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235 related items for PubMed ID: 36209275
21. Oral administration of Robinia pseudoacacia L. flower exosome-like nanoparticles attenuates gastric and small intestinal mucosal ferroptosis caused by hypoxia through inhibiting HIF-1α- and HIF-2α-mediated lipid peroxidation. Wang D, Zhang H, Liao X, Li J, Zeng J, Wang Y, Zhang M, Ma X, Wang X, Ren F, Wang Y, Li M, Xu J, Jin P, Sheng J. J Nanobiotechnology; 2024 Aug 12; 22(1):479. PubMed ID: 39134988 [Abstract] [Full Text] [Related]
22. Selective HIF stabilization alleviates hepatocellular steatosis and ballooning in a rodent model of 70% liver resection. Iesari S, Leclercq I, Joudiou N, Komuta M, Daumerie A, Ambroise J, Dili A, Feza-Bingi N, Xhema D, Bouzin C, Gallez B, Pisani F, Bonaccorsi-Riani E, Gianello P. Clin Sci (Lond); 2021 Oct 15; 135(19):2285-2305. PubMed ID: 34550341 [Abstract] [Full Text] [Related]
23. The prolyl hydroxylase inhibitor roxadustat: Paradigm in drug discovery and prospects for clinical application beyond anemia. Su K, Li Z, Yu Y, Zhang X. Drug Discov Today; 2020 Jul 15; 25(7):1262-1269. PubMed ID: 32380083 [Abstract] [Full Text] [Related]
24. Atypical induction of HIF-1α expression by pericellular Notch1 signaling suffices for the malignancy of glioblastoma multiforme cells. Lee J, Kim E, Chong K, Ryu SW, Kim C, Choi K, Kim JH, Choi C. Cell Mol Life Sci; 2022 Oct 02; 79(10):537. PubMed ID: 36183290 [Abstract] [Full Text] [Related]
25. Roxadustat promotes angiogenesis through HIF-1α/VEGF/VEGFR2 signaling and accelerates cutaneous wound healing in diabetic rats. Zhu Y, Wang Y, Jia Y, Xu J, Chai Y. Wound Repair Regen; 2019 Jul 02; 27(4):324-334. PubMed ID: 30817065 [Abstract] [Full Text] [Related]
26. Reduction of obliterative bronchiolitis (OB) by prolyl-hydroxylase-inhibitors activating hypoxia-inducible transcription factors in an experimental mouse model. Heim C, Motsch B, Jalilova S, Bernhardt WM, Ramsperger-Gleixner M, Burzlaff N, Weyand M, Eckardt KU, Ensminger SM. Transpl Immunol; 2016 Nov 02; 39():66-73. PubMed ID: 27590486 [Abstract] [Full Text] [Related]
27. Hypoxia-inducible miR-196a modulates glioblastoma cell proliferation and migration through complex regulation of NRAS. Takkar S, Sharma V, Ghosh S, Suri A, Sarkar C, Kulshreshtha R. Cell Oncol (Dordr); 2021 Apr 02; 44(2):433-451. PubMed ID: 33469841 [Abstract] [Full Text] [Related]
28. The HIFα-Stabilizing Drug Roxadustat Increases the Number of Renal Epo-Producing Sca-1+ Cells. Jatho A, Zieseniss A, Brechtel-Curth K, Guo J, Böker KO, Salinas G, Wenger RH, Katschinski DM. Cells; 2022 Feb 21; 11(4):. PubMed ID: 35203399 [Abstract] [Full Text] [Related]
29. Roxadustat Attenuates Adverse Remodeling Following Myocardial Infarction in Mice. Zaruba MM, Staggl S, Ghadge SK, Maurer T, Gavranovic-Novakovic J, Jeyakumar V, Schönherr P, Wimmer A, Pölzl G, Bauer A, Messner M. Cells; 2024 Jun 21; 13(13):. PubMed ID: 38994928 [Abstract] [Full Text] [Related]
30. Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells. Wing PAC, Keeley TP, Zhuang X, Lee JY, Prange-Barczynska M, Tsukuda S, Morgan SB, Harding AC, Argles ILA, Kurlekar S, Noerenberg M, Thompson CP, Huang KA, Balfe P, Watashi K, Castello A, Hinks TSC, James W, Ratcliffe PJ, Davis I, Hodson EJ, Bishop T, McKeating JA. Cell Rep; 2021 Apr 20; 35(3):109020. PubMed ID: 33852916 [Abstract] [Full Text] [Related]
