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208 related items for PubMed ID: 36374307

  • 1. Tanshinone IIA promotes apoptosis by downregulating BCL2 and upregulating TP53 in triple-negative breast cancer.
    Liu J, Zhang C, Liu S, Wang X, Wu X, Hao J.
    Naunyn Schmiedebergs Arch Pharmacol; 2023 Feb; 396(2):365-374. PubMed ID: 36374307
    [Abstract] [Full Text] [Related]

  • 2. Tanshinone IIA enhances the inhibitory effect of imatinib on proliferation and motility of acute leukemia cell line TIB‑152 in vivo and in vitro by inhibiting the PI3K/AKT/mTOR signaling pathway.
    Teng Z, Xu S, Lei Q.
    Oncol Rep; 2020 Feb; 43(2):503-515. PubMed ID: 31894340
    [Abstract] [Full Text] [Related]

  • 3. Tanshinone IIA induces apoptosis in human lung cancer A549 cells through the induction of reactive oxygen species and decreasing the mitochondrial membrane potential.
    Chiu TL, Su CC.
    Int J Mol Med; 2010 Feb; 25(2):231-6. PubMed ID: 20043132
    [Abstract] [Full Text] [Related]

  • 4. Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway.
    Won SH, Lee HJ, Jeong SJ, Lee HJ, Lee EO, Jung DB, Shin JM, Kwon TR, Yun SM, Lee MH, Choi SH, Lü J, Kim SH.
    Biol Pharm Bull; 2010 Feb; 33(11):1828-34. PubMed ID: 21048307
    [Abstract] [Full Text] [Related]

  • 5. Tanshinone IIA Inhibits Triple-Negative Breast Cancer Cells MDA-MB-231 via G Protein-Coupled Estrogen Receptor- (GPER-) Dependent Signaling Pathway.
    He Y, Yang K, Liu J, Shi D, Zhang Z, Yang J, Chen M, Zhao P.
    Dis Markers; 2023 Feb; 2023():8371623. PubMed ID: 36741908
    [Abstract] [Full Text] [Related]

  • 6. Tanshinone I attenuates the malignant biological properties of ovarian cancer by inducing apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway.
    Zhou J, Jiang YY, Chen H, Wu YC, Zhang L.
    Cell Prolif; 2020 Feb; 53(2):e12739. PubMed ID: 31820522
    [Abstract] [Full Text] [Related]

  • 7. Tanshinone IIA inhibits viral oncogene expression leading to apoptosis and inhibition of cervical cancer.
    Munagala R, Aqil F, Jeyabalan J, Gupta RC.
    Cancer Lett; 2015 Jan 28; 356(2 Pt B):536-46. PubMed ID: 25304375
    [Abstract] [Full Text] [Related]

  • 8. Tanshinone IIA affects the malignant growth of Cholangiocarcinoma cells by inhibiting the PI3K-Akt-mTOR pathway.
    Liu H, Liu C, Wang M, Sun D, Zhu P, Zhang P, Tan X, Shi G.
    Sci Rep; 2021 Sep 29; 11(1):19268. PubMed ID: 34588580
    [Abstract] [Full Text] [Related]

  • 9. Tanshinone IIA Affects Autophagy and Apoptosis of Glioma Cells by Inhibiting Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Signaling Pathway.
    Ding L, Ding L, Wang S, Wang S, Wang W, Wang W, Lv P, Lv P, Zhao D, Zhao D, Chen F, Chen F, Meng T, Meng T, Dong L, Dong L, Qi L, Qi L.
    Pharmacology; 2017 Sep 29; 99(3-4):188-195. PubMed ID: 27889779
    [Abstract] [Full Text] [Related]

  • 10. Experimental study of the anti-cancer mechanism of tanshinone IIA against human breast cancer.
    Lu Q, Zhang P, Zhang X, Chen J.
    Int J Mol Med; 2009 Dec 29; 24(6):773-80. PubMed ID: 19885617
    [Abstract] [Full Text] [Related]

