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Journal Abstract Search

131 related items for PubMed ID: 36075969

  • 1. High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development.
    Kottur J, Rechkoblit O, Quintana-Feliciano R, Sciaky D, Aggarwal AK.
    Nat Struct Mol Biol; 2022 Sep; 29(9):850-853. PubMed ID: 36075969
    [Abstract] [Full Text] [Related]

  • 2. High resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development.
    Aggarwal A, Kottur J.
    Res Sq; 2022 Mar 08. PubMed ID: 35291302
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  • 3. Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals.
    Kottur J, White KM, Rodriguez ML, Rechkoblit O, Quintana-Feliciano R, Nayar A, García-Sastre A, Aggarwal AK.
    PLoS Pathog; 2023 Jul 08; 19(7):e1011546. PubMed ID: 37523415
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  • 4. Potent Inhibition of SARS-CoV-2 nsp14 N7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues.
    Ahmed-Belkacem R, Hausdorff M, Delpal A, Sutto-Ortiz P, Colmant AMG, Touret F, Ogando NS, Snijder EJ, Canard B, Coutard B, Vasseur JJ, Decroly E, Debart F.
    J Med Chem; 2022 Apr 28; 65(8):6231-6249. PubMed ID: 35439007
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  • 5. High-resolution structures of the SARS-CoV-2 2'-O-methyltransferase reveal strategies for structure-based inhibitor design.
    Rosas-Lemus M, Minasov G, Shuvalova L, Inniss NL, Kiryukhina O, Brunzelle J, Satchell KJF.
    Sci Signal; 2020 Sep 29; 13(651):. PubMed ID: 32994211
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  • 9. Structure-guided optimization of adenosine mimetics as selective and potent inhibitors of coronavirus nsp14 N7-methyltransferases.
    Hausdorff M, Delpal A, Barelier S, Nicollet L, Canard B, Touret F, Colmant A, Coutard B, Vasseur JJ, Decroly E, Debart F.
    Eur J Med Chem; 2023 Aug 05; 256():115474. PubMed ID: 37192550
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  • 10. Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19.
    Selvaraj C, Dinesh DC, Panwar U, Abhirami R, Boura E, Singh SK.
    J Biomol Struct Dyn; 2021 Aug 05; 39(13):4582-4593. PubMed ID: 32567979
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  • 12. Synthetic Platforms for Characterizing and Targeting of SARS-CoV-2 Genome Capping Enzymes.
    Ornelas MY, Thomas AY, Johnson Rosas LI, Scoville RO, Mehta AP.
    ACS Synth Biol; 2022 Nov 18; 11(11):3759-3771. PubMed ID: 36331143
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  • 14. Activation of the SARS-CoV-2 NSP14 3'-5' exoribonuclease by NSP10 and response to antiviral inhibitors.
    Riccio AA, Sullivan ED, Copeland WC.
    J Biol Chem; 2022 Jan 18; 298(1):101518. PubMed ID: 34942146
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  • 15. In silico evaluation of S-adenosyl-L-homocysteine analogs as inhibitors of nsp14-viral cap N7 methyltranferase and PLpro of SARS-CoV-2: synthesis, molecular docking, physicochemical data, ADMET and molecular dynamics simulations studies.
    Srivastava R, Panda SK, Sen Gupta PS, Chaudhary A, Naaz F, Yadav AK, Ram NK, Rana MK, Singh RK, Srivastava R.
    J Biomol Struct Dyn; 2023 Dec 26; ():1-18. PubMed ID: 38147408
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  • 16. New targets for drug design: importance of nsp14/nsp10 complex formation for the 3'-5' exoribonucleolytic activity on SARS-CoV-2.
    Saramago M, Bárria C, Costa VG, Souza CS, Viegas SC, Domingues S, Lousa D, Soares CM, Arraiano CM, Matos RG.
    FEBS J; 2021 Sep 26; 288(17):5130-5147. PubMed ID: 33705595
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  • 17. Crystal structures and fragment screening of SARS-CoV-2 NSP14 reveal details of exoribonuclease activation and mRNA capping and provide starting points for antiviral drug development.
    Imprachim N, Yosaatmadja Y, Newman JA.
    Nucleic Acids Res; 2023 Jan 11; 51(1):475-487. PubMed ID: 36546776
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  • 18. Identification and evaluation of potential SARS-CoV-2 antiviral agents targeting mRNA cap guanine N7-Methyltransferase.
    Kasprzyk R, Spiewla TJ, Smietanski M, Golojuch S, Vangeel L, De Jonghe S, Jochmans D, Neyts J, Kowalska J, Jemielity J.
    Antiviral Res; 2021 Sep 11; 193():105142. PubMed ID: 34303749
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  • 19. Computational Analysis of SAM Analogs as Methyltransferase Inhibitors of nsp16/nsp10 Complex from SARS-CoV-2.
    Balieiro AM, Anunciação ELS, Costa CHS, Qayed WS, Silva JRA.
    Int J Mol Sci; 2022 Nov 12; 23(22):. PubMed ID: 36430451
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  • 20. The conformational changes of Zika virus methyltransferase upon converting SAM to SAH.
    Zhou H, Wang F, Wang H, Chen C, Zhang T, Han X, Wang D, Chen C, Wu C, Xie W, Wang Z, Zhang L, Wang L, Yang H.
    Oncotarget; 2017 Feb 28; 8(9):14830-14834. PubMed ID: 28122329
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