31. Sestrin2 inhibits hypoxia-inducible factor-1α accumulation via AMPK-mediated prolyl hydroxylase regulation. Seo K, Seo S, Ki SH, Shin SM. Free Radic Biol Med; 2016 Dec 20; 101():511-523. PubMed ID: 27840318 [Abstract] [Full Text] [Related]
32. Activation of transcription factor HIF inhibits IL-1β-induced NO production in primary cultured rat hepatocytes. Yoshida T, Okumura T, Matsuo Y, Okuyama T, Michiura T, Kaibori M, Umezaki N, Bono H, Hirota K, Sekimoto M. Nitric Oxide; 2022 Jul 01; 124():1-14. PubMed ID: 35460897 [Abstract] [Full Text] [Related]
33. JTZ-951 (enarodustat), a hypoxia-inducibe factor prolyl hydroxylase inhibitor, stabilizes HIF-α protein and induces erythropoiesis without effects on the function of vascular endothelial growth factor. Fukui K, Shinozaki Y, Kobayashi H, Deai K, Yoshiuchi H, Matsui T, Matsuo A, Matsushita M, Tanaka T, Nangaku M. Eur J Pharmacol; 2019 Sep 15; 859():172532. PubMed ID: 31301309 [Abstract] [Full Text] [Related]
34. Whether Prolyl Hydroxylase Blocker-Roxadustat-In the Treatment of Anemia in Patients with Chronic Kidney Disease Is the Future? Grzeszczak W, Szczyra D, Śnit M. Int J Environ Res Public Health; 2021 Feb 08; 18(4):. PubMed ID: 33567688 [Abstract] [Full Text] [Related]
35. Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system. Siddiq A, Ayoub IA, Chavez JC, Aminova L, Shah S, LaManna JC, Patton SM, Connor JR, Cherny RA, Volitakis I, Bush AI, Langsetmo I, Seeley T, Gunzler V, Ratan RR. J Biol Chem; 2005 Dec 16; 280(50):41732-43. PubMed ID: 16227210 [Abstract] [Full Text] [Related]
36. Pharmacologic stabilization of hypoxia-inducible transcription factors protects developing mouse brain from hypoxia-induced apoptotic cell death. Trollmann R, Richter M, Jung S, Walkinshaw G, Brackmann F. Neuroscience; 2014 Oct 10; 278():327-42. PubMed ID: 25162122 [Abstract] [Full Text] [Related]
37. Increased activation of the hypoxia-inducible factor pathway in varicose veins. Lim CS, Kiriakidis S, Paleolog EM, Davies AH. J Vasc Surg; 2012 May 10; 55(5):1427-39. PubMed ID: 22277691 [Abstract] [Full Text] [Related]
38. Hypoxia-mediated mitochondria apoptosis inhibition induces temozolomide treatment resistance through miR-26a/Bad/Bax axis. Ge X, Pan MH, Wang L, Li W, Jiang C, He J, Abouzid K, Liu LZ, Shi Z, Jiang BH. Cell Death Dis; 2018 Nov 13; 9(11):1128. PubMed ID: 30425242 [Abstract] [Full Text] [Related]
39. Esterification promotes the intracellular accumulation of roxadustat, an activator of hypoxia-inducible factors, to extend its effective duration. Nakai T, Saigusa D, Iwamura Y, Matsumoto Y, Umeda K, Kato K, Yamaki H, Tomioka Y, Hirano I, Koshiba S, Yamamoto M, Suzuki N. Biochem Pharmacol; 2022 Mar 13; 197():114939. PubMed ID: 35114188 [Abstract] [Full Text] [Related]
40. HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron. Singhal R, Mitta SR, Das NK, Kerk SA, Sajjakulnukit P, Solanki S, Andren A, Kumar R, Olive KP, Banerjee R, Lyssiotis CA, Shah YM. J Clin Invest; 2021 Jun 15; 131(12):. PubMed ID: 33914705 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]