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Journal Abstract Search

350 related items for PubMed ID: 36116789

  • 21. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.
    Moore LB, Parks DJ, Jones SA, Bledsoe RK, Consler TG, Stimmel JB, Goodwin B, Liddle C, Blanchard SG, Willson TM, Collins JL, Kliewer SA.
    J Biol Chem; 2000 May 19; 275(20):15122-7. PubMed ID: 10748001
    [Abstract] [Full Text] [Related]

  • 22. Targeting xenobiotic receptors PXR and CAR for metabolic diseases.
    Gao J, Xie W.
    Trends Pharmacol Sci; 2012 Oct 19; 33(10):552-8. PubMed ID: 22889594
    [Abstract] [Full Text] [Related]

  • 23. CAR and PXR: xenosensors of endocrine disrupters?
    Kretschmer XC, Baldwin WS.
    Chem Biol Interact; 2005 Aug 15; 155(3):111-28. PubMed ID: 16054614
    [Abstract] [Full Text] [Related]

  • 24. Small-molecule modulators of PXR and CAR.
    Chai SC, Cherian MT, Wang YM, Chen T.
    Biochim Biophys Acta; 2016 Sep 15; 1859(9):1141-1154. PubMed ID: 26921498
    [Abstract] [Full Text] [Related]

  • 25. Targeting Xenobiotic Nuclear Receptors PXR and CAR to Prevent Cobicistat Hepatotoxicity.
    Shehu AI, Zhu J, Li J, Lu J, McMahon D, Xie W, Gonzalez FJ, Ma X.
    Toxicol Sci; 2021 Apr 27; 181(1):58-67. PubMed ID: 33629115
    [Abstract] [Full Text] [Related]

  • 26. Master regulation of bile acid and xenobiotic metabolism via the FXR, PXR and CAR trio.
    Modica S, Bellafante E, Moschetta A.
    Front Biosci (Landmark Ed); 2009 Jan 01; 14(12):4719-45. PubMed ID: 19273385
    [Abstract] [Full Text] [Related]

  • 27. Xenobiotic Nuclear Receptors Pregnane X Receptor and Constitutive Androstane Receptor Regulate Antiretroviral Drug Efflux Transporters at the Blood-Testis Barrier.
    Whyte-Allman SK, Hoque MT, Jenabian MA, Routy JP, Bendayan R.
    J Pharmacol Exp Ther; 2017 Dec 01; 363(3):324-335. PubMed ID: 28970358
    [Abstract] [Full Text] [Related]

  • 28. Xenobiotic-sensing nuclear receptors CAR and PXR as drug targets in cholestatic liver disease.
    Kakizaki S, Takizawa D, Tojima H, Yamazaki Y, Mori M.
    Curr Drug Targets; 2009 Nov 01; 10(11):1156-1163. PubMed ID: 19925451
    [Abstract] [Full Text] [Related]

  • 29. A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response.
    Scheer N, Ross J, Rode A, Zevnik B, Niehaves S, Faust N, Wolf CR.
    J Clin Invest; 2008 Sep 01; 118(9):3228-39. PubMed ID: 18677425
    [Abstract] [Full Text] [Related]

  • 30. Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.
    Kandel BA, Thomas M, Winter S, Damm G, Seehofer D, Burk O, Schwab M, Zanger UM.
    Biochim Biophys Acta; 2016 Sep 01; 1859(9):1218-1227. PubMed ID: 26994748
    [Abstract] [Full Text] [Related]

  • 31. Differences in Gene Regulation by Dual Ligands of Nuclear Receptors Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) in HepG2 Cells Stably Expressing CAR/PXR.
    Kanno Y, Tanuma N, Yazawa S, Zhao S, Inaba M, Nakamura S, Nemoto K, Inouye Y.
    Drug Metab Dispos; 2016 Aug 01; 44(8):1158-63. PubMed ID: 27197997
    [Abstract] [Full Text] [Related]

  • 32. New insights on the xenobiotic-sensing nuclear receptors in liver diseases--CAR and PXR--.
    Kakizaki S, Yamazaki Y, Takizawa D, Negishi M.
    Curr Drug Metab; 2008 Sep 01; 9(7):614-21. PubMed ID: 18781913
    [Abstract] [Full Text] [Related]

  • 33. Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters.
    Chen Y, Tang Y, Guo C, Wang J, Boral D, Nie D.
    Biochem Pharmacol; 2012 Apr 15; 83(8):1112-26. PubMed ID: 22326308
    [Abstract] [Full Text] [Related]

  • 34. Characterization of ligand-dependent activation of bovine and pig constitutive androstane (CAR) and pregnane X receptors (PXR) with interspecies comparisons.
    Küblbeck J, Zancanella V, Prantner V, Molnár F, Squires EJ, Dacasto M, Honkakoski P, Giantin M.
    Xenobiotica; 2016 Apr 15; 46(3):200-10. PubMed ID: 26153444
    [Abstract] [Full Text] [Related]

  • 35. Pregnane X receptor and constitutive androstane receptor at the crossroads of drug metabolism and energy metabolism.
    Gao J, Xie W.
    Drug Metab Dispos; 2010 Dec 15; 38(12):2091-5. PubMed ID: 20736325
    [Abstract] [Full Text] [Related]

  • 36. Molecular basis of crosstalk in nuclear receptors: heterodimerization between PXR and CAR and the implication in gene regulation.
    Bwayi MN, Garcia-Maldonado E, Chai SC, Xie B, Chodankar S, Huber AD, Wu J, Annu K, Wright WC, Lee HM, Seetharaman J, Wang J, Buchman CD, Peng J, Chen T.
    Nucleic Acids Res; 2022 Apr 08; 50(6):3254-3275. PubMed ID: 35212371
    [Abstract] [Full Text] [Related]

  • 37. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
    Shizu R, Benoki S, Numakura Y, Kodama S, Miyata M, Yamazoe Y, Yoshinari K.
    PLoS One; 2013 Apr 08; 8(4):e61802. PubMed ID: 23626729
    [Abstract] [Full Text] [Related]

  • 38. Rational quantitative structure-activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands.
    Dring AM, Anderson LE, Qamar S, Stoner MA.
    Chem Biol Interact; 2010 Dec 05; 188(3):512-25. PubMed ID: 20869355
    [Abstract] [Full Text] [Related]

  • 39. The nuclear receptors constitutive androstane receptor and pregnane X receptor cross-talk with hepatic nuclear factor 4alpha to synergistically activate the human CYP2C9 promoter.
    Chen Y, Kissling G, Negishi M, Goldstein JA.
    J Pharmacol Exp Ther; 2005 Sep 05; 314(3):1125-33. PubMed ID: 15919766
    [Abstract] [Full Text] [Related]

  • 40. Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.
    Wei P, Zhang J, Dowhan DH, Han Y, Moore DD.
    Pharmacogenomics J; 2002 Sep 05; 2(2):117-26. PubMed ID: 12049174
    [Abstract] [Full Text] [Related]

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