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Journal Abstract Search

541 related items for PubMed ID: 36191430

  • 1. Novel 1,3-diaryl pyrazole derivatives bearing methylsulfonyl moiety: Design, synthesis, molecular docking and dynamics, with dual activities as anti-inflammatory and anticancer agents through selectively targeting COX-2.
    Shaker AMM, Shahin MI, AboulMagd AM, Abdel Aleem SA, Abdel-Rahman HM, Abou El Ella DA.
    Bioorg Chem; 2022 Dec; 129():106143. PubMed ID: 36191430
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis, modeling studies and biological evaluation of pyrazole derivatives linked to oxime and nitrate moieties as nitric oxide donor selective COX-2 and aromatase inhibitors with dual anti-inflammatory and anti-neoplastic activities.
    A A Fadaly W, A M M Elshaier Y, T M Nemr M, R A Abdellatif K.
    Bioorg Chem; 2023 May; 134():106428. PubMed ID: 36893546
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  • 3. Novel tetrazole-based selective COX-2 inhibitors: Design, synthesis, anti-inflammatory activity, evaluation of PGE2, TNF-α, IL-6 and histopathological study.
    Labib MB, Fayez AM, El-Nahass ES, Awadallah M, Halim PA.
    Bioorg Chem; 2020 Nov; 104():104308. PubMed ID: 33011534
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation of pyridazinone derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents.
    Ahmed EM, Kassab AE, El-Malah AA, Hassan MSA.
    Eur J Med Chem; 2019 Jun 01; 171():25-37. PubMed ID: 30904755
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  • 5. Discovery of new 2-(3-(naphthalen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazole derivatives with potential analgesic and anti-inflammatory activities: In vitro, in vivo and in silico investigations.
    Mohammed ER, Abd-El-Fatah AH, Mohamed AR, Mahrouse MA, Mohammad MA.
    Bioorg Chem; 2024 Jun 01; 147():107372. PubMed ID: 38653152
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  • 6. New 1,2,4-triazole/pyrazole hybrids linked to oxime moiety as nitric oxide donor celecoxib analogs: Synthesis, cyclooxygenase inhibition anti-inflammatory, ulcerogenicity, anti-proliferative activities, apoptosis, molecular modeling and nitric oxide release studies.
    Fadaly WAA, Elshaier YAMM, Hassanein EHM, Abdellatif KRA.
    Bioorg Chem; 2020 May 01; 98():103752. PubMed ID: 32197148
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis, and molecular docking of novel pyrazole-chalcone analogs of lonazolac as 5-LOX, iNOS and tubulin polymerization inhibitors with potential anticancer and anti-inflammatory activities.
    Ahmed AHH, Mohamed MFA, Allam RM, Nafady A, Mohamed SK, Gouda AE, Beshr EAM.
    Bioorg Chem; 2022 Dec 01; 129():106171. PubMed ID: 36166898
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  • 9. New pyridazine derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents; design, synthesis and biological evaluation.
    Ahmed EM, Hassan MSA, El-Malah AA, Kassab AE.
    Bioorg Chem; 2020 Jan 01; 95():103497. PubMed ID: 31838289
    [Abstract] [Full Text] [Related]

  • 10. Selective cyclooxygenase inhibition and ulcerogenic liability of some newly prepared anti-inflammatory agents having thiazolo[4,5-d]pyrimidine scaffold.
    Bakr RB, Ghoneim AA, Azouz AA.
    Bioorg Chem; 2019 Jul 01; 88():102964. PubMed ID: 31075742
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  • 12. Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on celecoxib scaffold supported with in vivo anti-inflammatory activity, ulcerogenic liability, ADME profiling and docking study.
    Abdellatif KRA, Abdelall EKA, Elshemy HAH, Philoppes JN, Hassanein EHM, Kahk NM.
    Bioorg Chem; 2022 Mar 01; 120():105627. PubMed ID: 35065465
    [Abstract] [Full Text] [Related]

  • 13. Tailored quinoline hybrids as promising COX-2/15-LOX dual inhibitors endowed with diverse safety profile: Design, synthesis, SAR, and histopathological study.
    Hegazy ME, Taher ES, Ghiaty AH, Bayoumi AH.
    Bioorg Chem; 2024 Apr 01; 145():107244. PubMed ID: 38428284
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  • 14. New Ferrocene Compounds as Selective Cyclooxygenase (COX-2) Inhibitors: Design, Synthesis, Cytotoxicity and Enzyme-inhibitory Activity.
    Farzaneh S, Zeinalzadeh E, Daraei B, Shahhosseini S, Zarghi A.
    Anticancer Agents Med Chem; 2018 Apr 01; 18(2):295-301. PubMed ID: 28971779
    [Abstract] [Full Text] [Related]

  • 15. Synthesis of Hydroxybenzofuranyl-pyrazolyl and Hydroxyphenyl-pyrazolyl Chalcones and Their Corresponding Pyrazoline Derivatives as COX Inhibitors, Anti-inflammatory and Gastroprotective Agents.
    Ragab FAE, Mohammed EI, Abdel Jaleel GA, Selim AAMAE, Nissan YM.
    Chem Pharm Bull (Tokyo); 2020 Apr 01; 68(8):742-752. PubMed ID: 32741915
    [Abstract] [Full Text] [Related]

  • 16. Trimethoxyphenyl containing compounds: Synthesis, biological evaluation, nitric oxide release, modeling, histochemical and histopathological studies.
    Abdelall EKA, Lamie PF, Aboelnaga LS, Hassan RM.
    Bioorg Chem; 2022 Jul 01; 124():105806. PubMed ID: 35436752
    [Abstract] [Full Text] [Related]

  • 17. Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes.
    Maghraby MT, Abou-Ghadir OMF, Abdel-Moty SG, Ali AY, Salem OIA.
    Bioorg Med Chem; 2020 Apr 01; 28(7):115403. PubMed ID: 32127262
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  • 19. Design, Synthesis, Molecular docking, and biological evaluation of novel 2,3-diaryl-1,3-thiazolidine-4-one derivatives as potential anti-inflammatory and cytotoxic agents.
    Mekhlef YO, AboulMagd AM, Gouda AM.
    Bioorg Chem; 2023 Apr 01; 133():106411. PubMed ID: 36801792
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