  • 11. Tanshinone IIA inhibits proliferation and migration by downregulation of the PI3K/Akt pathway in small cell lung cancer cells.
    Jiang Y, Bi Y, Zhou L, Zheng S, Jian T, Chen J.
    BMC Complement Med Ther; 2024 Jan 31; 24(1):68. PubMed ID: 38297301
    [Abstract] [Full Text] [Related]

  • 12. Tanshinone IIA protects against myocardial ischemia reperfusion injury by activating the PI3K/Akt/mTOR signaling pathway.
    Li Q, Shen L, Wang Z, Jiang HP, Liu LX.
    Biomed Pharmacother; 2016 Dec 31; 84():106-114. PubMed ID: 27643552
    [Abstract] [Full Text] [Related]

  • 13. Resveratrol mediated the proliferation and apoptosis of gastric cancer cells by modulating the PI3K/Akt/P53 signaling pathway.
    Dong Q, Zheng A, Zhai H, Zhang T.
    Biochem Biophys Res Commun; 2024 Sep 03; 723():150186. PubMed ID: 38830298
    [Abstract] [Full Text] [Related]

  • 14. Tanshinone IIA inhibited intermittent hypoxia induced neuronal injury through promoting autophagy via AMPK-mTOR signaling pathway.
    Si J, Liu B, Qi K, Chen X, Li D, Yang S, Ji E.
    J Ethnopharmacol; 2023 Oct 28; 315():116677. PubMed ID: 37268259
    [Abstract] [Full Text] [Related]

  • 15. Tanshinone IIA induces ER stress and JNK activation to inhibit tumor growth and enhance anti-PD-1 immunotherapy in non-small cell lung cancer.
    Zhang YZ, Lai HL, Huang C, Jiang ZB, Yan HX, Wang XR, Xie C, Huang JM, Ren WK, Li JX, Zhai ZR, Yao XJ, Wu QB, Leung EL.
    Phytomedicine; 2024 Jun 28; 128():155431. PubMed ID: 38537440
    [Abstract] [Full Text] [Related]

  • 16. Tanshinone IIA decreases the protein expression of EGFR, and IGFR blocking the PI3K/Akt/mTOR pathway in gastric carcinoma AGS cells both in vitro and in vivo.
    Su CC, Chiu TL.
    Oncol Rep; 2016 Aug 28; 36(2):1173-9. PubMed ID: 27277844
    [Abstract] [Full Text] [Related]

  • 17. The antitumor natural product tanshinone IIA inhibits protein kinase C and acts synergistically with 17-AAG.
    Lv C, Zeng HW, Wang JX, Yuan X, Zhang C, Fang T, Yang PM, Wu T, Zhou YD, Nagle DG, Zhang WD.
    Cell Death Dis; 2018 Feb 07; 9(2):165. PubMed ID: 29416003
    [Abstract] [Full Text] [Related]

  • 18. Tanshinone IIA inhibits gastric carcinoma AGS cells through increasing p-p38, p-JNK and p53 but reducing p-ERK, CDC2 and cyclin B1 expression.
    Su CC.
    Anticancer Res; 2014 Dec 07; 34(12):7097-110. PubMed ID: 25503137
    [Abstract] [Full Text] [Related]

  • 19. Tanshinone IIA triggers p53 responses and apoptosis by RNA polymerase II upon DNA minor groove binding.
    Zhang Z, Gao J, Wang Y, Song T, Zhang J, Wu G, Zhang T, Du G.
    Biochem Pharmacol; 2009 Nov 15; 78(10):1316-22. PubMed ID: 19591811
    [Abstract] [Full Text] [Related]

  • 20. Regulation of the cell cycle and PI3K/Akt/mTOR signaling pathway by tanshinone I in human breast cancer cell lines.
    Wang L, Wu J, Lu J, Ma R, Sun D, Tang J.
    Mol Med Rep; 2015 Feb 15; 11(2):931-9. PubMed ID: 25355053
    [Abstract] [Full Text] [Related]

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