gene Ther; 2018 Jul 22; 25(4):284-296. PubMed ID: 29802374
    [Abstract] [Full Text] [Related]

  • 18. Baicalein antagonizes acute megakaryoblastic leukemia in vitro and in vivo by inducing cell cycle arrest.
    Yu C, Zeng J, Yan Z, Ma Z, Liu S, Huang Z.
    Cell Biosci; 2016 Jul 22; 6():20. PubMed ID: 27042290
    [Abstract] [Full Text] [Related]

  • 19. Effects of metformin on proliferation and apoptosis of human megakaryoblastic Dami and MEG-01 cells.
    Liang X, Kong P, Wang J, Xu Y, Gao C, Guo G.
    J Pharmacol Sci; 2017 Sep 22; 135(1):14-21. PubMed ID: 28927780
    [Abstract] [Full Text] [Related]

  • 20. Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21(WAF1/Cip1) by STAT5.
    Matsumura I, Ishikawa J, Nakajima K, Oritani K, Tomiyama Y, Miyagawa J, Kato T, Miyazaki H, Matsuzawa Y, Kanakura Y.
    Mol Cell Biol; 1997 May 22; 17(5):2933-43. PubMed ID: 9111365
    [Abstract] [Full Text] [Related]

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