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Journal Abstract Search

268 related items for PubMed ID: 36331143

  • 1. Synthetic Platforms for Characterizing and Targeting of SARS-CoV-2 Genome Capping Enzymes.
    Ornelas MY, Thomas AY, Johnson Rosas LI, Scoville RO, Mehta AP.
    ACS Synth Biol; 2022 Nov 18; 11(11):3759-3771. PubMed ID: 36331143
    [Abstract] [Full Text] [Related]

  • 2. Mutagenesis of S-Adenosyl-l-Methionine-Binding Residues in Coronavirus nsp14 N7-Methyltransferase Demonstrates Differing Requirements for Genome Translation and Resistance to Innate Immunity.
    Case JB, Ashbrook AW, Dermody TS, Denison MR.
    J Virol; 2016 Aug 15; 90(16):7248-7256. PubMed ID: 27252528
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  • 4. Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication.
    Ogando NS, El Kazzi P, Zevenhoven-Dobbe JC, Bontes BW, Decombe A, Posthuma CC, Thiel V, Canard B, Ferron F, Decroly E, Snijder EJ.
    Proc Natl Acad Sci U S A; 2021 Dec 07; 118(49):. PubMed ID: 34845015
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  • 5. The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2.
    Ogando NS, Zevenhoven-Dobbe JC, van der Meer Y, Bredenbeek PJ, Posthuma CC, Snijder EJ.
    J Virol; 2020 Nov 09; 94(23):. PubMed ID: 32938769
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  • 6. Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19.
    Selvaraj C, Dinesh DC, Panwar U, Abhirami R, Boura E, Singh SK.
    J Biomol Struct Dyn; 2021 Aug 09; 39(13):4582-4593. PubMed ID: 32567979
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  • 7. Characterization, Directed Evolution, and Targeting of DNA Virus-Encoded RNA Capping Enzymes Using Phenotypic Yeast Platforms.
    Ornelas MY, Thomas AY, Johnson Rosas LI, Medina GN, Mehta AP.
    ACS Chem Biol; 2023 Aug 18; 18(8):1808-1820. PubMed ID: 37498174
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  • 8. Structure-guided optimization of adenosine mimetics as selective and potent inhibitors of coronavirus nsp14 N7-methyltransferases.
    Hausdorff M, Delpal A, Barelier S, Nicollet L, Canard B, Touret F, Colmant A, Coutard B, Vasseur JJ, Decroly E, Debart F.
    Eur J Med Chem; 2023 Aug 05; 256():115474. PubMed ID: 37192550
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  • 10. Potent Inhibition of SARS-CoV-2 nsp14 N7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues.
    Ahmed-Belkacem R, Hausdorff M, Delpal A, Sutto-Ortiz P, Colmant AMG, Touret F, Ogando NS, Snijder EJ, Canard B, Coutard B, Vasseur JJ, Decroly E, Debart F.
    J Med Chem; 2022 Apr 28; 65(8):6231-6249. PubMed ID: 35439007
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  • 11. Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase.
    Chen Y, Cai H, Pan J, Xiang N, Tien P, Ahola T, Guo D.
    Proc Natl Acad Sci U S A; 2009 Mar 03; 106(9):3484-9. PubMed ID: 19208801
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  • 12. A universal fluorescence polarization high throughput screening assay to target the SAM-binding sites of SARS-CoV-2 and other viral methyltransferases.
    Samrat SK, Bashir Q, Zhang R, Huang Y, Liu Y, Wu X, Brown T, Wang W, Zheng YG, Zhang QY, Chen Y, Li Z, Li H.
    Emerg Microbes Infect; 2023 Dec 03; 12(1):2204164. PubMed ID: 37060263
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  • 13. Structure-function analysis of severe acute respiratory syndrome coronavirus RNA cap guanine-N7-methyltransferase.
    Chen Y, Tao J, Sun Y, Wu A, Su C, Gao G, Cai H, Qiu S, Wu Y, Ahola T, Guo D.
    J Virol; 2013 Jun 03; 87(11):6296-305. PubMed ID: 23536667
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  • 14. Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals.
    Kottur J, White KM, Rodriguez ML, Rechkoblit O, Quintana-Feliciano R, Nayar A, García-Sastre A, Aggarwal AK.
    PLoS Pathog; 2023 Jul 03; 19(7):e1011546. PubMed ID: 37523415
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  • 15. Crystal structures and fragment screening of SARS-CoV-2 NSP14 reveal details of exoribonuclease activation and mRNA capping and provide starting points for antiviral drug development.
    Imprachim N, Yosaatmadja Y, Newman JA.
    Nucleic Acids Res; 2023 Jan 11; 51(1):475-487. PubMed ID: 36546776
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  • 16. Porcine Epidemic Diarrhea Virus Deficient in RNA Cap Guanine-N-7 Methylation Is Attenuated and Induces Higher Type I and III Interferon Responses.
    Lu Y, Cai H, Lu M, Ma Y, Li A, Gao Y, Zhou J, Gu H, Li J, Gu J.
    J Virol; 2020 Jul 30; 94(16):. PubMed ID: 32461321
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  • 17. Localization of SARS-CoV-2 Capping Enzymes Revealed by an Antibody against the nsp10 Subunit.
    Horova V, Landova B, Hodek J, Chalupsky K, Krafcikova P, Chalupska D, Duchoslav V, Weber J, Boura E, Klima M.
    Viruses; 2021 Jul 29; 13(8):. PubMed ID: 34452352
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  • 18. Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading.
    Yan L, Yang Y, Li M, Zhang Y, Zheng L, Ge J, Huang YC, Liu Z, Wang T, Gao S, Zhang R, Huang YY, Guddat LW, Gao Y, Rao Z, Lou Z.
    Cell; 2021 Jun 24; 184(13):3474-3485.e11. PubMed ID: 34143953
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  • 19. New targets for drug design: importance of nsp14/nsp10 complex formation for the 3'-5' exoribonucleolytic activity on SARS-CoV-2.
    Saramago M, Bárria C, Costa VG, Souza CS, Viegas SC, Domingues S, Lousa D, Soares CM, Arraiano CM, Matos RG.
    FEBS J; 2021 Sep 24; 288(17):5130-5147. PubMed ID: 33705595
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  • 20. Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry.
    Pearson LA, Green CJ, Lin D, Petit AP, Gray DW, Cowling VH, Fordyce EAF.
    SLAS Discov; 2021 Jul 24; 26(6):749-756. PubMed ID: 33724070
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